Phlebodia - instructions for use. Phlebodia is an effective angioprotective drug based on diosmin Use during pregnancy: a controversial issue

is a product of a French company that has firmly established itself in the Russian pharmacy market. Angioprotector drug for solving problems with varicose veins.

Phlebodia 600 - a remedy for varicose veins

Release form and composition of Flebodia 600

Medication Flebodia 600 is available in pink film-coated tablets. The package contains 1-2 blisters (15 tablets each).

One unit of the product contains 600 mg of the main active ingredient (diosmin) and a number of auxiliary components:

• stearic acid;
• colloidal silicon dioxide;
• microcrystalline cellulose;
• talc.

Packaging of Phlebodia 600 tablets

The drug is dispensed in pharmacies without a prescription and remains fit for use for 3 years from the date of issue. It must be stored in a place inaccessible to children at a temperature level not exceeding 30˚ C.

Price and analogues

Phlebodia 600 is a foreign product, which affects its cost. At the same time, there are several Russian analogues this tool, which have a more reasonable price.

Name	Manufacturer country	Quantity	Price, rub.)
Flebodia 600	France	15 tablets	from 534
		30 tablets	from 875
Venozol	Russia	36 capsules	from 311
		60 capsules	from 499
Venolek	Russia	30 tablets	from 399
Venarus	Russia	30 tablets	from 547
		60 tablets	from 912
Detralex	Russia	30 tablets	from 750
		60 tablets	from 1400
	Russia	30 tablets	from 723

If necessary, Phlebodia 600 can be replaced by a cheap or equal in cost Russian drug. The most obvious competitor of this drug is the inexpensive but effective Venozol.

Indications Flebodia 600

Phlebodia is a concomitant medication and is used as one of the components of a complex therapeutic effect, allowing:

• eliminate lymphovenous insufficiency of the legs;
• restore disturbed microcirculation;
• ensure the elimination of symptoms in hemorrhoids in the acute stage.

These are the main indications for the use of the drug, but the attending physician may prescribe it for other pathological conditions.

With exacerbation of hemorrhoids, you need to drink 2-3 tablets per day

Treatment of hemorrhoids should occur using several medications. If such an effect did not bring the desired results, then it is necessary to undergo a specialized examination and adjust the therapy.

People with hypersensitivity during the therapeutic course require a break to relieve:

• heartburn;
• headache and abdominal pain;
• feelings of nausea.

With the aggravation of any of these phenomena, you should immediately visit a specialist and get qualified help from him.

Contraindications and side effects.

Among the contraindications to application of Phlebodia 600 indicates:

• excessive sensitivity to the components of the drug;
• lactation period;
• age less than 18 years;
• the first three months of pregnancy.

In the early stages of pregnancy, it is contraindicated to take Flebodia 600

In the case of the use of the drug by women during pregnancy in the second or third trimester, no side effects were noted. However, the drug can only be used as prescribed by a specialist, since for a child this action poses a certain risk.

Symptoms associated with an overdose or concomitant use of the drug with other drugs have not been identified. Also, there was no effect of the drug on the ability to drive a car or other vehicle.

What's better?

The difference between medicines similar action and its composition can be large.

To make an unmistakable choice, you have to answer a number of questions:

• what the drug contains in addition to the active substance;
• how to take the chosen medicine;
• what price will you have to pay for a medicine in a pharmacy.

Partially understand this helps to understand the instructions that are attached to all drugs, but it is better to have an accurate idea of ​​​​how a certain remedy works.

Phlebopha or Phlebodia?

The speed of action of the drug Flebof is slightly higher than that of Flebodia, since after 2 hours from the moment of administration, its concentration in the blood already becomes maximum. For the price, it also surpasses its French counterpart.

You need to take it several times a day before meals or after, while the size of the maximum daily dose cannot exceed 1800 mg.

Flebofa is more expensive than Phlebodia 600

According to the results of the research, it was revealed that, unlike Phlebodia, Phlebofa does not have a negative effect on the child that the woman is carrying, therefore this remedy can be safely taken during pregnancy.

However, during lactation, it is recommended to refrain from using Phlebof.

Detralex or Phlebodia 600?

