Phlebodia - instructions for use. Phlebodia is an effective angioprotective drug based on diosmin. Interaction with other drugs.

Phlebodia 600, international name"Diosmin" - angioprotective drug.

Produced in France in the INNOTHERA CHOUZY laboratory.

The pharmacological group of the drug is angioprotectors.

Release form and composition of the drug

The drug is available in round, convex tablets with a pink film coating. The tablets are packaged in blisters of 15 pieces and placed in cardboard packages along with instructions for use.

A pack may contain 1 or 2 blisters, that is, 15 or 30 tablets.

Active ingredient Phlebodia 600 is "Diosmin" - 600 mg, for auxiliary products relate:

• microcrystalline cellulose - 910 mg;
• stearic acid – 50.05 mg;
• colloidal silicon dioxide – 3.5 mg;
• talc – 10.24 mg.

Compound shells:

• shellac - 150 mcg;
• beeswax - 75 mcg;
• carnauba wax - 75 mcg;
• red oxide - 20 mcg;
• black oxide - 130 mcg;
• crimson dye - 401 mcg;
• titanium dioxide – 4.026 mg;
• hypromellose, propylene glycol - 458 mcg;
• macrogol stearate – 1.967 mg;
• microcrystalline cellulose – 7.866 mg;
• hypromellose – 9.832 mg.

The drug has a number of active substance analogues, which differ in the content of excipients.

pharmachologic effect

Thanks to diosmin (the active ingredient), the medicine has the following properties:

• venotonic effect;
• reduces stagnation in the veins and also increases their tone;
• improves capillary resistance, increasing lymphatic drainage and microcirculation;
• has an anti-inflammatory effect;
• is a regulator of blood supply to the skin;
• blocks free radicals, the synthesis of thromboxane and prostaglandins.

The drug also enhances the vasoconstrictor effects of norepinephrine (norepinephrine), adrenaline (epinephrine).

Pharmacokinetics of the drug

Phlebodia 600 is well absorbed into the blood plasma from the gastrointestinal tract, where it is observed after 2 hours from the time of administration.

After 5 hours, cmax in blood plasma is reached.

Distribution process

The drug is evenly distributed and also accumulates in the walls of the cava and saphenous veins located in the lower extremities.

To a lesser extent it is contained in the veins of the lungs, liver, kidneys and other tissues. Selective accumulation in the venous vessels is achieved a maximum of 9 hours after administration and persists for 96 hours, after which 79% is excreted in the urine, 11% in feces and 2.4% in bile.

Indications, contraindications and precautions for use

Instructions for use for Phlebodia 600 indicate that the drug shown when:

• microcirculation disorders;
• hemorrhoids;
• chronic lymphovenous insufficiency lower limbs;
• varicose veins in the lower extremities.

The drug is contraindicated at:

• increased susceptibility to the components of the drug;
• lactation;
• children, as well as teenagers under 18 years of age.

Cautions when taking the drug

Before taking Phlebodia 600 tablets, need to consider:

1. People whose activities are associated with increased concentration of attention (drivers of mechanical vehicles) should not be afraid of treatment with the drug. Vehicle), since it does not have an effect that inhibits a person’s reaction;
2. If necessary, it can be used during pregnancy, but is prohibited when breastfeeding, although there is no data on the penetration of the drug into milk;
3. Can be used with medications of other groups.

Doses and methods of application depending on the disease

Dosages vary depending on the disease.

For hemorrhoids

During an exacerbation of hemorrhoids

• reduces the manifestation of venous stasis in hemorrhoidal veins;
• neutralizes inflammation;
• relieves pain and unpleasant feelings.

The drug should be taken during meals, 2-3 tablets. The course of therapy is 1 week.

Venous insufficiency

Used in combination with other drugs indicated for the treatment of this disease, it is only an addition to them. Purpose of treatment:

• slow down the progression of the disease;
• prevent complications;
• improve quality of life (relieve pain, reduce swelling).

The drug is used 1 time in the morning, before eating breakfast. The course of treatment depends on the severity diseases:

• in mild cases – 2 months;
• for convulsions and trophic disorders - from 3 to 4 months;
• for trophic ulcers – 6 months.

During pregnancy

The drug is prescribed for the treatment of lymphovenous insufficiency in chronic form in the 2nd or 3rd trimester of pregnancy.

Prescribed dose: 1 tablet. /1 rub. per day Admission is stopped 14 days before the expected birth.

No overdose symptoms have been observed to date. And reviews from patients who took Phlebodia 600 during pregnancy are mostly positive.

Side effects

What negative consequences can it cause? taking the drug:

• manifestation of allergic reactions. In this case, treatment must be interrupted;
• headache;
• dyspepsia.

If these manifestations occur, you should consult a doctor to review the prescribed dose.

special instructions

To treat acute hemorrhoids, it is necessary to take Phlebodia 600 in combination with other drugs.

If there are no positive results in the near future, it is necessary to be examined again and adjust the therapy.

