Ovulation induction drugs. Methods for stimulating ovulation at home Stimulation of ovulation by means

Antipyretics for children are prescribed by a pediatrician. But there are emergency situations for fever when the child needs to be given medicine immediately. Then the parents take responsibility and use antipyretic drugs. What is allowed to give to infants? How can you bring down the temperature in older children? What medicines are the safest?

Increasingly, women are turning to the gynecologist with problems with conception. But medicine does not stand still, it is constantly developing, so the desired pregnancy can occur after treatment with special drugs that stimulate ovulation.

Most often, the inability to become pregnant is associated with the absence of ovulation as such or with its irregular course. There may be several reasons for this:

Diseases of the pelvic organs of an infectious and inflammatory nature (salpingoophoritis, ovaries, etc.).
Too little weight of a woman, usually less than 48 kg, at which there is an insufficient production of sex hormones, which leads to a lack of ovulation and amenorrhea.
Hormonal changes in the body on the background of stress, with excessive weight (when the body mass index is more than 25), with certain diseases thyroid gland(hypo- or hyperthyroidism), etc.
Long-term use of oral contraceptives. In this case, the body ceases to produce hormones on its own, and it sometimes takes several months to fully restore this ability.
excessive physical exercise can also negatively affect ovulation, especially if they are associated with taking synthetic supplements sports nutrition. These drugs have a very negative effect on the female reproductive system.

In what cases is stimulation needed and when it is not carried out

It is possible when a couple cannot conceive a child for a year. If the woman's age is 35+, then this period can be reduced to six months. In any case, a thorough diagnosis is necessary (preferably both partners) to identify the true causes of infertility and make a decision on stimulation.
In particular, the following diagnostic studies are carried out:

Collecting a patient's medical history, which takes into account her age, the presence / absence of abortions and pregnancies, miscarriages, chronic diseases, wearing an intrauterine device, etc.
The patency of the fallopian tubes is checked. For this, non-operative and operational methods are used. The first include metrosalpingography (X-ray examination). A variation is ultrasonic metrosalpingography, when the patency of the tubes is examined with the help of a contrast agent and ultrasound equipment. These methods are not universal, they have their drawbacks, such as the harmfulness of radiation and possible errors in the result. For a more accurate diagnosis, an operational study is used, but giving the most reliable results.
The usual ultrasound examination, which can show possible inflammatory, polycystic, various neoplasms and other pathologies of the female reproductive system.
In some cases, ovulatory failures can occur due to hormonal disorders, so donating blood to determine the amount of female sex hormones is a prerequisite. At the same time, it is recommended to conduct studies of the activity of the thyroid gland, since this organ has a direct impact on female fertility.
The spermogram of the partner should also be carried out, since sometimes the reason for the lack of pregnancy may be insufficient mobility and viability of spermatozoa.
Partner compatibility test. If the results are unfavorable, the doctor may suggest artificial insemination.

It should be noted that contraindications to stimulation are inflammatory diseases of the uterus and (or) ovaries, tubes, adjacent organs and systems (urinary, gastrointestinal tract), hormonal fluctuations, the onset of menopause or the preclimatic period.

After diagnostic measures and in the absence of absolute contraindications, the gynecologist decides on the appointment of drugs that stimulate ovulation.

Ovulation Stimulation Methods

Stimulation of ovulation is possible with the help of drug therapy ( pharmaceutical preparations), as well as using folk recipes and non-traditional therapies.

Pharmaceutical preparations to stimulate ovulation

Vitamins and trace elements

Stimulation of ovulation is impossible without taking vitamin complexes and beneficial trace elements. True "female" vitamins include E, A, B (mandatory folic acid), C. Vitamin D is additionally recommended, especially for women living in areas where sunny days are rare.

Stimulation of follicle maturation with vitamin E

Vitamin A helps follicles and regulates the amount of cervical fluid.
B vitamins are recommended to be taken both at the planning stage of pregnancy and during it, as they not only prolong the luteal phase of the cycle, promote endometrial growth and egg maturation, but also eliminate toxicosis during pregnancy, prevent miscarriages and help healthy development of the fetus.
Vitamin E stimulates maturation, “supports” ovulation itself and increases the production of progesterone, which is especially useful for deficiency of this hormone.
Vitamin C contributes to the normalization hormonal background, and also serves as a means of preventing the development of DNA abnormalities in the unborn fetus.
Also, when preparing for pregnancy, it is advisable to monitor the sufficient intake of Omega-3 polyunsaturated fatty acids into the body. They are found in highest concentrations in fatty fish, synthetic fish oil, as well as in linen and olive oils.
The means to stimulate ovulation also include preparations containing selenium, zinc and iron.

Specialized pills that stimulate ovulation.

Clostilbegit is a drug designed to enhance the maturation of follicles. This effect can cause multiple pregnancy. An interesting fact is that pharmachologic effect The drug has not been fully studied, since it was originally developed as a contraceptive. But the effect turned out to be the opposite, so Clostilbegit is currently successfully used to treat infertility, with both partners.
The drug may not be taken independently, but with auxiliary means. The classic pattern is:

5-9 days of the cycle, 1 tablet of Clostilbegit per day (provided that only one remedy is taken);
if Puregon is prescribed in parallel, then Klostilbegit begins to be taken from the 3rd day of the cycle and ends on the 7th. From the 8th day of the cycle, they begin to drink Puregon. In this case, constant monitoring by ultrasound is necessary. As soon as the follicle reaches 18 mm in diameter, these drugs are canceled and Pregnyl is prescribed, which supports the maturation of the eggs. After that comes auspicious time for conception.

Ovarian stimulation drugs can be taken no more than 5 times in a lifetime to avoid atrophy of the reproductive system.

Gonal-F is a drug that is produced in the form of a powder for injection and is used when planning IVF (in vitro fertilization), as well as when other methods of treatment are ineffective. The drug is administered subcutaneously, the dosage is determined by the doctor individually. Of the pluses, one can single out its effectiveness, of the minuses - the high cost and complexity of application.

Stimulation of ovulation with folk remedies

Simultaneously with drug therapy or as an independent treatment, traditional medicine methods can be used. The most common of these is phytotherapy (herbal treatment).

Sage - used when the lack of ovulation is associated with a lack of estrogen.
Upland uterus - used for lack of progesterone. Prevents miscarriages.
Red brush - can be used simultaneously with sage or hogweed.
Plantain, rose petals, and aloe are also widely used.

The advantages of herbal medicine are relative safety and low cost, the disadvantages are the duration of treatment. It should be remembered that phytotherapy is still a treatment, and herbs are medicines, so a doctor's consultation is required.
More about ovulation stimulation folk methods read .

Alternative therapy

Therapeutic mud also stimulates ovulation, they are recommended in cases where there are diseases of the character. Therapeutic mud relieves inflammation (they are especially effective for chronic diseases), restore impaired reproductive functions.

You can buy such a remedy at a pharmacy, it only needs to be warmed up a little and applied to the stomach at the level of the ovaries. If possible, you can go to a sanatorium specializing in mud therapy, or a suitable resort (for example, Saki).

Stimulation of ovulation with acupuncture is a rather controversial area of medicine, however, there are many cases where the impact on acupuncture points had a positive effect in the treatment of infertility. The complexity of this method lies in the fact that it will take a lot of time to find a professional who specializes in the treatment of female infertility with acupuncture.

All of these methods of restoring ovulatory function are effective. However, they cannot be used randomly. A doctor's consultation is necessary, as well as an extensive and comprehensive diagnosis of both partners.

IN last years anovulation (lack of ovulation) remains a painful topic for many couples. Ovulation induction activities can help many women achieve long-awaited motherhood. Let's talk about who needs ovulation stimulation, how it happens, what drugs to stimulate ovulation can help, well, and when stimulation is undesirable.