In general, the effect obtained from taking Detralex and Phlebodia 600 is very similar, so the priority of one of these drugs is determined by the individual needs of the patient.

The cost of these drugs, when buying a package of 30 tablets, differs little, so this parameter can not be taken into account when comparing.

Troxevasin and Phlebodia?

Troxevasin (in tablet form) decomposes mainly in the liver. Then, together with bile and urine, it is excreted from the body. Phlebodia gives a similar load on the kidneys. Therefore, here it is necessary to determine which organ is healthier and able to withstand treatment with such drugs.

Troxevasin puts a strain on the liver

The presence of renal insufficiency makes it impossible to take both drugs. Also, Troxevasin is not suitable for people suffering from stomach and intestinal ulcers.

The only group of patients for whom the use of Troxevasin will definitely be preferable is allergy sufferers. In addition, they appoint him not from the age of 18, but from the age of 15.

Phlebodia 600 ( active substance- diosmin) - the original venoprotector from the French pharmaceutical company "Laboratory Innotech International". The drug has a venotonic effect (increases their tone in a dose-dependent manner, reduces extensibility, prevents venous congestion), accelerates the outflow of lymph, thereby ensuring the implementation of the drainage function (tones and increases the frequency of contraction of the muscular membrane of the lymphatic capillaries, increases their functional activity, reduces pressure in the lymphatic channel) , stimulates blood flow in the capillary bed (dose-dependently increases vascular resistance, reduces the permeability of capillary walls), prevents leukocytes from sticking to the walls of the veins and inhibits their movement into paravenous tissues, improves the diffusion of molecular oxygen and promotes oxygenation of the skin tissue. In addition to this, Phlebodia 600 exhibits an anti-inflammatory effect, enhances the vasoconstrictor effect of catecholamines, blocks the reproduction of free radicals, the synthesis of inflammatory mediators and allergic reactions prostaglandins and thromboxane. The drug is rapidly absorbed in the gastrointestinal tract and enters the systemic circulation in therapeutically significant concentrations within 2 hours after administration. The maximum concentration of the active substance in the blood plasma is observed 5 hours after ingestion. The drug is evenly distributed and accumulated in the thickness of the walls of the vena cava and superficial veins of the legs, and also, to a lesser extent - in internal organs(kidneys, liver, lungs). The accumulation of Phlebodia 600 and its metabolites in the vessels of the venous bed reaches its highest rate at 9 hours after oral administration and persists for 4 days. The main part of the drug is excreted by the kidneys, the remaining amount - through the intestines.

Phlebodia 600 is available in the form of tablets. Before starting a medication course, you should consult with a specialist. With varicose veins with localization pathological process in the veins lower extremities, as well as with swelling, pain and convulsions, which are the result of chronic lymphovenous insufficiency, the drug is taken on an empty stomach, 1 tablet per day.

The duration of treatment is usually 2 months. In acute hemorrhoids (or exacerbation of chronic) Phlebodia 600 take 2-3 tablets per day with meals for 1 week. If, for some reason, the drug is missed, the missed doses should not be compensated for by taking additional doses (pharmacotherapy continues as usual at the same doses). Treatment of acute hemorrhoids should be complex (in other words, not based on one drug). If the clinical effect is not sufficiently pronounced, the patient should be referred for additional examination and adjustments to the treatment should be made.

The effectiveness of Phlebodia 600 has been demonstrated in a number of clinical studies, the largest of which involved about 7,000 patients. As part of this study participants took 1 tablet of the drug per day (in acute cases - 2 tablets). Patients were subjected to a medical examination before and at the end of the first month of treatment. In general, the observation lasted for 2 months. Study participants were instructed to forego other phlebotonics and to avoid significant adjustments to their lifestyle and routine habits (including food preferences and physical activity levels). The results obtained at the end of the clinical trial made it possible to state the high therapeutic efficacy of Phlebodia 600 and to determine the optimal ways of using the drug. The drug showed itself from the best side, surpassing its competitors in the pharmacological "niche". So, when using Phlebodia 600, more than 80% of positive outcomes were obtained, while for other venotonics this indicator did not exceed 40%. The dependence of the effectiveness of therapy on its duration was noted. So, the good results obtained by the end of the first month of the drug course, provided that the drug is continued, are transformed into excellent ones.