There is evidence that the drug is effective in preventing bleeding that can occur due to the use of an intrauterine device, as well as during phlebectomy.

How much does Phlebodia 600 cost?

The price of Phlebodia 600 depends on the number of blisters in the package, as well as on the region of purchase.

They can vary:

• “Phlebodia 600” 15 tablets – 395 00 – 695 00 rub.;
• “Phlebodia 600” 30 tablets – 685 00 – 1,742,00 rub.

You can buy Phlebodia 600 in pharmacies or pharmacy points with a doctor's prescription.

Its validity period is 3 years, After this time, the medicine loses its potency and is prohibited for use.

The storage temperature should not exceed 30 C, and the place where the medicine is kept should be out of reach of children.

Phlebodia 600 is a drug that helps fight varicose veins in the legs. Phlebodia belongs to the group of angioprotective drugs. This means that the action of this drug is aimed at protecting and restoring already weakened veins that have lost their tone.

The venotonic effect of the drug is caused by its component – ​​diosmin. This is an active substance that has a direct effect on the human body as a whole.

The drug Phlebodia 600 has many analogues in its main component, but they all differ in a variety of additional (auxiliary) substances. Manufacturer of this medicine– French laboratory “INNOTHERA CHOUZY”.

Release form and composition

Phlebodia 600 is available in tablet form. The tablets are convex, round, 15 pieces in a blister. Usually a pack contains 1 or 2 blisters, that is, a package contains 15 or 30 tablets.

The composition includes the active substance diosmin. The dosage of diosmin is 600 mg. Among the excipients, microcrystalline cellulose at a dosage of 910 mg, stearic acid - 50.05 mg, colloidal silicon dioxide - 3.5 mg and talc - 10.24 mg can be distinguished.

Indications for use

Instructions for use show this drug:

• for trophic disorders of the lower extremities;
• with venous insufficiency;
• For thrombophlebitis
• with heaviness in the legs;
• with lymphatic insufficiency;
• with superpermeability of capillaries;
• with exacerbation of hemorrhoids.
• When spider veins appear

Contraindications

Phlebodia tablets for varicose veins are contraindicated in patients prone to allergies. It is also undesirable for patients with chronic diseases kidneys and liver.

Side effects

Side effects include allergies, stomach upset, and headache. Often this drug does not cause negative effects, so it can be taken during pregnancy, but only after consulting a doctor.

How to take the medicine?

Treatment of varicose veins is effective if the drug is taken correctly. Very often patients are interested in:

“How often can you take this drug?”, or “How to take it: before or after meals?” The answer is of interest to many, so you can read this information further.

The medicine must be taken one tablet before meals, preferably in the morning. The course of treatment is a month, in some cases – two months. This depends primarily on the extent to which the veins in the legs are affected and the degree of the disease.

Phlebodia for varicose veins of the pelvis helps to increase the tone of the veins, as well as microcirculation of blood in them, has an anti-inflammatory effect, and helps reduce blood stagnation in the veins. However, such a medicine for varicose veins of the legs requires compliance with special rules during treatment. First of all, you should:

• Avoid prolonged exposure to the sun.
• Monitor your weight and try to reduce it as much as possible (if you are obese).
• To walk outside.
• Combine treatments (take pills, ointments and wear special clothing).

It is not easy to follow such rules, especially at first, but this will ensure effective and quick recovery and help avoid the negative consequences of a disease such as varicose veins.

Methods of using the drug for various diseases

Depending on the disease and its degree, dosages vary.

1. Phlebodia with hemorrhoids.

During hemorrhoids, the drug is allowed to be taken 2 or 3 tablets per day. Take during meals. The course of treatment is 7 days.

For hemorrhoids, this drug helps reduce the occurrence of hemorrhoidal veins, helps neutralize inflammation, pain and unpleasant feelings.

1. Phlebodia with varicose veins.

This drug is indicated for use in combination with other venotonic drugs. Compliance with this treatment regimen allows you to:

• slow down further progression of the disease;
• prevent possible complications;
• take off pain and reduce swelling of the legs.

Phlebodia should be taken once a day before breakfast in the morning. The course of treatment is from 2 to 6 months, depending on the degree of the disease.

1. Phlebodia during pregnancy.

During pregnancy, this drug is indicated for the treatment of chronic lymphovenous insufficiency in the last two trimesters of pregnancy (second and third trimesters).

Please note that when taking Phlebodia, you must stop taking it 14 days before the expected date of birth. Overdose of drugs during pregnancy has not been identified. Feedback from patients during this period was positive.

Instructions from the drug packaging

How much does this drug cost?

The price of a drug such as Phlebodia directly depends on the region of purchase and the number of tablets.

For example, when purchasing Phlebodia 600 No. 15, you will need to pay from 395 to 695 rubles.

And when purchasing “Phlebodia 600” No. 30, the cost will be approximately from 685 to 1742 rubles. per package. You can buy this drug at any pharmacy or pharmacy.