Stimulation of ovulation is actively used in modern reproductive medicine. Pregnancy as a result of the procedure occurs in 70% of cases. It should be noted that this method of conception is not suitable for all infertile women.

Stimulation is allowed if normal eggs are formed in the ovaries, but they do not fully mature due to some internal pathologies. It is also recommended to do the procedure for women suffering from polycystic ovaries or having irregular ovulation. But when sick or defective eggs are formed in the ovaries, inflammatory processes in the internal genital organs, hormonal imbalance, ovulation stimulation is not recommended by doctors until other diseases that affect a woman’s fertility are completely cured. Doctors do not allow the procedure to be performed when taking certain potent drugs, as well as to patients in old age.

Stimulation of ovulation allows thousands of women to finally feel what the happiness of motherhood is. Ovulation stimulation is usually prescribed for couples who, during the year, with regular entry into unprotected sexual relations, fail to conceive. If both partners are older than 35 years, then the period for establishing infertility is reduced to six months. Before starting stimulation, a woman needs to go through a fairly extensive medical examination including the following analyses:

for hepatitis;
for syphilis;
for HIV;
for the presence of antibodies to rubella in the blood;
Ultrasound of the state of the mammary glands;
smear for the presence of pathogenic microorganisms;
a smear on foci of inflammation in the uterus and genital tract;
Ultrasound or HSG for the degree of patency of the fallopian tubes.

According to the results of the medical examination, the gynecologist identifies the cause of infertility and makes a conclusion: is the woman capable of becoming pregnant and bearing a healthy and full-fledged child. First of all, the doctor evaluates the patency of the fallopian tubes, because it is through them that the mature egg moves and meets the sperm. If you stimulate ovulation when the tubes are characterized by low patency, then the risk of an ectopic pregnancy increases.

To exclude the possibility of foci of inflammation or injury on the mucous membranes of the uterus, the gynecologist must perform hysteroscopy. Also, a man needs to undergo a medical examination to confirm the viability of his spermatozoa. If a man is infertile, then it is useless for a woman to stimulate ovulation.

What is ovulation stimulation drugs?

Usually, ovulation is stimulated with the help of Clostilbegit, an antiestrogen agent, as well as drugs based on gonadotropins, hormones that regulate functions reproductive organs. The most popular and highly effective drugs are Menopur and Gonal-F.

Stimulant medicines are produced both in tablet form and in the form of ampoules for injection. The dosage and time of administration of the drug is determined only by the attending physician; it is impossible to carry out the stimulation procedure without medical supervision.

All the time while the course of ovulation stimulation lasts, the woman should observe changes in basal temperature and monitor the state of the hormonal background, and the gynecologist should monitor the growth of the follicle and the maturation of the egg in it on the ultrasound machine. Sexual relations during this period must be practiced, if not every day, then at least every other day.

Stimulation of ovulation with drugs is carried out no more than 3-5 times in a lifetime, because with each subsequent procedure, the dose of the active substance increases, which can provoke the extinction of ovarian functions and the premature onset of menopause.

Ovulation stimulation pills

At the initial stage of ovulation stimulation, drugs are used that accelerate the development of the largest follicle in the ovary. There may be several such follicles. Then the patient is given medications that contribute to the rupture of the follicle, the release of the egg from it, and the preparation of the mucous membranes of the uterus for the introduction of the zygote. Most widely used by gynecologists the following drugs stimulating ovulation:

Clostilbegit;
Gonal-F;
Letrozole;
human chorionic gonadotropin;
Dydrogesterone.

How is the stimulation of ovulation with Clostilbegit

Stimulation of ovulation with Klostilbegit is widely used in medicine. The active substance of the drug Clostilbegit, produced in the form of tablets of 50 mg, is clomiphene citrate, which binds estrogen receptors in the hypothalamus. As a result of the action of the drug, there is an excessive formation of follicle-stimulating and luteinizing hormones. Clostilbegit is prescribed mainly to women who have cystic ovarian disease.

The drug should be taken from the second or fifth day of the menstrual cycle. If for some reason a woman has no menstruation for one or more cycles, then the start of the reception can be scheduled on an arbitrary day. Daily dose medication in the first stage of stimulation is 50 mg, the course lasts five days.

If a positive effect does not occur, but you need to proceed to the second stage, in which 100 mg of the stimulant should be consumed within five days. Such treatment is allowed for no more than six menstrual cycles. The maximum amount of the drug consumed should not exceed 150 mg per day. It is worth noting that 85% of women become pregnant four months after the start of taking Klostilbegit.

Approximately 25 - 30% of patients have resistance to the action of the drug. The drug helps women with a low body mass index especially poorly. Medical specialists most often explain the lack of a positive effect by the excessively strong antiestrogenic effect of Clostilbegit, due to which blood circulation in the uterus decreases at the time of the introduction of the zygote, the endometrial maturation process is disrupted, and the amount of cervical fluid secreted decreases. Especially adversely affect the female body high doses of the drug with unreasonably long-term use. Therefore, doctors advise: if fertilization has not happened within four months of taking Klostilbegit, refuse this drug treatment and move on to other methods of stimulation.

Stimulation of ovulation with Gonal-F and Puregon

If the woman's body is resistant to Clostilbegit, the gynecologist may prescribe Gonal-F or its analogue Puregon, a drug that stimulates the pituitary hormone follicles in ampoules for subcutaneous administration. Taking the medication begins on the first day of menstruation or five days after the end of the use of the contraceptive. If there is no menstruation, then treatment is carried out from the day on which she would supposedly have to go. The course of stimulation lasts a week, repeated for six menstrual cycles.

Doctors practice two ways of introducing Gonal-F. With the first method, the dosage of the drug is gradually increased every day. The starting dose for a week is 37 - 50 IU. If the doctor sees on the ultrasound machine that the medicine accelerates the growth and development of follicles in accordance with the norm, then at the end of the week the dosage does not change. If there is no reaction from the follicles, then the volume of the administered medication is increased by 50%. This method of consuming Gonal-F is the most optimal for women suffering from polycystic ovaries, as the doctor can confidently select the required maximum dose of the drug, at which complications are impossible.

The second method of drug administration implies, on the contrary, a gradual decrease in dosage. The starting dose for the first week is very high, 100 - 150 IU. This option of taking Gonal-F is recommended for women over 35 years of age, as well as for irregular periods, small ovarian volume, after surgical intervention on the internal genitalia. However, this method of stimulation is rarely used in practice, since it requires a lot of experience and high qualifications of a medical specialist.

Stimulation of ovulation with Letrozole

Letrozole was originally used to treat menopausal women for breast cancer. Today, the drug is used as a highly effective ovulation stimulator. Often it is prescribed to replace Klostilbegit. The drug is produced in the form of tablets. The stimulation process begins on the third day of the menstrual cycle, the course lasts 5 days. The daily dose is 5 mg, that is, two tablets. The drug has an antiestrogenic effect of medium intensity, helps to increase the synthesis of follicle-stimulating hormone by the pituitary gland, increases the volume and improves the physical condition of the mucous membranes of the uterus. Compared with Clostilbegit, the drug is less powerful, its effect extends for a short time, but side effects are recorded infrequently.

Stimulation of ovulation based on hCG

Stimulants based on chorionic gonadotropin have the action of luteinizing hormone produced by the pituitary gland. Data medicines are used at the second stage of ovulation stimulation, accelerate the process of rupture of the follicle and the release of a mature egg from it, participate in the preparation of the mucous membranes of the uterus for the introduction of the zygote. The most popular and widely used gonadotropin-based drug is Pregnyl, which is available in powder form of various dosages in one package with a solvent for intramuscular injection.

The use of the drug is possible only if the thickness of the endometrium in the uterus is at least 8 mm, and the diameter of the dominant follicle in the ovary reaches at least 18 mm. It is necessary to enter chorionic gonadotropin every three days, 1500 IU. The course lasts 10 days. Ovulation usually occurs two days after drug administration.