Pharmacology

The drug has a phlebotonizing effect (reduces vein extensibility, increases vein tone (dose-dependent effect), reduces venous congestion), improves lymphatic drainage (increases the tone and frequency of contraction of lymphatic capillaries, increases their functional density, reduces lymphatic pressure), improves microcirculation (increases the resistance of capillaries (dose-dependent effect), reduces their permeability), reduces the adhesion of leukocytes to venous wall and their migration to paravenous tissues, improves oxygen diffusion and perfusion in the skin tissue, and has an anti-inflammatory effect. Enhances the vasoconstrictive action of adrenaline, norepinephrine, blocks the production of free radicals, the synthesis of prostaglandins and thromboxane.

Pharmacokinetics

Rapidly absorbed from the gastrointestinal tract, found in plasma 2 hours after ingestion. C max in blood plasma is achieved 5 hours after ingestion. It is evenly distributed and accumulated in all layers of the wall of the vena cava and saphenous veins of the lower extremities, to a lesser extent - in the kidneys, liver and lungs and other tissues.

The selective accumulation of diosmin and / or its metabolites in the venous vessels reaches a maximum by 9 hours after ingestion and persists for 96 hours. Excreted by the kidneys - 79%, intestines - 11%, with bile - 2.4%.

Release form

Pink, film-coated tablets, round, biconvex.

	1 tab.
diosmin in terms of dry matter	600 mg

Excipients: talc - 10.24 mg, colloidal silicon dioxide - 3.5 mg, stearic acid - 50.05 mg, microcrystalline cellulose - up to 910 mg.

The composition of the film shell: Sepifilm ® 002 (hypromellose (E 464) - 9.832 mg, microcrystalline cellulose - 7.866 mg, macrogol 8 stearate type 1 - 1.967 mg); Sepispers ® AP 5523 pink (propylene glycol - traces, hypromellose (E 464) - 0.458 mg, titanium dioxide (E 171) - 4.026 mg, crimson dye [Ponso 4R] (E 124) - 0.401 mg, iron oxide black (E 172) - 0.13 mg, iron oxide red (E 172) - 0.02 mg); Opagloss ® 6000 (Carnauba wax (E 903) - 0.075 mg, beeswax (E 901) - 0.075 mg, shellac (E 904) - 0.15 mg, ethanol 95 ° - traces).

15 pcs. - Al/PVC blisters (1) - cardboard packs.
15 pcs. - Al/PVC blisters (2) - cardboard packs.

Dosage

Before using the drug, you should consult your doctor. The drug is intended for oral administration.

With varicose veins of the lower extremities and chronic lymphovenous insufficiency (edema, pain, convulsions), 1 tab. / day is prescribed. on an empty stomach in the morning. The duration of therapy is usually 2 months.

With exacerbation of hemorrhoids, the drug is prescribed 2-3 tablets / day. during meals for 7 days.

If one or more doses of the drug are missed, it is necessary to continue using the drug as usual and at the usual dose.

Overdose

Overdose symptoms are not described.

Interaction

Clinically significant interaction effects with other drugs have not been described.

Side effects

In rare cases, hypersensitivity to the components of the drug, requiring a break in treatment: on the part of the gastrointestinal tract - dyspeptic disorders (heartburn, nausea, abdominal pain), on the part of the central nervous system - headache.

If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects not listed in the instructions, tell your doctor.

Application features

Use during pregnancy and lactation

So far, in clinical practice, there have been no reports of any side effects when using the drug in pregnant women. Application during pregnancy in the II and III trimesters is possible only on prescription in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

In experimental studies, no teratogenic effects on the fetus have been identified. During breastfeeding it is not recommended to take the drug, because. there is no data on the penetration of the drug into breast milk.

Use in children

Contraindicated in children under 18 years of age.

special instructions

Treatment of an acute attack of hemorrhoids is carried out in combination with other drugs, in the absence of a rapid clinical effect, it is necessary to conduct an additional examination and adjust the ongoing therapy.

Influence on the ability to drive vehicles and control mechanisms

There is no evidence of a negative effect of the drug on the ability to drive vehicles and other mechanisms.