Phlebodia and alcohol

The drug is compatible with alcohol. This means that alcohol does not affect the effect of the drug in any way. However, this cannot be abused, since taking this drug is often combined with other venotonics, and they, in turn, are not always compatible with alcohol.

Phlebodia when taking oc (oral contraceptives)

Quite often, many women are interested in the question of whether it is possible to take oral contraceptives in combination with Phlebodia 600 venotonic. The answer is yes, you can. This drug is approved for use in combination with contraceptives, but a doctor's consultation is necessary before taking.

Analogues

Among the analogues of Phlebodia 600 we can highlight the following drugs: Vasoket 600 and Diovenor 600. These are generic drugs, that is, they are absolute analogues of Phlebodia 600.

The drug Diosmin is Russian analogue Phlebodia. It contains 500 mg of active substance.

This drug also differs in the number of excipients, as well as its popularity among consumers.

Detralex

The drug Detralex is similar to Phlebodia, but contains 450 mg of diosmin and 50 mg of hesperedin.

The difference is that Detralex is excreted through the gastrointestinal tract, which makes it possible for people with kidney and liver disease to take it.

The drug Venolek contains 500 mg of diosmin. The difference between it and Phlebodia is that it causes many side effects.

Quite often, patients complain of rashes, pruritus, headaches and frequent dizziness.

Some experience a decrease blood pressure, vomiting and nausea occur. Venolek is a cheap analogue of Phlebodia. Excreted by the kidneys and intestines.

There are also analogues that have the same effect as Phlebodia, but they differ in composition, cost and release form. These include:

• Venarus.
• Troxevasin gel.
• Venoruton.
• Solcoseryl gel.
• Flexital.
• Thromboass.

The basis and active ingredient of Phlebodia 600 is purified anhydrous diosmin. It is contained in an amount of 600 mg in granular form.

There are also auxiliary components:

• stearic acid;
• microcrystalline cellulose (also contained in the shell);
• colloidal silicon dioxide;
• talc.

The composition of phlebodia includes a shell made of the following substances:

• iron oxide red and black;
• titanium dioxide;
• red conishel;
• macrogol stearate;
• carnauba (palm) and beeswax;
• shellac;
• hypromellose;
• polyethylene glycol stearate.

The active substance of the drug acts mainly on the state of the venous bed:

• reduces stretching;
• increases tone;
• helps strengthen capillaries and prevents their damage;
• indirectly reduces congestion in the veins;
• increases lymphatic drainage;
• reduces the permeability of the walls of venous vessels.

The effect of increasing the tone in direct proportion depends on the amount of the drug taken (dose-dependence). Thanks to Phlebodia, there is an improvement in the blood supply to peripheral tissues and skin.

IN latest research it has been proven that the drug can act on biologically active substances, activating the action of adrenaline and norepinephrine when they narrow the lumen of blood vessels. It also reduces the flow of white blood cells into the veins and prevents the formation of free radicals. This is how its anti-inflammatory effect manifests itself.

Phlebodia 600 is available in the form of tablets convex on both sides, with a special protective shell on top. The blister contains 15 pieces. This form was adopted by the manufacturer and continues to this day.

The active substance of this drug is an angioprotector, and is intended to strengthen blood vessels. Diomin belongs to flavonoids, it improves microcirculation, and thus optimizes local metabolic processes.

The drug is taken orally and is rapidly absorbed, after about two hours half the dose is determined in the blood, and the maximum concentration is reached after five hours. Redistribution in the body occurs 9 hours after administration. It occurs in such a way that the main part of diosmin falls on the inferior vena cava and venous vessels of the extremities. Final elimination occurs after 96 hours.

Indications and contraindications

What does this medicine help with? The main indications for the use of Phlebodia 600 are the main abilities of diosmin to improve blood flow in the veins and capillary network:

• chronic venous insufficiency;
• prevention of orthostatic hypotension and collapse after surgery;
• prevention of bleeding after;

According to some experts, the drug can prevent the development of hemorrhagic disorders during the use of an intrauterine device. Phlebodia's compatibility with other drugs is good.

There are also contraindications to the use of the active substance:

• age under 18 years;
• breastfeeding (no studies on penetration into human milk);
• first trimester of pregnancy;
• individual intolerance to the active substance and other components (very rare).

Side effects

When using the drug Phlebodia 600 side effects usually noted only in exceptional cases. Most patients tolerate it satisfactorily, but sometimes:

• digestive disorders (nausea, vomiting, diarrhea);
• headache.

If such signs appear, you should stop taking the drug and consult your doctor about reviewing treatment. Typically, unwanted effects go away immediately after use is stopped, and no special methods are required to remove the substance from the body.

Alcohol combined with diosmin can produce unexpected results. When they are compatible, ulcers appear on the gastric mucosa and the risk of internal bleeding increases. Therefore, drinking alcoholic beverages is not recommended for the entire duration of treatment to prevent unwanted reactions.

