Janine or regulon which is better. The use of hormonal drugs for endometriosis

Antipyretics for children are prescribed by a pediatrician. But there are emergency situations with fever when the child needs to be given medicine immediately. Then the parents take responsibility and use antipyretic drugs. What is allowed to be given to infants? How can you lower the temperature in older children? What medications are the safest?

Hormonal medications for endometriosis are the most important component that is necessarily included in the treatment plan for this pathology. This is because hormones and endometriosis are interconnected. Currently, hormonal therapy is considered the most optimal, allowing to eliminate the disease, but at the same time preserve the function of childbearing.

What is the essence of hormone treatment?

Due to the fact that the main cause of this disease is a hormonal imbalance in a woman’s body, therapy with hormonal drugs helps normalize it, resulting in the elimination of the symptoms of the pathology.

Hormones for endometriosis are used to artificially stop menstruation for a certain period of time. This is necessary because it is during menstruation that endometrial cells begin to bleed intensely. By stopping menstruation, the cells will remain at rest and can be more easily removed.

Progestins also affect the body in such a way that the level of female sex hormones, estrogen, decreases, which is maintained for some time. In addition, these drugs block the further development of the disease, eliminate pain syndrome and bleeding from the uterus.

Treatment with hormones for endometriosis is effective, but mainly only for initial stage. If the disease is severe, then the drug method does not always produce the desired effect. But still, such drugs are used as auxiliary drugs.

Utrozhestan for the treatment of pathology

Utrozhestan for endometriosis is quite effective remedy, which is created on the basis of estrogen. As a result of its use, the patient normalizes secretory transformation in the tissues of the uterus. The medicine is recommended to eliminate progesterone deficiency. The drug helps fight the growth of the endometrium in the uterus.

The attending physician independently prescribes the dosage and duration of therapy with this drug. Usually, when a woman has a progesterone deficiency, 200-300 mg of medication per day is prescribed, half should be taken in the morning and half in the evening.

The use of a hormonal drug for endometriosis may cause some adverse reactions. These include bleeding, dizziness, and a tendency to sleep. It is not recommended to take it if a woman has bleeding, has had an incomplete abortion, is predisposed to the formation of blood clots, and also if the patient is allergic to the active component of the drug. In addition, Utrozhestan is not prescribed if a malignant neoplasm that has arisen in the genital organs or a malfunction of the liver is detected.


Janine in the treatment of the disease

Used for adenomyosis and Janine. This drug is an oral contraceptive (COC). It is also based on estrogens and gestagens. Its main purpose is contraception, and in the treatment of endometrial proliferation it is used as a component complex therapy hormones, helping to slow down the development of pathology.

How much Janine should drink is determined by the doctor. You should not take it on your own. Otherwise, unpleasant consequences may occur. The patient may notice that her mammary glands have become enlarged, began to ache, secrete some kind of fluid, and may also experience heavy bleeding from the uterus, disruptions in the functioning of the digestive and reproductive systems, allergies, weight gain, etc.

Such progestins are prohibited from being consumed by those who suffer from thrombosis, have had heart attacks and strokes, suffer from migraines, nervous pathologies, problems with the liver, kidneys, diabetes mellitus, pancreatitis and malignant neoplasms. It is also not recommended for women who are pregnant and breastfeeding to take it.

Regulon as a remedy against endometriosis

For endometriosis, a contraceptive such as Regulon is also used. When taking it, ovulation becomes more difficult, the viscosity of the cervical secretions increases, as a result of which sperm cannot penetrate the uterine cavity. The amount of blood and pain during menstruation also decreases.

Regulon is used as prescribed by your doctor and should be taken according to his recommendations. It is used mainly after 40 years, when the issue of having children has already been resolved. It helps prevent unwanted conception.


The drug Qlaira for the treatment of the disease

Qlaira and Regulon are similar to each other; they are both oral contraceptives (COCs) that inhibit ovulation. In the treatment of endometriosis, it can reduce the sensitivity of the endometrium, reduce bleeding during menstruation, eliminate pain, and prevent the development of gynecological diseases.