The description is up to date 04.02.2017

• Latin name: Flebodia 600
• ATX code: C05CA03
• Active substance: Diosmin (Diosmin)
• Manufacturer: Innothera Chouzy (France)

Compound

Granulated diosmin (the main active substance of the drug), which corresponds to purified anhydrous - 600 mg.

Auxiliary components:

• talc;
• colloidal silica ;
• stearic acid;
• microcrystalline cellulose ;
• a mixture of dyes - red cochineal (Ponceau 4R), titanium dioxide, propylene glycol , red and black iron oxide;
• opagloss 6000 - palm and beeswax, gummilk, 95% ethanol.

The protective cover film consists of:

• hypromellose ;
• microcrystalline cellulose;
• polyethylene glycol stearate 400.

Release form

Biconvex tablets, round, pink coated (protective film type sepifilm 002). On section, they look like a gray-brown core with a surrounding light mantle. Packed in 15 pieces in a blister, a cardboard box, one or two blisters.

Pharmacological action

Main Effects medicinal product directed to the venous bed:

• reduces the extensibility of veins;
• tones the vascular wall;
• strengthens the wall of capillaries, to a large extent preventing the possibility of their damage;
• eliminates to a certain extent venous congestion ;
• raises resistance of the microvasculature ;
• reduces the permeability of venous capillaries.

Phlebotonizing effect the active ingredient is dose dependent , that is, the manifestations of biological action are directly proportional to the amount of the drug taken.

Phlebodia also affects lymphatic vessels - significantly increases the frequency of capillary contractions, thereby increasing their functional capacity (increases lymphatic drainage ), reduces lymphatic pressure, expands the density of the vascular bed.

The drug improves the blood supply to the skin, as it facilitates oxygen diffusion and perfusion in the epidermal integument, and stimulates the microvasculature.

Separately, it should be noted that Phlebodia affects the active components of a biological nature:

• enhances vasoconstrictive effects , norepinephrine ;
• prevents the release free radical elements , prostaglandins And thromboxanes ;
• reduces adhesion to the walls of the venous bed;
• reduces the number of free superoxide anion ;
• reduces redistributive migration of white blood cells into paravenous tissues.

Pharmacodynamics and pharmacokinetics

Phlebodia tablets are rapidly adsorbed from gastrointestinal tract(taken orally). It is found in plasma after two hours, and the maximum concentration of the drug in the blood is observed five hours after the use of the drug.

Diosmin evenly deposited, both in the vena cava and in the foot vascular bed of the lower extremities or in other tissues. Active components are excreted mainly through the kidneys (about 80 percent of a single dose), to a lesser extent with feces (about 11 percent) and bile (2.4 percent).

Indications for use

• feeling heaviness in the legs , especially in the evening;
• initial stages of development or hemorrhoidal crisis ;
• prevention and treatment insufficiency of the lymphatic ;
• burning in the lower extremities in a horizontal position;
• microcirculation disorders;
• increased capillary fragility .

Contraindications

• intolerance, hereditary idiosyncrasy or individual hypersensitivity to the constituent components of the drug;
• period lactation and breastfeeding for young mothers;
• age group under 18 years old.

Side effects

The drug Phlebodia is usually well tolerated, providing the maximum therapeutic effect without side effects. However, in the clinical practice of some qualified specialists, adverse reactions such as:

• (vomiting, nausea, upper abdominal pain, bad smell from mouth);
• headache or ;
• (rashes, , and so on).

Such side effects do not require treatment and disappear on their own after a short break in conservative therapy.

Instructions for use Flebodia 600 (Method and dosage)

Tablets are used orally , regardless of food intake, physical activity and periods of wakefulness. The treatment regimen is prescribed individually by the attending physician or a qualified pharmacist, but usually follows one of the three most tried and tested methods.

If the medicine is used in the treatment varicose veins or chronic insufficiency venous bed lower extremities, the daily dosage of the drug is 1 tablet per day. The course depends on the pathophysiological stage of the disease: the initial stages of development require taking the drug for two months, and later - three to four months. In the presence of trophic changes in the skin ( necrotic ulcers as an extreme degree of development of pathology) the course is extended to six months. Repeat, treatment can every two to three months.