Stimulation of ovulation with dydrogesterone

Dydrogesterone is produced in the form of tablets of 10 mg. In pharmacies, it can be found under the name Duphaston. The drug has a progestogenic effect on the uterine mucosa. The stimulant is used in the second half of the menstrual cycle. The daily dose is 20 mg. The duration of the course is at least 18 days. For greater efficiency, the combined use of Dydrogesterone and Pregnil is allowed.

Stimulation of ovulation with vitamins

If a woman wants to get pregnant and give birth to a healthy child, then she must receive a sufficient amount of vitamins and minerals daily. And for this she needs to eat properly and fully. The main vitamin that must be supplied to the body future mother, is B 9 or folic acid. If a pregnant woman is deficient in this substance, then the embryo in her womb runs the risk of acquiring serious pathologies of the physical and mental development. A woman who wants to conceive a child should definitely include cereals, milk and dairy products, eggs, fresh vegetables and fruits, and seeds in her daily diet. It is also recommended to eat foods rich in iodine.

How to stimulate ovulation at home with folk remedies

It is very important to understand that doing experiments on your own, trying to stimulate ovulation, is not advisable. That is, you should not personally install drugs for yourself or use herbal infusions. In the best case, this simply does not lead to anything.

At home, you can apply aromatherapy. It can be used as an additional therapeutic measure. It is not bad to use aromatic oils of lavender and pink geranium - they stabilize the hormonal background and calm the nervous system.

You can include in your menu products that will help stimulate: these are quail eggs, fresh fruits, vegetables, dairy products.

A positive mental attitude is also important. Try not to worry, do not worry because you cannot get pregnant yet. Tune in to the fact that everything will work out, rely on your gynecologist - and the desired pregnancy will finally come.

All other methods of ovulation stimulation must be carried out only under the serious supervision of a specialist, since only a doctor knows how this process should proceed so that it is safe for health.

When is ovulation stimulation contraindicated?

In no case should you engage in stimulation of ovulation on your own whim and without strict control by your doctor. This is a complex and rather dangerous procedure, which should be carried out exclusively for medical reasons. The consequences of improper or excessive stimulation can be dire. If a woman treats the procedure negligently, does not want to undergo an examination and take tests, takes an excessive dose of pills, then by doing so she causes irreparable damage to her own health.

Quite often, overstimulation leads to early exhaustion of the ovaries, and in some cases even rupture. Excessive intake of hormones in the body can provoke the release of several eggs from the ovary at the same time, which inevitably leads to multiple pregnancy with complications. Preparations based on gonadotropins negatively affect the functioning of the thyroid gland, mammary glands and adrenal glands. But a much more terrible consequence of improper stimulation is the so-called hyperstimulation.

This condition is already at an early stage accompanied by severe pain, disruption of the digestive tract, excessive gas formation, vomiting, diarrhea. When the disease reaches a late stage, the pain becomes simply unbearable, a woman accumulates fluid in the pelvis, and sometimes in other organs, and the ovaries grow to unnatural sizes, cysts form on them. A woman has to go to the hospital for a long time, where the fluid is removed through a surgical operation. It's for this reason ovulation stimulation should be performed solely for medical reasons, after checking all the tests and under the strict supervision of the attending physician.

Should I ovulate every cycle? What is pathological anovulation and how is it diagnosed? How to stimulate ovulation with medications and what can be done with "home" methods? These and other questions were answered by Evgenia BROITMAN, obstetrician-gynecologist, head of the IVF department of the AVICENNA Medical Center of the Mother and Child Group of Companies.

What is anovulation?

Lack of ovulation (anovulation) is a violation of the growth and maturation of the follicle, as well as the absence of the release of an egg from the follicle. Such deviations can occur in women, both with a regular cycle and with its failures.

Recall the sequence of the menstrual cycle. It is divided into two phases: follicular and luteal. The first prepares the body for conception, the second - for pregnancy. These phases are controlled by special hormones produced by the pituitary gland - gonadotropins: follicle-stimulating (FSH) and luteinizing (LH) hormones.

The "conductor" of the first phase of the menstrual cycle is FSH. At the beginning of the cycle, the concentration of this hormone is maximum. It stimulates the maturation of the follicle, inside which a young egg is preparing to meet with the sperm. As it matures, the follicle increases in volume and produces an ever-increasing amount of estrogens (including the hormone estradiol). For the pituitary gland, an increase in the concentration of estradiol is like a trigger: it reacts with a strong release of luteinizing hormone. Under the influence of LH, the follicle bursts and ovulation occurs. The residual follicle turns into a corpus luteum and begins to produce progesterone and wait for pregnancy.

Difficulties with ovulation begin with insufficient production of gonadotropins, when the follicle does not mature or there is no egg in the follicle, and also in cases where the egg cannot leave the follicle due to a too dense shell. Unfortunately, anovulation is one of the most common causes of infertility today.

Expert comment

According to statistics, in 30% of cases, the cause of infertility is the absence or irregularity of ovulation. These are data that are recorded in Russia, but they are also confirmed by our foreign colleagues. Therefore, we can say that 30% is a global statistical indicator.

Causes of anovulation

Should ovulation accompany every menstrual cycle? It turns out not! Normally, several cycles a year a woman does without ovulation - the reproductive system arranges for itself a kind of "vacation". The older a woman is, the more often her ovaries strive to rest, so the chances of a quick conception decrease after 35-40 years.

Among the pathological causes of ovulation in the first place are violations in work endocrine system, inflammatory diseases, structural features of organs and stress conditions.

Expert comment

First of all, the reason for the lack of ovulation is hormonal changes. It could be:

violation of the thyroid gland;

dysfunction of the pituitary gland;

improper production of prolactin levels, which leads to an imbalance of the hormones FSH and LH.

In addition, ovulation may be absent due to inflammatory processes in the body.

How is anovulation diagnosed?

It would be misleading to think that the diagnosis of "anovulation" can be made independently on the basis of basal temperature charts or pharmacy ovulation tests. Their results should serve as the basis for contacting a doctor and undergoing a medical examination. It is also impossible to make a diagnosis on one ultrasound - several such procedures will be required.

Expert comment

There are two ways to diagnose anovulation. First, you can conduct a study of the level of progesterone. Secondly, ultrasonic monitoring can be carried out. Usually ultrasound is done 4-5 times during the cycle. This is usually enough to make a diagnosis.

Medical methods of ovulation stimulation

THERE ARE CONTRAINDICATIONS A SPECIALIST CONSULTATION IS REQUIRED

To date, there are four main types of drug stimulation of ovulation:

Antiestrogenic drugs(Klostilbegit, Serofen, Clomid). These drugs in the form of tablets are most often prescribed today, they are the most affordable among ovulation-stimulating drugs. The main effect of these drugs is to increase the level of FSH and LH. However, the appointment of antiestrogenic drugs should be approached with great caution: the slightest violation of the dosage can lead to hyperstimulation, which threatens polycystic ovaries, their depletion and early menopause. In addition, it is recommended to conduct no more than six courses of such therapy in a lifetime. And, therefore, the use of these funds should be carried out under the very strict supervision of a physician.

A milder scheme for influencing the ovaries is considered to be treatment with injections based on human menopausal gonadotropin(for example, Menogon, Pergonal, Menopur). These drugs are synthesized from the urine of menopausal women. They contain the hormones LH and FSH, which are responsible for regulating the menstrual cycle and maturation of the follicles (and therefore help trigger ovulation).

The most effective and safe today are considered recombinant FSH(Puregon, Gonal-F). These drugs are the most expensive. They are received in laboratory conditions by genetic engineering, they are practically devoid of impurities and as close as possible in their action to the natural hormone FSH.

In some cases, injections of drugs containing human chorionic gonadotropin (hCG)(for example, Ovitrel, Pregnil, Horagon, Prophase). Such a drug is used in a situation where the follicles independently mature and develop, but then regress and do not release an egg, as well as in IVF and AI schemes. HCG stimulates the rupture of a mature follicle, which releases an egg ready for fertilization into the fallopian tube.