Carrying out hormone therapy for endometriosis, this medication is well tolerated by most women with different ages. It is used as a component of a comprehensive plan for the treatment of endometrial hyperplasia with hormones. It is necessary to drink Qlaira in accordance with the recommendations of a specialist. Doctors advise taking the tablet with plenty of water and taking it regardless of when you had a meal. However, it is recommended to take the medicine exactly at the same time.

If the dosage and other advice of the attending physician are not followed, adverse reactions may occur:

  • varicose veins;
  • blood clot formation;
  • blood pressure problems;
  • disruptions in operations digestive system;
  • headache;
  • allergy.

It is not recommended to prescribe such contraceptives to women who have individual intolerance to the active substance of the drug, lactase deficiency, a tendency to form blood clots, problems with the functioning of the heart and blood vessels, or diabetes.

Patients who have been diagnosed with liver pathologies and malignant neoplasms should take the drug with particular caution. Just like Regulon, Qlaira is not used for endometriosis by women who are expecting a child, are breastfeeding, suffer from vaginal bleeding, or by patients under the age of majority.


Mirena spiral and Nuvaring ring in the treatment of pathology

Mirena is a special treatment system that is installed inside the uterine cavity. It has a progestational effect, releasing levonorgestrel into the uterus. This substance helps reduce the sensitivity of the endometrium to estrogen and progesterone.

It is used both for hormone therapy for endometriosis and as a prophylaxis for any endometrial diseases. The system is introduced into the uterine cavity, it removes the active substance at a rate of 20 mg per day. After using it for 5 years, the medicine begins to release more slowly, up to only 10 mg per day.

The main purpose of the contraceptive is to prevent conception, and in case of endometriosis it is used as replacement therapy estrogens. It is not recommended for use by patients who are in an interesting position, suffering from inflammatory processes in the pelvic organs, malignant or benign tumor uterine cavity, bleeding, liver problems and allergies to the active substance of the drug.


The Mirena spiral for endometriosis remains effective for 5 years, after which it is removed. The system is installed in patients undergoing hormone replacement treatment along with transdermal or oral estrogen. It can be purchased only upon presentation of a prescription from the attending physician.

Before a specialist installs Mirena for endometriosis, it is very important to undergo an examination to be sure that there are no pathological processes in the endometrium. It is worth noting that in the first months of using the coil, bleeding or slight bleeding may occur.

The Nuvaring ring is also inserted into the vagina once a month. It must remain there for 21 days, after which it must be removed. After a pause for a week, it is installed again. Bleeding may occur for 2-3 days after the ring is removed, which is due to the fact that the medicine has stopped working.


Yarina as a cure for endometriosis

Yarina is used as a hormonal treatment for endometriosis. The main purpose of the drug is to prevent unwanted conception, which is why it is classified as an oral contraceptive. COOK. It also helps patients who suffer from acne and fluid retention in the body, which is of a hormonal nature.

The attending physician himself determines how much the patient needs to consume and how long the course of therapy should last in a particular case. The treatment regimen is selected strictly individually for each patient. Typically, Yarina is recommended for women over forty years of age to take it for six months.

If used incorrectly medicine Negative side effects may occur:

  • pain and discharge from the mammary glands;
  • headache;
  • pathologies of the digestive system;
  • changes in vaginal discharge;
  • body weight gain;
  • allergic reaction to the active component of the drug.

Contraindications to taking Yarina for endometriosis are factors such as the presence of thrombosis, diabetes mellitus, liver disease, malignant neoplasms of the reproductive system, vaginal bleeding and intolerance to the drug substances.


Jess in pathology therapy

Jess is a new medication that includes a minimal amount of hormones. It is used in complex therapy of endometriosis, suppresses ovulation, and makes the cervical substance more viscous.