Instructions for Phlebodia 600 with exacerbation of hemorrhoidal inflammation venous caverns of the rectum is much easier to remember. 2-3 tablets are prescribed per day for a week to relieve an acute condition. Further, if necessary, the course is extended with one tablet per day for two to three months.

During the second and third trimester of pregnancy, the drug helps to get rid of chronic lymphovenous insufficiency if taken 1 tablet once a day. It is recommended to take a therapeutic course under the supervision of qualified specialists, that is, with inpatient treatment . Sanitation should be stopped two to three weeks before delivery, which should be reported by the attending physician.

Overdose

Symptoms of increased concentration of the drug in blood plasma are not registered.

Interaction

No significant effects have been described with the combined use of drugs with Phlebodia tablets.

Terms of sale

The drug is on free sale, that is, it is sold in pharmacy kiosks without presenting a prescription form.

Storage conditions

Tablets should be stored in a dry place out of the reach of younger children. age category, at room temperature up to 27 degrees Celsius. Do not leave the drug in direct or reflected sunlight.

Best before date

special instructions

During therapy acute hemorrhoidal crisis should be observed by a proctologist and carried out regularly additional research, since the drug may not have its pharmaceutical effect immediately, which is fraught with deterioration and progression of the pathological process up to the prolapse of inflamed venous caverns from the rectum. In the absence of a quick effect, therapy is supplemented with specialized drugs. hemodynamic And tonic action .

Synonyms

, Diosmin .

Flebodia 600 analogues

Angio protectors is a big group pharmacological preparations, the action of which is aimed at strengthening the walls of the macro- and microcirculatory bed, preventing venous stasis and vascular insufficiency , pathophysiological effect on the lymphatic vessels and biologically active substances regulating these indicators.

So, in addition to Phlebodia tablets, such medicines as , Diovenor . The range of their application is in many ways similar to Phlebodia, but the price of analogues can vary greatly. For example, Vasoket costs almost twice as much in the territory Russian Federation, which is explained by the pharmacokinetic features of the drug.

Separately, it should be noted such a drug as from the group of venotonic drugs based on diosmin . On pharmaceutical forums, users often argue which is better, Detralex or Phlebodia 600, because the indications for use, the pharmaceutical effect and the therapeutic course of administration are practically the same. The secret lies in the unique technology of production processing of the main active substance in Detralex tablets. Micronization provides a more complete and rapid absorption of the drug from the gastrointestinal tract, thus, the maximum plasma concentration is observed already three to four hours after oral administration. Detralex also passes more than long period of biotransformation with the formation of phenolic acids, due to which its half-life is a little more than eleven hours.

Phlebodia during pregnancy

The drug has been included in clinical trials for teratogenicity where showed negative result, that is, no harmful effect on the developing fetus and the organism of the expectant mother was revealed. However, in order to avoid undesirable manifestations or accidental involution, the course of treatment is prescribed only after twelfth week when the initial sprouts of vital tissues and organs have already been laid.

Reviews of Phlebodia 600 during pregnancy from patients confirm the positive therapeutic effect of conservative treatment. Unpleasant sensations associated with congestion in the venous bed are significantly reduced, which contributes to an easier course of pregnancy. Also satisfied mothers are noted improved skin circulation , the integument looks more healthy and natural after the treatment.

Reviews about Flebodia 600

Reviews of Phlebodia with confirm the excellent pharmacological effect of the drug. The pathophysiological effect of the drug allows in a relatively short time to conservatively treat inflammation of hemorrhoidal cavities, even in the most advanced stages. Also, tablets can mitigate the impact of acute crises, which has a positive effect on general condition organism.

Expectant mothers undergoing therapy lymphovenous insufficiency chronic type during pregnancy, are also completely satisfied with the drug. Phlebodia allows you to get rid of the unpleasant sensations that inevitably accompany venous congestion, which greatly facilitates the course of the physiological bearing of a child. Separately, it should be noted that due to a more active blood supply to the skin and a venotonic effect, Phlebodia has a cosmetic effect on a woman's body.