Important: If you have decided to carry out medical stimulation of ovulation, you need to make sure that your spouse has no problems with conception - current spermogram results are required!

Expert comment

Stimulation can be carried out with antiestrogenic drugs and gonadotropins. Antiestrogenic drugs at one time deservedly received priority, because then there were no good offer by gonadotropins.

Usually, they begin to stimulate ovulation with antiestrogen drugs (if the effect is not obtained, they switch to gonadotropins). Antiestrogen drugs are cheaper than all other stimulation drugs. But they have a number of negative properties. Firstly, they have a negative effect on the endometrium (and when pregnancy occurs, the endometrium should be very good). Antiestrogenic drugs should not be prescribed to women with initially thin endometrium. Secondly, they cannot be used in unlimited quantities - the course can be calculated for a period of 3 to 6 months. Today in our medical center do not use antiestrogen drugs due to side effects.

We conduct stimulation with gonadotropins, hormones FSH, hCG. Preparations are selected individually for each woman. For example, there is an opinion that urinary gonadotropins are more suitable for those patients who are already over 35 years old. In general, gonadotropins are more effective than estrogenic drugs.

HCG injection is done once during stimulation (within one cycle). HCG - included in therapy with gonadotropins (or estrogens).

Home methods to stimulate ovulation

THERE ARE CONTRAINDICATIONS A SPECIALIST CONSULTATION IS REQUIRED

What can you do at home to help your ovaries? We have collected the most popular "home" methods of ovarian stimulation and asked the specialist to comment on them.

Herbs

It is known that many plants contain phytohormones - substances whose action is similar to human hormones. It is these properties of plants that many use in home practice. We have collected several herbs for ovulation stimulation that are most often heard in the recommendations of the "experienced".

Sage (decoction). Sage contains phytoestrogen, a plant-derived substance similar to human estrogen. It is believed that a decoction of sage promotes the formation and growth of follicles, so it is recommended to take it in the first phase of the cycle.

Attention! Sage has many contraindications: it is dangerous for polycystic ovaries, fibroids, endometriosis, pregnancy, lactation.

Linden blossom (decoction). Linden flowers also contain phytoestrogens, therefore, if there are no contraindications, linden tea can also be drunk in the first half of the cycle. Unlike sage tea, which is noticeably knitting, it is also delicious!

Red brush (decoction). This herb is known as "the most feminine" and it is believed that a decoction of it can help restore the balance of estrogen and progesterone - hormones that play an important role in the maturation of follicles, the release of an egg and the further development of pregnancy.

Rose petals (decoction). This is perhaps the most romantic and mysterious way to bring ovulation closer! 1 st. l. rose petals (it is better, of course, to take it from your own garden, and not buy it in a store) you need to pour a glass of boiling water and soak for 15 minutes in a water bath. Ready! Take 1 teaspoon at bedtime for the first half of your cycle. The "magic" properties of this decoction are explained by the high content of vitamin E.

Do not self-medicate - be sure to consult your doctor if you can take this or that decoction - almost all herbs have contraindications.

spa treatments

Healing mud. Mud wraps are a well-known sanatorium method of healing. Therapeutic mud enhances hormonal activity, helps eliminate inflammation and helps restore reproductive functions. Such wraps and mud applications can be done independently at home - after consulting with your doctor, of course.

Baths with kelp. Another pleasant home method, which is very often recommended, without explaining, however, the intricacies of the mechanism of its action, is stimulating baths with kelp. You can buy dry kelp at a pharmacy, steam it well and add the resulting infusion to the bath. Among other things, kelp is also an excellent anti-cellulite remedy - so the benefits are guaranteed!

Diet

To normalize the hormonal background, all means (especially those approved by the doctor) are good! For example, a diet that includes foods that stimulate the production of estrogen. It is worth paying attention to:

pineapples;
soy and legumes;
grenades;
carrot;
pumpkin and sesame seeds;
fatty milk;
spinach;
sprouted wheat.

vitamins

We wrote about the undoubted benefits of vitamins during pregnancy planning in. Taking vitamins such as folic acid, E and C does increase the chances of successful conception. But vitamins are unlikely to help start ovulation in case of serious pathological disorders.

In gynecology, situations are often encountered when a woman cannot conceive due to the lack of ovulatory periods, i.e. due to anovulation. In such clinical cases, it is necessary to stimulate the maturation and release of the egg. There are many methods to stimulate ovulation at home. But the specific choice is determined by the degree of anovulation. In some cases, you can cope with the problem yourself, using home methods, while in others you can not do without medical intervention.

If the patient suffers from anovulation, or the egg rarely matures and leaves the follicle, then stimulation of such a process is shown, thanks to which thousands of patients have already managed to experience the happiness of motherhood.

Usually indications for stimulation are such situations when more than a year of regular sexual intercourse in the absence of protection does not lead to conception.
If the spouses are older than 35 years of age, then the time during which it is not possible to become pregnant is reduced to six months.
Stimulation of ovulation at home and even in the clinic is meaningless if male infertility occurs.
If the patient suffers from tubal obstruction, then stimulation can provoke an ectopic fixation of the embryo. Therefore, patients are advised to undergo laparoscopy first, only after the procedure, in the absence of obstruction, stimulation is allowed.

Methods for stimulating the exit of the female cell

Many women repeatedly ask themselves how to stimulate ovulatory processes and how this can be done. First of all, you need to undergo a thorough examination so that with self-stimulation you do not harm your own health. Home stimulation is a rather difficult task, but with the right approach, it is quite doable.

For stimulation, you can use medications and vitamins, herbs and certain nutrition programs, healing mud or essential oil therapy, etc. More recently, the diagnosis of “female infertility” could destroy the happiness and life of many patients, but with the help of stimulating the maturation and release of the egg, such women appeared real chance.

Such a measure is ideal in the case of polycystic ovarian disease, as well as for patients with a variety of menstrual irregularities, anovulation and other abnormalities. But it should be carried out only after normalization thyroid hormones, androgens and prolactin, otherwise the stimulation will be ineffective. In general, there are many methods, so everyone will be able to choose the most convenient option for themselves. Although any choice should be agreed with the doctor, since only he will be able to choose the most appropriate stimulation option in each individual case.

vitamins for ovulation

One of the effective methods to stimulate ovulation is vitamin therapy. For successful maturation and release of the egg, a woman must have a sufficient supply of trace elements and vitamin substances in her body. To achieve this, you need to provide the diet with the necessary nutrition, correctly compiling the daily menu. To begin with, it is worth enriching the body with folic acid, which is so important that when it is deficient, various intrauterine pathologies occur.

In addition, it is necessary to replenish the required content of potassium iodide, for which iodized salt is included in the diet. If you decide to take complex vitamin preparations, then it is better to choose from those that are recommended for nursing and pregnant women. In the diet, be sure to include as many vegetables, berries, herbs and fruits as possible. These foods are an important stimulating factor for ovulation. It is also recommended to eat more fish, and it is better to refuse black coffee and tea or drink such drinks very rarely. It is imperative to give up unhealthy habits like alcohol or cigarettes, which have an extremely negative effect on the maturation and release of cells.

Medicines

A fairly effective simulation technique is the use of medicines. Stimulate follicular growth can drugs like:

If the follicles grow to the desired size, then the patient may be given injections of human chorionic gonadotropin. They are administered one day after taking the last pill from the above list. The most common hCG injections are Horagon, Profazi or Gonakor. In a day, the ovulatory period should begin.

herbal stimulation

Quite effectively stimulate ovulatory processes medicinal herbs. Stimulation by medicinal plants is carried out in several stages: First, sage is taken, which stimulates follicular formation, then elderflower, which promotes the maturation of the follicle, and then rosemary with plantain, which provokes the activity of the ovulatory period.