Jess also helps the patient’s menstrual cycle change in the direction of increasing or decreasing, eliminating the pain that a woman experiences during menstruation. When taking the drug, it is possible that the girl will begin to lose weight, this will indicate the effect of the drug.

Jess will help eliminate peripheral swelling, improve facial skin, get rid of acne, and strengthen hair. Such positive changes occur due to the fact that female body drospirenone affects. Jess is taken according to the doctor’s recommendations, the main one of which is to use the drug every day at a specific time.


Medicine "Silhouette" in the treatment of illness

Silhouette medications for endometriosis, like Jess, are used as part of a comprehensive hormonal treatment plan. COCs have a good antiandrogenic effect. The use of this drug allows you to prevent ovulation, make cervical mucus more viscous, change the peristalsis of the uterine tubes, and transform the structure of the endometrium.

The active substances of this medication act in such a way that the androgen content in a woman’s plasma decreases. When using the product, you should adhere to the specialist’s recommendations, which are that the patient should drink Silhouette daily and strictly at a certain time.

Otherwise, you may encounter consequences such as a malfunction of the digestive system, varicose veins, migraines, weight loss or gain, allergies, disorders nervous system, bleeding from the vagina, pain in the mammary glands.


Which of the birth control pills for endometriosis is better to choose - Qlaira or Janine, Regulon or Silhouette, Nuvaring ring or Mirena? Only a doctor can say this, based on the individual characteristics of the patients.

The use of hormonal treatment for endometriosis has a positive therapeutic effect, but the prognosis for recovery can only be favorable when treating the initial stage of the disease. In advanced forms, hormonal medications may not help. Therefore, it is very important to consult a doctor promptly if there are suspicions and signs of pathology development, and to treat it.

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

Lyudmila asks:

How to choose oral contraceptives?

To choose oral contraceptives correctly, it is necessary, firstly, to find out which gynecological and somatic diseases this woman has. If a woman is breastfeeding or has contraindications to the use of combined oral contraceptives (for example, diabetes mellitus, hypertension, thrombophlebitis, etc.), then she should opt for drugs from the mini-pill group. In this case, she can take any contraceptive from the mini-pill group, for example, Charozetta, Microlut, Ovret, Micronor, Lactinet, Exluton.

If a woman has no contraindications to taking combined oral contraceptives, then the optimal drug should be selected from this group. It is best to start selecting an oral contraceptive with a monophasic low-dose or micro-dose drug that contains less than 35 mcg of estrogen and a low-androgenic progestogen (norgestrel, levonorgestrel, gestodene, desogestrel, norgestimate, medroxyprogesterone, cyproterone, dienogest, drospirenone or chlormadinone). Monophasic low-dose and micro-dose drugs, which should be used to begin the selection of the optimal oral contraceptive, include the following:

  • Belara;


  • Jess Plus;

  • Diana-35;

  • Dimia;






  • Midiana;


  • Miniziston;




  • Silest;

  • Silhouette;

  • Femoden;

In order to choose the optimal oral contraceptive for a given woman among the above, it is necessary to find out what gynecological problems she has. So, for various menstrual irregularities or dysfunctional uterine bleeding It is recommended to use contraceptives with strong gestagen effects, such as Marvelon, Microgynon, Femoden or Janine. For endometriosis Women are recommended drugs containing the following gestagenic components:
  • Dienogest (Silhouette, Janine);

  • Levonorgestrel (Rigevidon, Microgynon, Miniziston);

  • Desogestrel (Marvelon, Regulon, Mercilon, Novinet);

  • Gestoden (Femoden, Lindinet, Logest).
Women who have diabetes or smoke, should take oral contraceptives with a maximum estrogen content of 20 mcg, such as Jess, Dimia, Miniziston, Lindinet, Logest, Novinet, Mercilon. If oral contraceptives cause weight gain and severe swelling, then you should switch to taking Yarina.