Reviews of doctors who use the drug Flebodia in their clinical practice characterize the drug on the good side, because the pharmaceutical effect provided occurs relatively quickly. Among similar angioprotectors, tablets take the second place in this parameter. Also, the rare development of adverse or undesirable reactions, which, moreover, pass without special medical intervention, gives a hundred points of form before any other venotonic agent of general therapeutic action.

Price Phlebodia 600, where to buy

The price of Flebodia 600 on the territory of the Russian Federation is 400-700 rubles for a small package (one contour blister - 15 tablets). A drug designed for a longer therapeutic course ( 30 tablets in double cell packaging) can be purchased for 800-870 rubles.

In Ukraine, such pills for hemorrhoids can be bought a little more expensive. So, for example, a large set Phlebodia (30 tablets) it costs almost 300 hryvnia, and a small one costs 160-190 hryvnia.

• Internet pharmacies in Russia Russia
• Internet pharmacies in Ukraine Ukraine
• Internet pharmacies of Kazakhstan Kazakhstan

ZdravCity

Phlebodia 600 tab. p.o n15

Phlebodia 600 tab. p.o n60 Innotera Shuzi

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Phlebodia 600 tab. p / o captivity. 600mg #18 Innotera Shuzi

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Phlebodia 600 mg n15 tablInnotera Shuzi-Laboratory Innote

Phlebodia 600 mg No. 60 tab. Innotera Shuzi

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Note!

Information about medicines on the site is a general reference, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medicines in the course of treatment. Before medicine use Phlebodia 600 surely consult with the attending physician.

Reviews

Phlebodia was discharged by a vascular surgeon when he diagnosed varicose veins. I accept in combination with the use of compression stockings. I have now started my second month. I can say that the effect is there and well noticeable. Puffiness subsided from the legs, the veins no longer ache like that. Satisfied with the effect, I will continue to take it further.

The best venotonic I have tried. No side effects - no headaches, no stomach problems. And I was already beginning to think that for drugs of this kind this is the norm! And here - no problems, only the desired effect: pain in the veins and a feeling of heaviness in the legs go away. After the Phlebodia course, I can even afford to dance in the evening, but before that I only thought about how to take off my shoes faster.

Both my mother and grandmother suffered from varicose veins in my family. And this problem has not bypassed me. True, knowing what kind of misfortune it was, I did not wait for the veins to go in tubercles in my legs and immediately went to the doctor. It was he who appointed me Phlebodia 600. The price at the pharmacy pleasantly surprised me (it's just that my mother drinks Detralex and it is much more expensive). The course of administration is convenient - one tablet per day is enough. It should be taken in the morning, on an empty stomach. One pack is just enough for a two-month course. In terms of effect, everything is excellent. Varicose veins, of course, are not treated, but the veins stopped hurting, the feeling of heaviness in the legs disappeared.

Flebodia helped me. I am already drinking the third course, in the first course the pain and itching in the veins stopped. I like that you only need to take one tablet in the morning - it’s convenient for me, I drank and forgot. After the course, the disease did not make itself known until the start of the next course. So, if you drink regularly, then you simply forget about varicose veins.

Tablets are good. My husband is a phlebologist, so he knows a lot about venotonics. He says about Phlebodia that the dosage is optimal for the early stages of varicose veins, and the production is reliable, because. European. Therefore, with my hereditary varicose veins, of course, I accept Phlebodia. It is convenient to drink - one tablet on an empty stomach, it is difficult to forget about taking it. The tablet is small and easy to swallow. I personally didn't have any side effects. You begin to notice the effectiveness in the second week of taking it - there is lightness in the legs, swelling and pain in the veins gradually go away. By the end of the course, you generally forget that you have varicose veins. But it is important to drink regularly, twice a year. Then the symptoms will not return.

Varicose veins combined with standing work is a quiet horror. By the evening you simply don’t feel your legs, not to mention how much the shoes begin to press on swollen legs. But I have recently found a salvation from this misfortune - Phlebodia. I didn’t even hope that a venotonic could give such an effect! No swelling, no pain, no itching in the veins. Just a miracle! Now I drink myself and advise "comrades in misfortune".