Sage contains a lot of phytoestrogen components, which are analogues of female sex hormonal substances. But in order to achieve the desired result, it is necessary to follow the rules of application and dosage. Sage grass is poured into a thermos with a glass of boiling water, tightly closed and kept for about half an hour. Infusion three times a day, use a large spoon. Reception starts from the fifth day of the cycle and is carried out for 1.5-2 weeks, after which it is stopped until the next cycle, starting again after the end of menstruation. Such courses must be repeated at least 3-4 or until conception, if it comes earlier. To enhance the effect, you can add lime blossom (large spoon) to sage, which also contains estrogen-like phytohormones.

Plantain seed is also a highly effective ovulation stimulant. A decoction is prepared from 200 ml of water and 20 g of seeds. The mixture is put on a slow fire and, bringing to a boil, simmer for another five minutes. Then the broth is kept for about 40 minutes, filtered and drunk 30 g before meals. The course of therapy lasts 3 weeks, starting from the first day of the cycle. It would be useful to give this decoction to the future father, especially with possible reproductive problems in a man. Also effective is bathing a woman in a bath with plantain, which is prepared by adding a decoction of 100 g of a mixture of roots and leaves of plantain, filled with boiling water, to the water. Such baths should be taken daily for at least 14 days.

Rose petals rich in tocopherol, which activates ovarian activity, also help well in stimulating the ovulatory period. Therefore, taking a decoction of the petals will only help stimulate ovulation. Fresh petals (20 g) + boiling water (200 ml) are placed in a bath for 20 minutes, then kept for another hour. The tincture is taken daily at night. The duration of therapy is about 4-8 weeks.

diet therapy

A special diet is excellent for ovulatory stimulation. In order for the ovaries to begin to work actively, and the body to intensively produce estrogen hormones, you need to thoroughly approach the preparation of a daily diet. I must have food items like:

Soybeans and beans;
hard cheeses;
Homemade cow's milk and chicken eggs;
Quail eggs;
germinated grains of wheat;
Carrots and apples;
Tomatoes and cucumbers;
Dates and pomegranate;
Flax, sesame and pumpkin seeds.

But there are a number of products that are not recommended for use by women who want to get pregnant. Such products include rice and cabbage, pears, figs, etc.

Essential oils for ovulation

Good stimulating effect essential oils. They can be inhaled, rubbed, most importantly, used regularly. Inhaling the pleasant aromas of basil or anise, sage or cypress, a woman starts intense hormonal production. For convenience, you can use an aroma medallion. Baths with the addition of lavender oil have a positive effect on the hormonal background of patients.

Rose oil, which is used in sitz baths, can also help you get pregnant. 13 drops of oil are added to a basin of warm water. You can use it inside, dropping a drop on tsp. honey or water. Such techniques are performed four times a day.

Mud procedures

A fairly effective and fairly common way to stimulate ovulation is considered to be healing mud, which helps to increase activity. female hormones, eliminates all kinds of inflammation and helps to get pregnant. This procedure is especially recommended for diagnosed ovarian polycystosis. For mud therapy, you need to take pharmacy mud, it is better if it comes from the city of Saki, which is famous for the presence of sanatoriums that relieve women's reproductive problems.

Healing mud is produced in the form of tubes, which must be heated to the required temperature, and then applied with small strokes to the ovarian area, where they are left for half an hour. But before using this method of stimulation, a gynecological consultation is required.

The main stages of stimulation

If Clostilbegit is chosen as a stimulant, then it is taken on the 5th-9th day of the cycle, and Puregon or Menogon begin to drink already from 2 to 10 days. The exact timing should be set by the doctor depending on the situation. When to start stimulation and how long to continue procedures or courses depends on the health of the uterus and ovaries, which is determined by ultrasound examination. The doctor periodically prescribes control ultrasounds to the woman until the follicles grow to 21-25 mm in size. And to avoid the formation of follicular cystic formations or follicular regression, patients are prescribed hCG injections. This procedure contributes to the launch of ovulatory processes.

If everything goes well, then already 1-1.5 days after the chorionic injection, the follicle will burst and the female cell will begin to emerge. If ultrasound diagnostics shows ovulation, then the patient is prescribed injections of Utrozhestan or Progesterone to further support the corpus luteum. When using Klostilbegit, as the patients say, most often it is possible to achieve conception.

Important! The doctor also takes into account the male factor, so he specifies the specific timing and frequency of sexual intimacy in the process of stimulation. With good spermograms after hCG injection, sexual contacts should be carried out every day or a day before the end of the ovulatory period.

If after a three-time application of Clostilbegit positive result cannot be achieved, it is recommended to undergo a more thorough diagnosis and use other therapeutic methods. Before stimulation, the patient must pass laboratory tests for syphilis, HIV and hepatitis, a smear for microflora and oncocytology, ultrasound diagnostics mammary glands, check the patency of the fallopian tubes, etc. The therapist must conclude that the patient is able to bear the child.

Stimulation for in vitro fertilization

If a woman has tube pathologies or ovulatory problems, or her husband does not have enough sperm for conception, then in vitro fertilization becomes a chance for parenthood. With this procedure, the female cell is fertilized in the laboratory, and not inside the body, and then the embryo is placed in the uterus. The method is expensive but effective.

To perform it, the patient is injected with a hormonal stimulator during the period of 19-23 days of the cycle. Under ultrasound control, follicular stimulation is performed, and when the follicle grows to the required size, a puncture is performed and the cell is sent for fertilization. After a few days, the embryo is placed in the uterus, and after a couple of weeks, they check whether the conception has taken place, that is, whether the cell is fixed in the uterine wall. Most often, Clostilbegit is used for stimulation, which effectively stimulates ovarian activity.

Stimulation Contraindications

Not all patients can ovulate. For example, if the female body contains pathological processes that prevent conception and full bearing, then stimulation is not carried out. Such pathologies include adhesions in the tubes, tumors of reproductive structures, etc. In addition, stimulation is not carried out if such a procedure has not given any positive dynamics 6 times before.

Relative contraindications for a stimulating procedure include an age exceeding the 35-year mark. Such a limitation is due to the fact that in such a clinical situation, the probability of having an unhealthy child with a disability or developmental anomalies seriously increases.

Due to environmental degradation, as well as many other negative factors, more and more people come to gynecologists with complaints about the reproductive system. more girls. Fortunately, medicine is developing very rapidly, and now a woman suffering from anovulation is prescribed drugs to stimulate ovulation. She is undergoing treatment, following the recommendations of the attending physician, as a result of which infertility can be overcome.

What is ovulation stimulation

The specialist should determine the need for this procedure. If you have a stable menstrual cycle, and the possibility of getting pregnant exists, you can do without stimulation.

But there are couples who cannot have children. It is in such cases that gynecologists recommend inducing an auspicious day for conception using drugs to improve ovulation or other methods.

The purpose of the process is to provoke the formation of a healthy and full-fledged egg, which will be fertilized by a sperm. To induce a day favorable for fertilization, gynecologists prescribe hormones to stimulate ovulation. The dose that is right for you is determined only by the attending physician, since many features of the body are taken into account.

Why does anovulation occur?

Patients wonder why they can't give birth. The reasons for the lack of ovulation can be as follows:

The girl weighs very little (less than 48 kg). Therefore, the amount of sex hormones is not enough to get pregnant.
Diseases of the pelvic organs, which are infectious and inflammatory in nature.
Oral contraceptives have been taken for too long, and the hormones necessary for fertilization have ceased to be produced.
Strong physical activity and debilitating diets.
Obesity.

There are many external signs that make it possible to determine that you have anovulation:

The nature of menstruation has changed, their number has changed, or they are absent altogether.
The condition of the skin and hair deteriorated.
In the middle of a cycle basal body temperature does not rise.
During the entire menstrual cycle, you observe milky homogeneous discharge.