How to use

Venous insufficiency

How to take Phlebodia 600 for varicose veins? In case of blood stagnation and the development of venous insufficiency, drinking Phlebodia 600 is usually recommended as an addition to the complex treatment of pathology.

Diosmin helps slow down the rate of progression of pathology, prevents the development of complications, and reduces discomfort (pain, heaviness, discomfort). It also helps reduce the severity of edema syndrome, and therefore improves the patient’s quality of life. The drug is taken once, on an empty stomach in the morning.

The duration of use depends on the severity of the process:

• for uncomplicated variants of the disease, treatment continues for 60 days;
• when a patient occasionally experiences cramps and dry skin, Phlebodia 600 is taken for 3-4 months;
• the appearance is an indication for longer use (up to six months).

After completing the full course, you need to take a break (at least 4 months), after which treatment can be continued if necessary. To prevent varicose veins, it is enough to take one tablet per day for 1-2 months.

Exacerbation of hemorrhoids

Phlebodia 600 for hemorrhoids relieves the manifestations of inflammation and blood stasis in the nodes. This helps relieve tension and discomfort. In this case, you should take 2-3 tablets during the day, along with your usual food. The general course of treatment during the acute process is one week. The convenience of using tablets in this disease is that their use is possible in a public place and does not require privacy (unlike ointment or rectal suppositories).

When you drink this remedy for acute hemorrhoids, you should not use topical angioprotective ointments, as they are only intended for application to the skin. For the treatment of bumps and cracks in anus you should buy special suppositories and creams.

Use of the drug in pregnant women

Is it possible to use this product for pregnant women? The doctor may prescribe the use of the drug during pregnancy in the presence of chronic lymphatic and venous insufficiency. The drug is not recommended to be taken in the first trimester, when the formation of organs and systems of the fetus occurs; in later stages, no negative effects on the fetus were found.

Phlebodia 600 is used for a long time during pregnancy, 1 tablet per day. Therapy is discontinued two weeks before the expected due date to avoid causing bleeding. In this case, as a rule, there is no deterioration of the condition or side effects. The drug has positive action on the blood circulation of the placenta, indirectly improving the development of the unborn baby.

Phlebodia or Troxevasin?

If there are problems with venous outflow, specialists in some cases may prescribe another venotonic – Troxevasin. What is the difference between it and Phlebodia, and what is better to take?

The indications for use of these drugs are the same and they are classified according to their classification into one group - venotonics. But active substance they have different things. Taking into account the individual characteristics of each human body, you need to understand that the reaction to a particular drug may be different. If the patient has previously taken one drug, then if undesirable effects occur, it can be easily replaced with a different type of venotonic.

Troxevasin contains 300 mg of troxerutin, which is a glycoside. Diosmin is derived from hesperidin, a substance found in citrus fruits. Contraindications to the use of Troxevasin are almost the same, but it should not be taken if you are prone to gastrointestinal bleeding.

The final decision on the use of Troxevasin or Phlebodia remains with the doctor. In severe cases, they can be used simultaneously (it is especially effective to combine tablets and gel for external use).

The drug manufacturer claims that Troxevasin can be taken from the age of 15, and Phlebodia 600 tablets are recommended exclusively after 18. Both drugs are not prescribed in the first three months of pregnancy and during lactation.

Analogues

Full generics of Phlebodia 600 are Vasoket 600 and Diovenor 600. They have a similar composition in terms of the active substance. However, their manufacturer is different, and they are not as widespread. There are also Diosmin tablets, but the content of the active component in them is slightly less - 500 mg.

A very popular analogue of the drug Phlebodia 600 is the drug Detralex. It includes 50 grams of hesperidin and 450 grams of diosmin. Due to this, the product has high efficiency with venous stagnation. The medicine is prepared using a unique micronization method, and therefore the active substance is absorbed very quickly and without loss in the intestines. Since it is excreted primarily through the gastrointestinal tract, it is chosen for the treatment of those patients who have problems with the functioning of the kidneys and heart muscle. The drug has exactly the same composition and effect.

If stagnation of blood and lymph develops in the lower extremities and pelvis, you should go to a specialist and begin treatment. To relieve symptoms and improve your condition, you should stop smoking, normalize your weight, lead an active lifestyle and take medications.

The basic rule for taking the venotonic drug Phlebodia 600 is strict adherence to the dosage and doctor’s instructions for its use. Most often, the medicine is prescribed together with other drugs, and combines well with them without causing negative reactions. Separately from others, it can be used as a prophylaxis for varicose veins and hemorrhoids.

Useful video about Phlebodia 600

Phlebodia 600 is a French vein protector. It has a phlebotonic effect, which increases the tone of the veins and eliminates venous congestion. The drug Phlebodia 600 is recognized as the most popular drug used in phlebology. Available in several forms, requiring the correct approach to use.

The main area of ​​application of the product is the prevention and treatment of varicose veins. Phlebodia also effectively fights hemorrhoids and prostatitis. All the nuances of using the drug are discussed in detail in the article.