For me, varicose veins have become a nightmare because of the terribly annoying itching in the veins. It's just unbearable! So when, on the third week of taking Phlebodia, relief came and this terrible feeling went away - I was ready to literally cry with joy! Now every year I have two courses of Phlebodia as mandatory items - I really don’t want this debilitating symptom to return!

My mother is a phlebologist and she speaks extremely positively about this drug. So when I myself had problems with blood vessels, she advised me Phlebodia. With my problem - varicose edema - the drug successfully coped. So from me and from mother Phlebodia a solid five!

I have been suffering from varicose veins for far from the first year, therefore I have studied venotonics far and wide. For many, the main problem is the effect on the stomach (either I have a weak one, or the compositions there are doubtful, but there is a side effect). The best impressions at the moment are from Phlebodia 600. There were no side effects from it, and the effect is good: pain in the veins, itching, swelling in the legs went away, and this is already in the first course of admission. Now I continue to drink it in preventive courses twice a year to keep the disease under control.

I drank after childbirth and breastfeeding, since the veins deteriorated during pregnancy. As a result - frequent swelling, pain in the legs (more precisely, in the veins), a periodically increasing number spider veins. The phlebologist advised to drink Phlebodia 600. The course is convenient - a tablet a day, in the morning, on an empty stomach. I like it, because in the morning I usually still remember what I need to do in a day, but then I can forget) In terms of effectiveness: after the first course, my legs stopped swelling. New vascular asterisks have not appeared for a long time either, I suspect that this is largely due to Phlebodia. The pain in the veins is gone. Now I drink regularly, with an interval of five months. Varicose veins stopped bothering me.

The doctor prescribed it when problems with swelling of the legs began due to varicose veins. I liked that you only need to take one tablet a day - I don’t like complex dosage regimens. The course of treatment is 60 tablets. For the price of phlebodia, probably somewhere in the middle among all venotonics. The same detralex will be more expensive, although I don’t understand why all of a sudden. In terms of effectiveness, it helped me a lot. The veins in my legs hurt terribly, straight to tears. After the course, for half a year I don’t remember the pain in the veins at all. So the tool works.

IN Last year the veins began to bother me a lot, they really hurt because of varicose veins. At first she drank Troxerutin, but he did not give any sense, apparently rather weak. But after the course of Phlebodia, all the discomfort in the veins went away completely and has not returned for several months after the course. So I am satisfied with the drug.

I have varicose veins after long walk legs are always swollen. Sometimes to such an extent that I can’t put on shoes - even crying. Well, a competent doctor suggested a course of phlebodia to me - by the middle of the course, my legs stopped swelling so much. From now on, I will be checking it regularly.

It was prescribed during a massage to reduce the venous outflow of blood from the head ... in other words, so that the pressure does not increase. It happened a couple of times that my head hurt, but, in general, I really liked the medicine, even my sleep improved ...

August 30, 2016, 19:48

My sister suddenly had veins on her legs, I was very worried that edema, blood clots could form, and she only cares appearance. I smeared myself with some kind of gels, covered my legs with a leaf of burdock, my legs only got worse, it was so hard to walk in the mornings. But as soon as the sister reached the doctor, phlebodia was fully treated, pain and swelling disappeared, although the appearance remained the same, but the disease does not progress and does not cause discomfort.

Phlebodia is taken only once a day, one tablet, while other venotonics are taken at least twice and quite often two tablets each. Phlebodia is definitely cheaper than many. As for the effectiveness, it is approximately the same for all drugs, because they all contain diosmin.

During pregnancy, I did not take any medication, although my legs swelled, hurt, the mesh was drawn, but I was more afraid of hurting the baby. After giving birth, everything only got worse, and I had to start drinking Phlebodia, I don’t breastfeed anyway, so nothing interferes. The effect was even surprising - the pain and swelling went away completely. The grid remains, but there's nothing to be done here.

I am a dentist and spend 6 hours a day on my feet. I noticed that half a year ago, a venous network on my legs began to appear, my legs began to get very tired and swell in the evening. I was alert, because. doctor and I know that if you do not pay attention to this, then this condition can turn into varicose veins, and then thrombophlebitis is just around the corner. I needed to find a drug that would be not only effective, but also convenient to take. We have been friends with Phlebodia 600 for 2 months. 1 tablet in the morning and flew to work. After a month of taking the heaviness in the legs went away, there was a noticeable lightness and they stopped swelling.