Ovulation Stimulation Methods

With the help of drugs

Before starting the procedure, both partners undergo a medical examination, that is, tests, as well as studies. It all depends on the age of each of the partners, and on their individual characteristics. Also, the gynecologist takes into account which method you have chosen for conception. There are three of them:

Natural (fertilization of the egg during intercourse).
ICSI (intracytoplasmic sperm injection).
IVF (in vitro fertilization).

The doctor draws up a scheme where the drugs that cause ovulation are indicated, as well as the doses, time and sequence of their use.

The schedule usually looks like this:
5-9 days of the menstrual cycle - Clostilbegit begins to be taken. During the period of taking the tablets, the doctor monitors the development of the follicle. When it reaches 17 mm in size, the doctor prescribes Pregnil. Ovulation occurs after 24 hours. According to statistics, this method helped 15% of girls get pregnant the first time.

ethnoscience

Stimulation with folk remedies is chosen by women who do not want to use medicines once again. If the tests are passed, and the specialist does not see anything wrong with herbal treatment, why not?
Traditional medicine has many recipes that will help conceive a baby.

diet therapy

For a child to be healthy and complete, he needs useful substances. But don't forget about yourself. After all, you have a long process of gestation and childbirth ahead of you. Therefore, the supply of vitamins should be enough for two.

First of all, you need to provide the body with folic acid. It is necessary for the fetus, and if there is a shortage, pathologies may develop.

It is also equally important to consume potassium iodide. It is found in iodized salt.

If you improve your diet with useful products, and remove junk food, the body will become stronger and more resilient.

vitamins

You can drink the complexes that are sold in every pharmacy. It is important that they are of high quality, so if you have any doubts, it is better to choose another manufacturer.

Forget starvation diets. After all, you also need proteins, fats and carbohydrates. Therefore, it is important to eat normally, balanced, eating fruits, vegetables, herbs.

With the help of vitamins, the onset of the luteal phase is regulated, which is fixed after the release of the egg from the follicle.

Women planning to conceive should consume the following items:

C (ascorbic acid);
E (tocopherol);
A (retinol);
B 9 (folic acid);
B 6 (pyridoxine);
D (cholecalciferol);

No need to self-medicate, increase the dose, and reduce it yourself. Stick to the established regimen.

Ovulation stimulation pills

There are various medications to stimulate ovulation. Most often doctors use:
Clostilbegit. Used to increase the chances of motherhood. Active substance- Clomiphene. It activates the production of pituitary hormones, and also affects prolactin, the main task of which is to produce breast milk.

Letrozole. Previously used for the treatment of breast cancer, in the postmenopausal period, but since 2011 it has also been successfully used in the treatment of infertility. The good result is due to the increase

FSH. When it interacts with the reproductive system, there is an increase in the rate of growth and maturation of the follicle. Scientists have proven that this drug is the safest of all available for one simple reason - it is removed from the body before implantation.

Gonadotropins. Gonadotropins are biologically active substances that are produced by the anterior pituitary gland. Gonadotropins include:

Folk remedies

There are many different decoctions, infusions and masks made from natural herbs and plants that help get rid of anovulation. But their influence has not been 100% studied, so it is difficult to argue how much they help to get pregnant, and whether they are better than pills containing chemicals.

Recipes for eliminating female infertility have been kept in people's memory for centuries. They began to be used long before the creation of pills that cause ovulation.

Here are some of these herbs:

sage;
boron uterus;
plantain seeds;
aloe pulp with honey and ghee;

Special gynecological massages, as well as baths with the addition of aromatic oils (rose petals, cypress, lavender, and so on) also have a beneficial effect on improving women's health.

In what cases is the procedure prohibited?

Women with the following diagnoses are not recommended to stimulate ovulation by gynecologists:

obstruction of the fallopian tubes;
ovarian hyperstimulation syndrome;
inflammatory processes in the uterus and ovaries;
sexual infections.

Restrictions on the procedure are set by doctors and according to your age, as well as the state of the body (heart disease, kidney disease, etc.).

The doctor will refer the patient to the following tests:

the presence of antibodies to rubella in the blood;
taking a smear to check the cleanliness of the vagina;
detection of infections (HIV, hepatitis, syphilis);

Negative effects of stimulation

You can call the procedure with drugs no more than 5 times in a lifetime. Otherwise, an early menopause may appear, as well as ovarian exhaustion syndrome, because this is a direct intervention in the human body. There may be bloating, ovarian enlargement, and hot flashes.

Statistics say that 10% of pregnancies that occur in this way are multiple. You may experience:

spontaneous abortion;
early birth;
intrauterine fetal death;

When to expect ovulation and pregnancy

Klostilberg provokes a jump in luteotropin on the 12th-16th day of the menstrual cycle. Although in practice there were often situations when the egg was released on the 11-15th day. The duration of a piece-caused successful period for conception is from 24 to 36 hours.

If the attempt was successful, then after two weeks the first signs will make themselves felt:

fatigue and drowsiness;
unusual eating habits;
instant change of mood: from good to bad;
nausea and vomiting;

These symptoms do not say 100% that conception has occurred, but it is still worth buying a test.

Conclusion

If you have been diagnosed with infertility, this does not mean that you need to stop planning a pregnancy. You still have the opportunity to give birth. Medicine is constantly improving, and gives women who have problems with reproductive organs a huge number of opportunities. These are massages. healing herbs, essential oils, and medications to stimulate ovulation. With a reasonable approach, the likelihood that you yourself will be able to conceive, endure and give birth to a healthy child increases.

Reasons for not ovulating

Most often, the inability to become pregnant is associated with the absence of ovulation as such or with its irregular course. There may be several reasons for this:

Diseases of the pelvic organs of an infectious and inflammatory nature (chronic salpingo-oophoritis, polycystic ovaries, cysts, etc.).
Too little weight of a woman, usually less than 48 kg, at which there is an insufficient production of sex hormones, which leads to a lack of ovulation and amenorrhea.
Hormonal changes in the body due to stress, overweight (when the body mass index is more than 25), with certain thyroid diseases (hypo- or hyperthyroidism), etc.
Long-term use of oral contraceptives. In this case, the body ceases to produce hormones on its own, and it sometimes takes several months to fully restore this ability.
Excessive physical activity can also negatively affect ovulation, especially if it is associated with the use of synthetic sports nutrition supplements. These drugs have a very negative effect on the female reproductive system.

In what cases is stimulation needed and when it is not carried out

Stimulation of ovulation is possible when a couple cannot conceive a child for a year. If the woman's age is 35+, then this period can be reduced to six months. In any case, a thorough diagnosis is necessary (preferably both partners) to identify the true causes of infertility and make a decision on stimulation.
In particular, the following diagnostic studies are carried out:

Collecting a patient's medical history, which takes into account her age, the presence / absence of abortions and pregnancies, miscarriages, chronic diseases, wearing an intrauterine device, etc.
The patency of the fallopian tubes is checked. For this, non-operative and operational methods are used. The first include metrosalpingography (X-ray examination). A variation is ultrasonic metrosalpingography, when the patency of the tubes is examined with the help of a contrast agent and ultrasound equipment. These methods are not universal, they have their drawbacks, such as the harmfulness of radiation and possible errors in the result. For a more accurate diagnosis, laparoscopy is used - an operative study, but giving the most reliable results.
The usual ultrasound examination, which can show possible inflammatory processes, polycystosis, various neoplasms and other pathologies of the female reproductive system.
In some cases, ovulatory failures can occur due to hormonal disorders, so donating blood to determine the amount of female sex hormones is a prerequisite. At the same time, it is recommended to conduct studies of the activity of the thyroid gland, since this organ has a direct impact on female fertility.
The spermogram of the partner should also be carried out, since sometimes the reason for the lack of pregnancy may be insufficient mobility and viability of spermatozoa.
Partner compatibility test. If the results are unfavorable, the doctor may suggest artificial insemination.