To understand why Phlebodia is in high demand among consumers, you first need to become more familiar with the composition of the drug and the principle of its action.

The drug belongs to the group of venoprotector drugs. Has INN (International Nonproprietary Name) Diosmin. Used in the prevention and treatment of venous pathologies.

Compound

The composition of the medicine in tablet form includes the following components:

The gel, in addition to the main active ingredient, contains menthol.

Pharmacodynamics and pharmacokinetics

Phlebodia has a phlebotonic effect and allows:

When taken orally, the active substances of the drug are quickly absorbed from the gastrointestinal tract ( gastrointestinal tract). In blood plasma they are determined after a couple of hours, the maximum concentration of the substance in the bloodstream is after 5 hours.

The drug has the ability to be evenly distributed in the layers of the vena cava and saphenous veins, as well as accumulate in them. The therapeutic effect lasts for a long time, up to 96 hours. Medicinal components are excreted from the body primarily by the kidneys.

Release forms and prices, average for Moscow and St. Petersburg

The drug is available in the form of tablets and gel. It is known that Phlebodia 600 is used in the treatment of hemorrhoids. However, contrary to popular belief, the medicine is not available in the form of suppositories (suppositories)!

The average cost of the drug depending on the form of release and dosage in Moscow and St. Petersburg is presented in Table. 1.

Table 1 - Cost

Despite the fact that the drug is dispensed from pharmacies without a doctor's prescription, it is not recommended to use it for self-medication.

Indications, contraindications.

Prescribed for the following pathologies:

The medicine is well tolerated and has a minimum of contraindications. It is prohibited for use if the body is individually intolerant to the components of the drug.

Prescribed with caution during pregnancy and breastfeeding. Due to insufficient clinical data regarding the effect of Phlebodia on children and adolescents, the drug is not recommended for patients under 18 years of age.

Possible side effects

The drug rarely causes negative effects, but in some cases it is possible. Drinking alcohol during therapy has a particularly negative impact on health.

General Negative Reactions

The use of Phlebodia can lead to a number of side effects:

• nausea;
• pain in the abdomen;
• heartburn;
• headache;
• development of allergic reactions.

If negative consequences occur when using the drug or if side effects not described in the instructions occur, you must stop using it and seek medical advice.

Phlebodia 600 is prescribed with extreme caution if there is a tendency to develop allergic reactions. Also at risk are patients with disorders of the liver and kidneys, especially if they are chronic.

Compatibility with alcohol and consequences

As for Phlebodia 600 tablets, you should not combine them with alcohol. There is a high risk of developing side effects such as:

• severe headache;
• diarrhea;
• digestive disorders.

Experts note that when drinking alcohol, the therapeutic effect of the drug is significantly reduced, up to its complete absence.

Since Phlebodia 600 directly affects vascular system, a malfunction of the veins and blood vessels may occur.

If Phlebodia is used in complex therapy(in combination with a number of other drugs), drinking alcohol is strictly unacceptable. This can lead not only to a decrease in therapeutic effect, but also to serious health consequences. The most dangerous of them:

• severe liver damage;
• stomach bleeding;
• formation of trophic ulcers.

It is also possible that:

• general malaise, weakness;
• severe headache, noise, ringing in the ears.

Instructions for using tablets and gel for varicose veins

Treatment of varicose veins requires an integrated approach, for which external and systemic agents must be taken. Simultaneous therapy with tablets and Phlebodia ointment is often prescribed.

Indications, dosage, risks

Phlebodia 600 in the form of an ointment (gel) is prescribed primarily for pathologies of the lower extremities (discomfort, a feeling of heaviness in the legs, varicose veins, the appearance of spider veins).

The product is applied in a thin layer to the affected area on the surface of the skin. Rub into the skin with soft, massaging movements, moving from the ankles to the thighs. It is necessary to wait until the drug is completely absorbed. After the procedure, you should refrain from water procedures for the next few hours.

The procedure is repeated twice a day, morning and evening. The recommended duration of therapy is 2-3 months. If necessary, treatment can be extended at the discretion of the doctor.

When using Phlebodia 600, it is necessary to avoid contact with the eyes and mucous membranes. It is unacceptable to apply ointment or gel to the affected areas of the skin, open wounds. If the product is applied inappropriately, there is a high risk of itching, burning, and redness on the skin.

To enhance the therapeutic effect in the treatment of varicose veins, it is possible to prescribe complex treatment - the combined use of gel and Phlebodia 600 tablets. According to experts, the tablets significantly enhance the effectiveness of therapy by affecting the veins and blood vessels from the inside. Phlebodia is recognized as one of the most powerful venoprotectors; in tablet form it can be prescribed as monotherapy.

For varicose veins, a tablet is prescribed once a day. It is recommended to take the drug in the first half of the day, half an hour before meals. Duration of therapy is from 3 to 4 months.