If, while using monophasic contraceptives, symptoms of estrogen deficiency are observed, such as irregular menstrual cycle, vaginal dryness, decreased libido, then you should switch to three-phase birth control pills, such as Qlaira or Tri-Mercy.

During the first three months of using oral contraceptives, a woman may experience side effects, since there is a period of adaptation of the body to a new mode of functioning. If after 3-4 months the side effects do not go away on their own, then the oral contraceptive should be changed.

The oral contraceptive should be changed taking into account what specific side effects the woman has developed. Currently, the following recommendations have been developed for replacing oral contraceptives based on what side effects the drug caused in a woman:

  • Decreased libido, scanty menstruation, intermenstrual bleeding at the beginning and middle of the cycle or depression - you should switch to triphasic contraceptives (Qlaira or Tri-Mercy) or to drugs containing at least 30 mcg of ethinyl estradiol (Yarina, Midiana, Lindinet, Femoden, Silest , Zhanin, Siluet, Miniziston, Regulon, Marvelon, Mikroginon, Rigevidon, Belara);

  • Acne - you should switch to contraceptives containing gestagens with an antiandrogenic effect, such as Diane-35, Jess, Yarina, Chloe, Janine, Siluet, Dimia, Midiana, Belara;

  • Breast engorgement - you should switch to single-phase contraceptives containing 20 mcg ethinyl estradiol and drospirenone, such as Jess or Dimia;

  • Vaginal dryness - you should switch to three-phase contraceptives (Tri-Mercy or Qlaira) or to drugs with another progestogen

Hormonal contraception for women is one of the most popular and reliable, because it is easy to take, treats many gynecological diseases, balances hormonal levels, and does not require the additional use of barrier methods of contraception. Despite all the advantages, you should not select oral contraceptives on your own without medical assistance, because they contain synthetic hormones, and the incorrect use of which will cause many side effects. There are also certain contraindications to taking hormonal contraceptives, so self-medication in this matter is life-threatening.

The most famous trade names Among the means of hormonal contraception are monophasic low-dose drugs - regulon and. Many girls and women are concerned about the question: is it better to choose Yarina or be treated with Regulon?

Comparison of medications and which one is better

What Regulon and Yarina have in common is that these drugs are taken for 3 weeks in a row with a week break for menstrual bleeding, and the amount active ingredients they do not change depending on the phase of the monthly cycle, if compared by duration of use. Yarine and Regulone also have a common active component - ethinyl estradiol in an amount of 30 mcg per tablet.

The main difference between the medications is the gestagen component. If in Yarina it is drospirenone - a third generation antiandrogenic gestagen with an antimineralocorticoid effect, then Regulon belongs to older hormonal contraceptives, but also of the third generation, because it contains desogestrel, a derivative of levonorgestrel.

The main misconception is that if the medicine is more modern, then it will be equally well tolerated by all women, which is fundamentally wrong. Each female body is unique, and depending on specific morphological characteristics, will respond to different hormonal agents individually. For this reason, it is impossible to answer the question - what is better to choose - regulon or yarina, because for some girls yarina is ideal, and for others the old proven regulon.

Brief characteristics of gestagens in preparations

If you carefully study the gestagenic properties of each drug, you can find many differences. Desogestrel has strong gestagenic properties, which has a pronounced contraceptive effect, it has virtually no androgenic effect, and does not exhibit antiandrogenic and antimineralocorticoid properties, which makes it quite neutral. One tablet contains 150 mcg of desogestel. If you choose a drug according to female phenotypes (there are only three of them - estrogenic, balanced and gestagenic), then Regulon is best suited for women of the estrogenic type who do not suffer from swelling, acne and hair loss, but have a tendency to have low progesterone in the body. This medication can also be taken by girls with a balanced phenotype.