Ovulation Stimulation Methods

Stimulation of ovulation is possible with the help of drug therapy (pharmaceutical preparations), as well as using folk recipes and non-traditional methods of treatment.

Pharmaceutical preparations to stimulate ovulation

Vitamins and trace elements

Stimulation of ovulation is impossible without taking vitamin complexes and beneficial trace elements. True “female” vitamins include E, A, B (folic acid is required), C. Vitamin D is also recommended, especially for women living in areas where sunny days are rare.

Stimulation of follicle maturation with vitamin E

Vitamin A helps the maturation of follicles and regulates the amount of cervical fluid.
B vitamins are recommended to be taken both at the planning stage of pregnancy and during it, as they not only prolong the luteal phase of the cycle, promote endometrial growth and egg maturation, but also eliminate toxicosis during pregnancy, prevent miscarriages and help healthy development of the fetus.
Vitamin E stimulates the maturation of the corpus luteum, “supports” ovulation itself and increases the production of progesterone, which is especially useful for deficiency of this hormone.
Vitamin C contributes to the normalization of hormonal levels, and also serves as a means of preventing the development of DNA abnormalities in the unborn fetus.
Also, when preparing for pregnancy, it is advisable to monitor the sufficient intake of Omega-3 polyunsaturated fatty acids into the body. They are found in highest concentrations in fatty fish, synthetic fish oils, and linseed and olive oils.
The means to stimulate ovulation also include preparations containing selenium, zinc and iron.

Specialized pills that stimulate ovulation.

Clostilbegit is a drug designed to enhance the maturation of follicles. This effect can cause multiple pregnancy. An interesting fact is that the pharmacological action of the drug has not been fully studied, since it was originally developed as a contraceptive. But the effect turned out to be the opposite, so Clostilbegit is currently successfully used to treat infertility, with both partners.
The drug may not be taken independently, but with auxiliary means. The classic pattern is:

5-9 days of the cycle, 1 tablet of Clostilbegit per day (provided that only one remedy is taken);
if Puregon is prescribed in parallel, then Klostilbegit begins to be taken from the 3rd day of the cycle and ends on the 7th. From the 8th day of the cycle, they begin to drink Puregon. In this case, constant monitoring by ultrasound is necessary. As soon as the follicle reaches 18 mm in diameter, these drugs are canceled and Pregnyl is prescribed, which supports the maturation of the eggs. After that, there comes a favorable time for conception.

Stimulation of ovulation with folk remedies

Simultaneously with drug therapy or as an independent treatment, traditional medicine methods can be used. The most common of these is phytotherapy (herbal treatment).

Sage - used when the lack of ovulation is associated with a lack of estrogen.
Upland uterus - used for lack of progesterone. Prevents miscarriages.
Red brush - can be used simultaneously with sage or hogweed.
Plantain, rose petals, and aloe are also widely used.

The advantages of herbal medicine are relative safety and low cost, the disadvantages are the duration of treatment. It should be remembered that phytotherapy is still a treatment, and herbs are medicines, so a doctor's consultation is required.
Read more about ovulation stimulation with folk methods HERE.

Alternative therapy

Therapeutic mud also stimulates ovulation, they are recommended in cases where inflammatory diseases are present. Therapeutic muds relieve inflammation (they are especially effective in chronic diseases), restore impaired reproductive functions.

Stimulation of ovulation with acupuncture is a rather controversial area of medicine, however, there are many cases where the impact on acupuncture points had a positive effect in the treatment of infertility. The complexity of this method lies in the fact that it will take a lot of time to find a professional who specializes in the treatment of female infertility with acupuncture.

Ovulation is the natural process of the release of an egg into the fallopian tube after the rupture of a mature follicle. Usually occurs 14 days before the onset of menstruation. For a number of reasons, the egg may not be released from the follicle. In this case, artificial stimulation of ovulation is required. Experts at the IVF Reproductive Health Clinic use dozens of techniques aimed at maturation of the follicle and the release of the egg into the fallopian tube. Doctors prescribe medications (Klostilbegit, Letrozole, gonadotropins, Dydrogesterone, etc.), select a diet, eliminate hormonal imbalances, and give recommendations for lifestyle correction. As a result complex therapy a woman ovulates, which is necessary for the conception of a child.

Features of the ovulatory phase

In healthy women, the rupture of the follicle with the further release of the egg into the fallopian tube occurs without stimulation approximately 14 days before the onset of menstruation (with a 28-day cycle). Small deviations from the average are often observed and are considered the norm.

On the eve of ovulation, the ovarian follicle increases in size up to 2 cm in diameter. At this point, an egg matures in it. Under the action of hormones, a rupture appears in the follicle. Through it, the egg enters the oviduct (fallopian tube), and then into the uterus, where fertilization takes place. The duration of the entire process does not exceed 48 hours. However, many women of reproductive age have irregularities in the ovulation phase. This leads to difficulties in conceiving a child.

Indications for the procedure

Doctors at the IVF Reproductive Health Clinic prescribe ovulation stimulation after laboratory and instrumental diagnostics. Therapy is indicated for women who have been diagnosed with anovulation caused by:

polycystic ovaries;
hyperandrogenism;
resistant ovary syndrome;
hormonal disorders in diseases of the endocrine system;
hypothalamic-pituitary dysfunction;
pathologies of the reproductive system from prolonged use of contraceptives and hormonal drugs.

Stimulation of ovulation is shown after undergoing a comprehensive diagnosis, which is aimed at detecting the cause of deviations in the menstrual cycle.

Preparation for the procedure

Before stimulating ovulation, it is necessary to undergo a clinical diagnosis. First of all, a woman is prescribed a laboratory test. These include:

analysis of venous blood to detect antibodies to pathogens of syphilis, immunodeficiency virus, toxoplasmosis, chlamydia, cytomegalovirus, rubella;
urine culture for the diagnosis of trichomoniasis and vaginal candidiasis;
a smear from the vagina to detect mycoplasmosis, gardnerella, pathologically altered cells;
urinalysis to determine the indicators of prolactin, estrogen, testosterone.

Instrumental diagnostics is also shown. Patients are referred to:

general examination by a therapist;
examination by a gynecologist;
ECG (under stress and in a relaxed state);
Ultrasound of the pelvic organs - the method helps to detect organic pathologies, malignant and benign tumors;
x-ray of the fallopian tubes - necessary for the diagnosis of obstruction;
folliculometry - this method ultrasound allows you to track the growth and development of follicles in dynamics.

The doctors of the IVF Reproductive Health Clinic select the treatment individually, depending on the reasons that caused the abnormal course of the menstrual cycle.

What is ovulation induction

This is a procedure in which experts artificially stimulate the maturation of eggs. During induction in the follicles of a woman, both one and several cells can develop. Similar treatment should be carried out with IVF or insemination. The more mature eggs a reproductologist extracts from a woman's ovaries, the higher the chance for a successful outcome of in vitro fertilization. Induction can be carried out with medications.

Methods of artificial stimulation

In medical practice, there are many ways to speed up the process of maturation of the egg and follicle. Particularly effective are:

drug therapy - involves the appointment of drugs that normalize the production of female hormones that restore the menstrual cycle;
diet - nutrition correction helps to restore metabolic processes, increase the supporting forces of the body;
vitamin therapy - is aimed at eliminating the deficiency of vitamins (A, D, C, E, etc.), as well as macro- and microelements (iron, zinc, calcium, phosphorus).

Stimulating the ovulation process in several ways at once increases the chances of restoring the menstrual cycle and further conceiving a child.

Medical treatment

When pathologies are detected in the maturation of follicles and eggs, specialists use drugs to stimulate ovulation. Means are selected taking into account the age and weight of the patient, as well as the cause of the violation. In addition, the choice of a specific drug depends on the further method of egg fertilization (natural, IVF, ICSI, IMSI, etc.).