Reviews from doctors and patients

Phlebologists and their patients tell us how effective the drug Phlebodia 600 is in the treatment of varicose veins:

Salekh A.Z., doctor: “A high-quality French venotonic, in terms of action in the treatment of varicose veins, has proven to be more powerful compared to many similar drugs. For severe, advanced forms of varicose veins in my patients, I prefer tablets; they have a more targeted effect on the affected veins.”

Kazarin S.V., doctor:“Phlebodia 600 is one of the best original venoprotectors. The powerful composition allows you to restore veins affected by varicose veins, without negatively affecting the patient’s body. Side effects are rare; in most cases they are limited to an allergy to the drug.”

Elena, 36 years old, Kaliningrad:“The varicose veins on my legs progressed very quickly, my attending physician began to insist on surgery. I turned to another specialist who prescribed me Phlebodia 600 in combination - tablets and gel. To be honest, I didn’t expect that with the help of one drug I could completely get rid of large nodes in a vein.

I started therapy - in the morning I took a pill and smeared my legs with gel, and in the evening I applied it again. After the gel was absorbed, I put it on compression stockings(advised by the doctor to increase the therapeutic effect). After a few days, I began to notice that the feeling of heaviness in my legs, pain and swelling began to disappear. The spider veins on my legs gradually disappeared.

Of course, I don’t hope that Phlebodia 600 will completely rid me of the problem of advanced varicose veins, but positive result treatment is obvious. I continue to use the drug according to the course prescribed by the doctor. After another examination, I heard good news - there is no need for surgery anymore!”

Polina, 39 years old, St. Petersburg:“Against the background of varicose veins, I was bothered by pain in my legs, which became simply unbearable. It got to the point that I stopped sleeping at night, it was hard to get out of bed, every step caused extreme discomfort. I got to the clinic, the doctor conducted an examination and prescribed Phlebodia 600 (tablets and gel).

The first course of therapy lasted 3 months, after its completion there was a significant improvement. I even started to walk outside a little, which I had been dreaming about for a long time. Then the doctor prescribed new courses of treatment, with short breaks. As a result, I completed 4 full courses of therapy.

I almost forgot about the pain in my legs and nighttime insomnia. The condition of the veins has improved significantly, I again felt a healthy person. Thanks to the manufacturers for Phlebodia 600! Still, French quality speaks for itself.”

In order to get full help from the drug, it is recommended to use it exclusively as prescribed by a doctor. An experienced specialist will help you choose the right treatment method on an individual basis.

Some features of therapy

During pregnancy and pregnancy, any medications are prescribed with extreme caution. Despite the fact that Fledobia 600 is well tolerated by the body and can cause minimal adverse reactions, it is prescribed only after the examination.

Indications, dosage, risks during pregnancy

Phlebodia 600 during pregnancy is prescribed primarily to relieve swelling in the legs, heaviness and varicose veins, which become frequent companion pregnant women.

When prescribing the drug, preference is given to the gel, which must be applied according to the instructions - in a small amount, with massaging movements, twice a day. Pregnant women have an increased risk of developing allergic reaction on gel.

As for the drug in tablets, it is recommended to prescribe them only in severe cases, in a dosage of no more than 1 tablet per day. At the moment, in clinical practice there have been no cases of severe adverse reactions not described in the instructions. However, taking pills without a doctor's prescription is prohibited. In the second and third trimesters of pregnancy, taking the drug is permissible only if the woman’s health is under serious threat.

Use of the drug during lactation

When breastfeeding, you need to be careful not only with your diet, but also with your medicines. Any substances that enter a woman’s body can be passed on to the baby through mother’s breast milk.

According to experimental studies, the use of Phlebodia 600 during lactation does not have a teratogenic effect on the baby.

However, there is no exact data as to whether the medicinal components of Phlebodia 600 are passed through breast milk to the baby. Therefore, doctors prefer to refrain from prescribing pills to nursing mothers. But therapy can be carried out using a gel.

If, for health reasons, a woman urgently needs to take Phlebodia 600 tablets, breastfeeding must be temporarily suspended (for the period of drug therapy).

Reviews from doctors and patients about treatment during pregnancy

How safe is the use of Phlebodia 600 during pregnancy and lactation, say doctors and their patients:

Samoilova N.I., gynecologist:“Phlebodia 600 is a completely safe remedy. In my practice, there have been no cases where the health of pregnant/lactating women worsened while taking it. Only in rare cases does an allergy occur.”

Karimov A.S., gynecologist:“The drug has a powerful but gentle effect on the body. For this reason, there are no direct contraindications to its use in pregnant and lactating women. However, it is strictly unacceptable to use Phlebodia 600 for self-medication.

A woman’s body during pregnancy and lactation is unpredictable; it is impossible to determine exactly how it will react to even the most harmless natural-based drug. Therefore, the doctor must conduct a detailed examination and assess the risks to the health of the woman and baby before prescribing a therapeutic course.”