Drospirenone differs significantly in pharmacological properties from desogestrel. Drospirenone has weaker gestagenic properties and does not have androgenic effects, exhibits antiandrogenic properties. Drospirenone is also characterized by pronounced antimineralocorticoid properties, which allows it to be used by women suffering from increased swelling. Yarina is ideal for women with oily skin, dark hairs in unwanted places and acne. The presence of androgenic properties in a contraceptive is a disadvantage, since such a gestagen will increase the level of bad cholesterol in the body and contribute to the retention of excess fluid.

Who are contraindicated for oral contraceptives?

First of all, those women who have a tendency or poor heredity to varicose veins should refuse hormonal contraception, because all oral contraceptives, without exception, thicken the blood and contribute to the development of thromboembolism in the future. It is not recommended to take OCs for women who smoke after 35 years of age, because this further increases the risk of thrombosis. OCs should not be prescribed for severe obesity, impaired liver and kidney function, or high blood pressure, cardiac pathologies. Oral contraceptives are prescribed with caution to patients with diabetes mellitus.

My article

There are many ways to protect yourself from unwanted pregnancy. The most popular today is the use of oral contraceptives (OCs). For several decades now, women all over the world have been using this method, which significantly reduces the number of abortions and, as a consequence, complications after them.

Hormonal contraception is designed not only to protect a woman from unwanted pregnancy, but also to improve the quality of life. The fact is that now women rarely turn to a gynecologist with only one purpose - to choose a contraceptive. According to statistics, more than 60% of women have certain gynecological problems and need their correction. OCs are one of the methods for treating pathology of the pelvic organs, be it rehabilitation after abortion, treatment of PMS or endometriosis, as well as mammary glands - mastopathy.

Very often, patients complain of many side effects from taking OCs: swelling, increased blood pressure, weight gain, severe PMS symptoms, headache, stress. And the main complaints are related precisely to this. This leads to the question: how to choose hormonal contraception, is it possible to change the drug and how to avoid side effects?

It is worth noting that OK is selected by the doctor taking into account your gynecological history and concomitant pathology. You can’t choose OK for yourself based on the experience of friends or colleagues - what suited them may absolutely not suit you.

Why do side effects occur?

All side effects are caused by an increased level of estrogen in the blood, which is most often caused by an incorrectly selected drug that contains a high dose of estrogen. But there is one “but” that gynecologists often do not take into account when selecting OK. The level of estrogen in the blood can be increased without the use of OCs, and this may be associated with smoking, obesity, disease gastrointestinal tract, chronic stress, thyrotoxicosis and chronic alcohol intoxication, taking certain medications (diuretics, cardiac glycosides, narcotic analgesics, non-steroidal anti-inflammatory drugs (nurofen, ibuprofen), antibiotics, anticoagulants, hypoglycemic drugs). All of the above factors contribute to an increase in estrogen levels in the blood. Therefore, when a smoking woman experiencing chronic stress comes to the gynecologist for OK and does not talk about her lifestyle to the doctor, a situation may occur when the doctor prescribes not the lowest dosage drug, but layering on existing hyperestrogenism leads to the fact that When taking OK, all known side effects appear.

In connection with the above, attention should be paid to the woman’s behavior at the gynecologist:
When visiting a doctor, be sure to tell the doctor about your bad habits.
Tell us about your activities, focus on the stress factor of your work (whether you have frequent stress or not).
If your mother and/or grandmother had heart attacks, thrombosis, strokes or varicose veins, then you should inform your doctor about this, the prescription of the drug will depend on this.
If you are taking antibiotics, painkillers, or other medications for a long time, also tell your doctor.
Don't tell your doctor that you have varicose veins. Women often mistake visible veins on their legs for varicose veins. Remember that the diagnosis of “varicose veins” can be made either by a surgeon or a phlebologist based on certain examinations (ultrasound of veins lower limbs, blood tests, certain physiological tests). If you make such a diagnosis, then back it up with certificates from a surgeon or ask for additional examination from a gynecologist.
Do not hide from the gynecologist the number of abortions performed and how long ago the last operation was performed - this information is no less important when choosing an OC.
Inform your doctor about the degree of PMS, the length of the cycle, the duration, pain of menstruation and the volume of discharge.
It is important for your doctor to know when you are planning a pregnancy. The regimen for prescribing OK - prolonged or regular - depends on this.