The medicine prescribed to stimulate ovulation does not give the result immediately. Only 15% manage to get pregnant after a short course of medication. Specialists of the IVF clinic psychologically prepare women, introduce them to statistics in order to reduce stress in case of a failed attempt.

List of effective drugs

In medical practice use dozens of drugs that can stimulate the maturation of the egg. The safest and most effective of them are:

Clostilbegit is a drug that increases the production of luteinizing (LH) and follicle-stimulating (FS) hormones. It is applied from the 2nd day of the cycle once a day. The total duration of treatment reaches 5 days. One tablet of the product contains 50 mg of clomiphene citrate.

"Letrozole" is a hormonal drug with a minimum list of contraindications. Produced in the form of film-coated tablets. The remedy is used from the 3rd day of the menstrual cycle, 1 capsule for 5 days.

"Dufaston" ("Dydrogesterone") - with a moderate intake of the drug, an increase in the concentration of the hormone progesterone in a woman's body occurs. Thanks to this, the ovulatory phase is normalized. "Dufaston" take 1-2 tablets twice a day. The duration of the therapeutic course reaches an average of 18 days. After taking it, it is recommended to do an ultrasound to confirm pregnancy.

"Ovariamin" is a dietary supplement, it is not medication. Many experts prescribe it because of the high content of cytamine in the preparation. This active ingredient has a beneficial effect on the functioning of the ovaries.

"Cyclodinone" is a medicine produced in the form of tablets. It is prescribed after ovulation to support the formation of the corpus luteum in the ovary. The drug normalizes the index of follicle-stimulating hormone in relation to luteinizing. It is prescribed for the detection of prolactin deficiency.

Vitamins to stimulate ovulation

One of the reasons for the disruption of hormone production lies in the deficiency useful substances, macro- and microelements in the body. In this case, vitamin therapy is used to stimulate ovulation. of greatest importance for female body has folic acid. Lack of vitamin B9 can lead to difficulties not only during conception, but also when carrying a child.

For successful fertilization, vitamins are of particular importance:

A - promotes tissue regeneration, slows down the aging process;
C - affects the synthesis of hormones, increases the body's defenses;
B12 - normalizes fat metabolism, lowers blood cholesterol (assigned to overweight women);
E - slows down the aging process, participates in the synthesis of female hormones, improves soft tissue regeneration, lowers blood pressure.

Vitamins can be used separately, but for the purpose of prevention, experts prescribe complexes. These include drugs of the type "Aevit", "Pikovit", "Complivit", Centrum, Vitrum and others. Vitamin complexes selected individually, taking into account the state of health.

Nutrition for Successful Ovulation

Food is the main source of nutrients, macro- and microelements. The diet significantly affects the menstrual cycle and the ability to conceive. Women who consume a lot of fats and carbohydrates may suffer from overweight, high cholesterol, diabetes. Such diseases adversely affect the functioning of the reproductive system. A lack of body weight is also dangerous - the concentration of female hormones (estrogen, progesterone, prolactin, etc.) decreases in the body.

Specialists appoint proper nutrition to stimulate ovulation, recommending to include in the menu:

fermented milk products (cottage cheese, hard cheeses, milk);
fruits / vegetables rich in fiber, trace elements and vitamins;
germinated wheat;
legumes (chickpeas, beans, peas);
quail eggs;
walnuts;
flax, sesame and pumpkin seeds;
dates.

In the process of treatment, it is necessary to stop drinking alcohol and smoking. Allergies may occur to certain foods prescribed by the diet. To prevent its occurrence, it is recommended to pre-pass allergy tests.

Stimulation of ovulation at home

You can normalize the work of the reproductive system with folk remedies. Decoctions on various herbs to increase female fertility are not recommended for use during menstruation. The course of treatment should not exceed 3 months.

The greatest effect on the reproductive system of women has a decoction of sage, which stimulates the production of estrogen. For medicinal purposes, dry leaves of the plant are used: one tablespoon is poured with boiling water, infused for 40 minutes. The decoction should be taken one sip several times a day.

For the purpose of prevention inflammatory diseases the genitourinary system is used infusion of rose petals. To make a decoction, pour two tablespoons of the crushed plant with boiling water, leave for 5 minutes.

In diseases of the reproductive system, psyllium seeds are indicated. They slow down the aging process in the body, have anti-inflammatory, bactericidal, immunostimulating effects.

Important! Stimulation of ovulation with the help of traditional medicine should occur with the permission of the attending physician. The specialist will select the optimal dosage, taking into account the patient's state of health, her weight and age.

Stimulation of ovulation during IVF

The procedure for accelerating the maturation of the egg during artificial insemination is carried out in two cases: if the patient has the fallopian tubes removed or her partner has a pathology of spermatogenesis. If a woman is prescribed ovulation stimulation before IVF, doctors select a short or long protocol. In the first case, specialists carry out the procedure from the beginning of the menstrual cycle, in the second, they perform preliminary training before medical procedures.

When the follicles reach the desired size, doctors puncture the egg. The selected material is fertilized artificially in the laboratory. After 3–5 days, the embryo is implanted into the prepared uterus. After 2-3 weeks, the patient is prescribed a control ultrasound to confirm pregnancy.

Stimulation of the ovulatory phase in polycystic ovaries

To diagnose the disease, it is necessary to do a blood test to check the concentration of testosterone and insulin (in case of violations, the indicators are increased). You should also undergo an ultrasound, which will show an increase in the ovaries by 1.5–2 times.

By stimulating ovulation in PCOS (Stein-Leventhal syndrome), specialists use the hormone therapy method necessary to reduce the concentration of testosterone in the patient's body. In this case, medicines containing metformin or clomiphene citrate are prescribed. The result of the therapy can be expected after 2-3 months.

Stimulation of the ovulatory phase in multifollicular ovaries

In some cases, 7-8 follicles with a diameter of 4 to 10 mm can simultaneously form in the ovaries. In this condition, the indicators of luteinizing hormone, insulin and testosterone are normal, so the woman is ready to conceive without additional hormone therapy. With multifollicular ovaries, a multiple pregnancy is formed. This feature is taken into account when choosing a specific method of ovulation stimulation.

Pregnancy after the procedure

Only 15% of patients, after undergoing one course of treatment, manage to conceive a child. However, the restructuring of the reproductive system is a complex and lengthy process. With the selection of adequate drug therapy and diet, women still become mothers. The main thing is not to give up and continue treatment.

Pregnancy of women who have undergone stimulation takes place under the constant supervision of a doctor. The specialist prescribes frequent instrumental and laboratory examinations (including blood donation for hormones). Diagnostics helps to timely identify fetal hypoxia, fading and other pathologies.

Contraindications and side effects

Specialists do not prescribe procedures only in individual cases. Stimulation is a contraindicated method if:

infertility is caused by diseases of the male reproductive system;
a woman was diagnosed with uterine pathology (neoplasm, deformity, etc.);
the patient was diagnosed with obstruction of the fallopian tubes;
the woman is 35 years of age or older.

Despite the use modern methods treatment, complications may occur after stimulation of the ovulatory phase. Side effects appear in the form:

hyperhidrosis (excessive sweating);
hot flashes;
ovarian enlargement;
flatulence;
headaches;
menstrual irregularities (delays);
multiple pregnancy;
ectopic pregnancy;
spontaneous abortion.

Treatment under the constant supervision of a doctor, compliance with the requirements for taking medications, systematic examinations reduce the risk of complications.

Conclusion

If the patient is diagnosed with a violation of the ovulatory process, it is necessary to find the cause that caused this condition. Only after that, experts can start the selection effective treatment. In severe clinical cases, it may take several months to restore the ovulatory phase.

To hormone therapy gave the result, patients need to be treated by experienced professionals who have positive reviews About work. Such doctors are doctors of the IVF Reproductive Health Clinic. Specialists have been practicing medicine for over 15 years, constantly improving their skills at Russian and international conferences.