Galina, 28 years old, Krasnodar:“While I was carrying the child, spider veins, heaviness in the legs and swelling. The doctor reassured me and said that such changes are quite natural in my situation. I prescribed Phlebodia 600 gel, which I applied morning and evening.

Relief came after the first use! I applied the gel to my legs for two months, which allowed me to feel lightness on my legs. The swelling has gone away, the spider veins have become less noticeable. Separately, I would like to note that I did not find any adverse reactions when using the gel.”

Valeria, 27 years old, Ufa:“After pregnancy, the doctor discovered I had thrombophlebitis. The pathology was on initial stage, so I was prescribed conservative treatment. The doctor prescribed Phlebodia 600 in tablets and also recommended applying the gel to my legs at the same time.

At that time, she was breastfeeding the baby, but the specialist said that breastfeeding would have to be suspended at the time of treatment. I switched the child to infant formula and followed the prescribed treatment (for 3 months). The next examination showed significant improvements. I liked the drug, it allowed me to do without severe invasive or surgical interventions.”

Phlebodia 600 is recognized as one of the safest venoprotectors for female body during pregnancy and lactation. However, you should not self-medicate; therapy should only be prescribed by a specialist. Also, the entire period of treatment must be under medical supervision to avoid the occurrence of negative reactions.

Other indications for the use of tablet and local forms of the drug

The most popular use of Phlebodia 600 is in the treatment of varicose veins. However, the drug is no less effective in the treatment of more specific diseases - prostatitis and hemorrhoids. This is due to the beneficial effect of the active components of Phlebodia 600 on veins and blood vessels, eliminating stagnation of blood and lymph.

Haemorrhoids

For hemorrhoids, Phlebodia 600 improves blood microcirculation and reduces critical lymphatic pressure. When medicinal components enter the body, general metabolic processes improve, and tissues are also saturated with a sufficient amount of oxygen. After the first dose of the drug they decrease inflammatory processes, swelling, eliminated pain syndrome. In addition, it has a powerful venotonic effect.

For the treatment of hemorrhoids, the drug Phlebodia 600 in tablet form is prescribed. Reception regimen:

• the first week of therapy - 3 tablets per day during meals, divided into 3 doses;
• second week – 2 tablets per day (morning and evening) with meals;
• third week - one tablet per day in the morning, with meals.

After completing the prescribed course, the treatment is repeated. The optimal duration of taking tablets is 2 months. If it is necessary to continue treatment, you need to take a break (1 month), after which the patient is prescribed a new therapeutic course according to a similar scheme. At acute form hemorrhoids Phlebodia 600 is not suitable for monotherapy; complex treatment is required.

Prostate inflammation

For prostatitis, Phlebodia 600 is prescribed in tablet form. Depending on the degree of the patient’s disease, 1 or 2 tablets per day are prescribed (after meals). The optimal duration of treatment is 20 days.

According to clinical data, improvement is noted after a week of taking the drug. Swelling is reduced, due to which the size of the prostate gland is normalized, and also eliminated painful syndrome. After completing the full course of therapy, in most cases a complete cure occurs. You may need to take the drug again, but not earlier than in a month.

Reviews from doctors and patients about the treatment of prostatitis and hemorrhoids

To understand whether the drug Phlebodia 600 is actually effective in the treatment of hemorrhoids and prostatitis, it is recommended to read reviews from specialists and patients:

Ardashov P.S., practitioner:“In my opinion, the drug Phlebodia 600 is one of the best in the treatment of hemorrhoidal disease. It is not an expensive pharmacy dummy, but in fact allows you to cope with pathology.

Despite the high therapeutic effect of Phlebodia 600, I prefer to prescribe it in combination with other drugs. Another advantage is the possibility of long-term use of tablets, without the development of addiction, dependence on the drug and the occurrence of severe adverse reactions.”

Efremov I.A., urologist:“Phlebodia 600 is a universal drug that is used not only for pathologies of the veins of the lower extremities, as most consumers believe. The medicine is very successful against hemorrhoids and prostatitis.

Helps increase venous tone, improve blood microcirculation, and has a pronounced antioxidant effect. It acts quickly, a positive therapeutic effect is observed after the first dose of tablets, which has been proven by numerous clinical studies.”

Egor, 43 years old, Vladivostok:“I was prescribed the drug Phlebodia 600 in the complex treatment of congestive prostatitis. The drug was well tolerated, no adverse reactions were noticed. Since my disease was at an advanced stage, I had to undergo a double course of therapy. Repeated examination showed significant improvements. The doctor advised repeating the therapy 3-4 times a year.”

Nikita, 36 years old, Novorossiysk:“I was treated for hemorrhoids, but the drugs prescribed by the doctor did not have the desired effect. I turned to another specialist who prescribed me Phlebodia 600 tablets. I warned the doctor that I had peptic ulcer.