It is important to note that normalizing your lifestyle, giving up stress and bad habits helps reduce the level of estrogen in the blood. But it is unlikely that there will be women who will change their lifestyle specifically for OK. Moreover, all OCs were created with the goal of improving a woman’s life, which is why there are dozens of different drugs on the market. And not a single pharmaceutical company will miss its economic benefits and will not force a woman to change her usual lifestyle. Rather, pharmaceutical companies will release a dozen more OCs in order to satisfy the need for contraception and improve the quality of life of every woman.

If the drug is not suitable for you.

First, let’s figure out what “not suitable” means. Each OC has a certain period during which it must be “integrated” into the woman’s body. This means that the drug, firstly, is a good contraceptive, secondly, it relieves a woman of concomitant pathologies (endometriosis, PMS, etc.) and, thirdly, it no longer produces side effects. This should take from three (on average) to six months. In these three months you should have completed everything side effects from OK and you just shouldn’t notice the drug. If nothing has changed during these three months, and side effects remain, then there are 2 ways to solve the problem: 1. start leading a healthy and calm lifestyle and 2. replace OK. In the first case, normalizing your lifestyle will reduce the level of estrogen in the blood, thereby mitigating side effects. And in the second case, the drug is replaced with one where the dose of estrogen is lower.

The replacement occurs as follows: you finish a pack of OK, take a week break and start drinking new drug. Of course, before this you should visit a gynecologist.

But even here, not everything is so simple. There are OCs that are very similar in estrogen content: 20 and 30 mcg. The gynecologist will choose a lower dosage if you are at high risk of thrombotic complications, if your close blood relatives have had heart attacks, strokes or thrombosis. Therefore, it is imperative to explain everything in detail to the doctor, especially with regard to medical aspects.

You should not immediately buy a large package of OK, where the tablets last for three months, since the drug may not be suitable.

The doctor's view on the prescription is OK.

When selecting an OC, the gynecologist takes into account the presence of general and gynecological pathology in a woman. A general blood test is done and, if necessary, hormone tests. But it is very difficult to study the level of estrogen in the blood - the production of this hormone does not occur linearly, and one analysis is not enough. Therefore, the doctor most often limits himself to standard examinations, such as examination, ultrasound of the pelvic organs, general tests blood and urine, questioning the patient (history taking). Additionally, the gynecologist may prescribe a study hormonal levels, including hormones thyroid gland, study of veins, gastrointestinal tract and so on. Your task is to state your complaints as clearly as possible, focusing on the main thing.

Currently, OKs are divided into several types:

According to hormone dosage:
1. Monophasic, containing the same dose of estrogen and gestagen
2. multiphase (two- and three-phase). These OCs contain a variable (non-constant) dose of hormones, which is similar to the production of hormones in a woman’s natural cycle (without taking OCs). Currently, three-phase OKs are the most popular.

Important! Action of three-phase OK:
the ovaries decrease in size
temporary sterility occurs, i.e., there is no ovulation
many atretic “non-functioning” follicles
atrophic phenomena occur in the endometrium, so the fertilized egg does not attach (if ovulation does occur)
peristalsis of the fallopian tubes slows down, so if ovulation occurs, the egg does not pass through the fallopian tubes.
Cervical mucus becomes viscous, making it very difficult for sperm to penetrate the uterus

Hormone dosage:
1. high dose
2. low dosage
3. microdosed

To monophasic high-dose OCs include: Non-ovlon, Ovidon. They are used for contraception rarely, for short periods of time and only for medicinal purposes.