With this diagnosis, many medications (especially in tablets) are prohibited for me. However, the doctor said that Phlebodia 600 is approved for patients with various severe gastrointestinal diseases, and peptic ulcer disease is not a contraindication. I took the pills in a course, the treatment lasted 2 months. As a result, Phlebodia 600 turned out to be the only drug that helped cope with my problem.”

Phlebodia 600 is trusted by doctors and patients, which certainly makes it one of the most popular venoprotectors. Despite all positive sides of this medicine, it is recommended to use it in the treatment of hemorrhoids and prostatitis only as prescribed by a specialist.

Similar funds

Venoprotective drugs are in great demand, so pharmaceutical companies are actively supplying pharmacy chains with new drugs. It is recommended to read the review the best analogues Phlebodia 600.

Russian and imported structural analogues

Experts include the drugs Vasoket, Diovenor 600, Venolek and others as effective structural analogues of Phlebodia 600. General information about the best Russian and imported generics, as well as their cost, is presented in Table. 2. Prices may vary slightly from those shown in the table depending on the region.

Table 2 – Analogues of Phlebodia 600

Drugs from other groups with similar effects

On the shelves of the pharmacy you can find quite a lot of drugs that have an effect similar to Phlebodia. The Top 5 best generics include , and Troxevasin. Brief information and costs of these drugs are presented in Table. 3.

Table 3 - Non-structural analogues

It is important to remember: replacing one drug with another at your own discretion is prohibited! It is necessary to consult with a specialist.

Phlebodia 600 is a high-quality French vein protector, successfully used in the treatment of varicose veins, hemorrhoids and prostatitis. The high cost of the drug is quite justified by its real action and effectiveness. Has a minimum of contraindications and side effects, is well tolerated by the body, so Phlebodia can be prescribed in the treatment of pregnant and lactating women.

Excipients: talc - 10.24 mg, colloidal silicon dioxide - 3.5 mg, stearic acid - 50.05 mg, microcrystalline cellulose - up to 910 mg.

The composition of the film shell: Sepifilm 002 (hypromellose (E 464) - 9.832 mg, microcrystalline cellulose - 7.866 mg, macrogol 8 stearate type 1 - 1.967 mg); Sepispers AP 5523 pink (propylene glycol - traces, hypromellose (E 464) - 0.458 mg, titanium dioxide (E 171) - 4.026 mg, crimson dye [Ponceau 4R] (E 124) - 0.401 mg, iron oxide black (E 172) - 0.13 mg, iron oxide red (E 172) - 0.02 mg); Opaglos 6000 (carnauba wax (E 903) - 0.075 mg, beeswax (E 901) - 0.075 mg, shellac (E 904) - 0.15 mg, ethanol 95° - traces).

15 pcs. - PVC/aluminum blisters (1) - cardboard packs.
15 pcs. - PVC/aluminum blisters (2) - cardboard packs.
15 pcs. - PVC/aluminum blisters (3) - cardboard packs.

pharmachologic effect

Angioprotective agent, bioflavonoid. Has a venotonic effect, improves lymphatic drainage, improves microcirculation, reduces the adhesion of leukocytes to venous wall and their migration into paravenous tissues, improves oxygen diffusion and perfusion in skin tissue, and has an anti-inflammatory effect. Blocks the production of free radicals, the synthesis of prostaglandins and thromboxane.

Pharmacokinetics

Rapidly absorbed from the gastrointestinal tract, detected 2 hours after administration. Cmax in blood plasma is reached 5 hours after administration. It is evenly distributed and accumulates in all layers of the wall of the vena cava and saphenous veins of the lower extremities, and to a lesser extent in the veins of the kidneys, liver, lungs and other tissues. Selective accumulation of diosmin and/or its metabolites in venous vessels reaches a maximum 9 hours after administration and persists for 96 hours. Excreted in urine - 79%, in feces - 11%, in bile - 2.4%.

Indications

Lower extremities, chronic lymphovenous insufficiency of the lower extremities, hemorrhoids, microcirculation disorders.

Contraindications

Children and adolescents up to 18 years of age, first trimester of pregnancy (limited use experience), lactation (breastfeeding), hypersensitivity to diosmin.

Dosage

Taken inside. Depending on the indications daily dose is 600-1800 mg. The duration of use depends on the indications and treatment regimen.

Side effects

From the outside digestive system: often - dyspeptic disorders, incl. nausea, vomiting, diarrhea, heartburn, constipation; infrequently - colitis.

From the side of the central nervous system: rarely - malaise, dizziness.

Allergic reactions: rarely - urticaria; frequency unknown - isolated swelling of the face, lips, eyelids; in exceptional cases - angioedema (Quincke's edema).

special instructions

Pregnancy and lactation

Use is contraindicated in the first trimester of pregnancy (experience of use is limited). Use in the second and third trimesters is possible only as prescribed by a doctor and in cases where the expected benefit of therapy for the mother outweighs the potential risk for the fetus. Use during breastfeeding is not recommended, because... There is no data on the excretion of diosmin in breast milk.

IN experimental studies no teratogenic effect on the fetus was detected.