To monophasic microdosed OCs relate:
Logest

Lindinet (generic Logesta). Can be used by nulliparous girls from 15 years of age. They have a beneficial effect on PMS, painful menstruation, mastopathy and menstrual irregularities. They prevent fluid retention in the body and have an antiandrogenic effect.

Novinet (generic Mercilon), Mercilon. Can be used by nulliparous girls from 15 years of age. They have an antiandrogenic effect.

Miniziston 20 fem. Can be used by nulliparous girls from 15 years of age. Has a beneficial effect on painful menstruation.

To monophasic low-dose applies:
Marvelon

Regulon

- both have weak antiandrogenic properties

Microgynon, Rigevidon, Miniziston - traditional OK

Silest, Femoden, Lindinet 30 - have weak antiandrogenic properties

Janine - first choice OK with a therapeutic effect for endometriosis, acne, seborrhea

Diane-35 - used for polycystic ovary syndrome, for elevated level testosterone. Has a pronounced antiandrogenic effect, exhibits maximum therapeutic effect for seborrhea and acne

Belara - has a slight antiandrogenic effect - improves the condition of the skin and hair (reduces the secretion of the sebaceous glands) (compared to Diane-35, antiandrogenic activity is 15%),

Yarina

- prevents fluid retention in the body, helps stabilize weight, improves the condition of the skin and hair (compared to Diane-35, antiandrogenic activity is 30%), eliminates PMS.

Midiana

Three-phase OK:

Triquilar

Triziston, Tri-regol, Qlaira. Simulates the menstrual cycle. Indicated for adolescents with delayed sexual development. Often cause weight gain. The side effects of estrogen are the most pronounced.

Single-component progestin preparations:

Microlut, Exluton, Charozetta - can be used during lactation. Can be used if COCs are contraindicated. The contraceptive effect is lower than that of COCs. Amenorrhea may develop while taking medications.

Norkolut - has androgenic activity, used mainly for medicinal purposes to normalize the condition of the endometrium.

Postinor, Zhenale - emergency contraception. Often calls uterine bleeding. It is not recommended to use more than 4 times a year.

Escapelle - causes inhibition of ovulation, prevents implantation of a fertilized egg, changes the properties of the endometrium, increases the viscosity of cervical mucus. When taken, menstrual irregularities and uterine bleeding often develop.

It is clear that only for contraception it is best to use microdosed preparations, since they contain a minimal amount of estrogens. Accordingly, when taking these OCs, side effects will be minimized. Please note that in each group of drugs, for example, in monophasic low-dose drugs, many drugs are similar to each other. The question arises: what exactly is the difference? For example, Marvelon, Regulon, Microgynon, Rigevidoe have the same amount of estrogen (30 mcg) and progestogen (150 mcg). It's simple: firstly, these may be different manufacturing companies, and, secondly, there may be generics and original drugs. It is believed that original drugs are better than generics because they are better purified and have high bioavailability and better absorption. They are considered to have fewer side effects. Although, generics have existed for decades and are also produced with decent quality, like the original drugs.

At heavy and prolonged menstruation It is likely that drugs with an enhanced gestagen component are better tolerated - Microgynon, Miniziston, Femoden, Lindinet 30, Rigevidon, Diane-35, Belara, Zhanin, Yarina. For short and scanty periods - with an enhanced estrogen component (Sileste)

Women with hypersensitivity to estrogen(nausea, vomiting, abdominal pain, tension in the mammary glands, increased vaginal mucus formation, heavy menstruation, cholestasis, varicose veins) it is advisable to prescribe combined OCs with a pronounced progestin component.

Among women up to 18 years and after 40 preference should be given to drugs with minimal content of estrogens and gestagens (Logest, Lindinet 20, Miniziston 20 fem, Novinet, Mercilon)

For teenagers You should not use long-acting medications (Depo-Provera, Mirena IUD), as they contain high doses of steroid hormones (estrogens and gestagens) and are poorly tolerated.

Alternative to OK - intrauterine devices, Nuvaring ring and barrier methods

Good afternoon. Let me ask a question about contraception in my own topic, because... Here are links to medical history and other descriptions of problems that arise while taking OCs.
Today we are thinking about whether to take a break from taking OK (generally a break for a couple of months), or what to keep - Jess or Janine. The situation is like this:
Now I am 35 years old, having 1st IVF, weight 65, height 166, I have hirsutism (medium, back and stomach and cheeks are not hairy, legs - I constantly epilate, several hairs on the abdominal line, around the nipples, above the lip).
I took Janine from July 2011 to November 2012, cysts (follicular) appeared periodically, in the last 4 months of taking Janine (July 2012 November 2012) in the middle of the cycle (on the 14th tablet) a menstrual-like reaction occurred, lasted about 5 days, but I continued the pills. during the 7-day break - on days 3-4 I had very scanty periods. And so on for several months. At the same time, I began to gain a little weight (precisely during these months).
I contacted a gynecologist - they advised me to switch to Visanne (if finances allow) or Jess.
I started right after Jeanine Jess - from November 2012 to June 2013. strictly according to the instructions. The situation with the cysts is the same - that is, no, the weight has returned to normal. But again, in the middle of the cycle, discharge continued to appear (when 2-3 days later, when it was more and more abundant, I took dicinone). During the 4-day break, my period came on 1 day, sparingly. Those. For the first 2 months I was fine-tuning, the next three months everything seemed to be optimal, the next 3 months the situation was similar to the situation with Zhanin.
Again I turned to the gynecologist. The doctor said that I need to go back to Zhanine - it has an antiandrogenic therapeutic effect, but Jess only has the effect of not retaining fluid, and there is no therapeutic antiandrogenic effect for my age. If I’m going to get pregnant, then I’ll switch to Visanne (for now I simply can’t handle Visanne financially, and its anti-endometriosis effect seems to be good, but on such drugs I’ll gain weight and go into artificial menopause, what kind of pregnancy is that?).
In general, from mid-June 2013 I started taking Janine again. In total, I am now taking the 2nd pack of Janine after Jess.
The picture - on the first pack in the middle of the cycle, as usual on the 14th tablet, was covered up - lasted 2 days and everything stopped. During the 7-day break, M did not come at all. The tests are negative (and it’s unlikely because I’m an ecologist). Now on the 2nd pack of Zhanine on 14 tablets again pink discharge began, the chest was swollen, the stomach was swollen. weight gain began again.

I don’t understand, do my periods now come in the middle of taking the pills? Do they not come during breaks? Very unclear.
1. What should I do - go to Jess again (do you think it’s suitable for me, taking into account my medical history), at least I have less weight on it, my chest doesn’t hurt, I can go to the toilet better, my stomach doesn’t seem to be blowing like that, although there were also follicular cysts. if yes, then from what day? (quit Zhanine, start Jess, finish Zhanine, start Jess immediately or after 7 days, quit Zhanine now, wait for the end of the discharge, which now started on the 14th tablet, switch to Jess after that?)
2. Continue Janine? What regimen should I take in the future?
3. Should I cancel altogether? (truth, menopause is stress for the body, and presumably it will cover me, and the hair will begin to fall out on my head and grow rapidly on my body, and the weight will creep up, and again the cycle will be 20 days with periods every week and constant spotting).
4. Somehow change the dosage schedule (assuming that breakthrough bleeding is still due to menstruation not arriving on time).
I don’t know what to do, but I don’t like Zhanin yet. I don’t want to jump around other OK ones either. After all, I found out in person the opinions of several gynecologists - they were suggested - Chloe, Klaira, Jess, Zhanine, Visane. everyone insists on their own. I have only used two drugs so far, I don’t want to try anything else.
The results of the penultimate May 2013 ultrasound - a two-chamber cyst in the LA, the last ultrasound on June 24, 13 - in general everything is fine, only small cysts 1-2 mm of the endocervix (in the cervix).



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