March 2, 2016, 17:23

It copes with the indications for use, the symptoms of the disease quickly disappeared. But there was a side effect - a headache.

show more reviews (32)

A variety of pathologies of the veins are increasingly forcing a person to resort to the help of a doctor. In the earliest stages of the disease, there is a high chance of correcting the problem with conservative methods. When pathology affects large areas, doctors insist on surgical operation or other minimally invasive intervention. However, even after this procedure, the patient is forced to take appropriate medications. One of these is Phlebodia 600. The price, reviews and analogues of the drug will be described in this article. You will also learn about the composition of the medicine. It is worth mentioning that the instructions for use inform about the tablets "Flebodia 600". Reviews of doctors about the use during pregnancy are described below.

What is included in the preparation?

About the drug "Flebodia 600" reviews are mostly positive. All because of its simple composition. The active ingredient of the drug is diosmin in the amount of 600 milligrams. However, there is no hesperidin, which is present in most of these drugs. That is why patients who have intolerance to the latter substance can take Phlebodia 600 without any fear.

Instructions, manufacturers' reviews also report that additional substances are present in the preparation. These are colloidal silicon dioxide and talc, also acid and MCC. The rest of the components do not therapeutic effect on the body, but are intended only to give the drug the appropriate form.

How does the drug work?

The medicine "Flebodia 600" has good reviews because of the quick effect. The drug begins to act within two hours. However, its maximum effect appears only after 9 hours. It is at this time that the concentration of the active substance in the blood is at highest level. Consumers also prefer this medication due to the fact that its effectiveness lasts up to 96 hours. Only on the fourth day after application, the composition is completely removed from the patient's body.

What else can the instruction tell about the drug "Flebodia 600"? Consumer reviews report that the annotation indicates pharmacological actions. So, the drug has anti-inflammatory and anti-edematous efficacy. It affects the walls of blood vessels and veins, and also affects the blood. The drug reduces the extensibility of capillaries and helps to increase their tone. It also reduces the binding of leukocytes to the walls of blood vessels. A slight thinning of the blood contributes to the normalization of its outflow from the lower extremities. In addition, the drug fills the blood vessels and veins with oxygen, which improves the patient's condition.

Information on indications for the use of the composition "Flebodia 600"

The drug should be prescribed exclusively by a doctor. Incorrect use of the composition or abuse of doses leads to the development of an unpleasant adverse reaction. You will be told about it a little later. First, it is worth mentioning the indications for the use of the drug. The annotation indicates the following situations:

• haemorrhoids different kind in the stage of exacerbation or remission;
• soreness and swelling of the lower extremities;
• and spider veins;
• violations of microcirculation of blood and lymph;
• after phlebectomy or minimally invasive interventions for the treatment of venous insufficiency.

Often about the drug "Flebodia 600" reviews report that it is used as a prophylaxis. In this case, the drug is recommended for initial stages vein disease, during pregnancy, with sedentary work and wearing uncomfortable shoes. Indications for use in each individual case may be different. That is why it is worth contacting doctors before using the composition.

Contraindications for use and restrictions

The drug is not prescribed for those patients who are hypersensitive to the components. Also, tablets are prohibited for use by persons under 18 years of age. Such use is fraught with consequences, since in adolescence the lymphatic system continues to form and grow and the Composition is not prescribed for bleeding of unclear etiology, because it can aggravate an already serious problem.

Medication "Flebodia 600" is not recommended during lactation. The active substance is able to penetrate into breast milk and affect the child. However, the consequences of this influence have not yet been studied. Also, the instructions for use do not recommend taking the drug during pregnancy. However, this view is disputed.

Use during pregnancy: a controversial issue

Often women ask if it is possible to use the drug "Flebodia 600" during pregnancy. Reviews of doctors report that the medicine can be prescribed. However, it is worth abandoning it in the first trimester. After all, it is then that the formation of all systems and organs of the unborn child takes place. The medicine does not render Despite it, many doctors are reinsured and register a medicine only in the second half of term.

About the use of the drug "Flebodia 600" during pregnancy, the reviews are only positive. Women report that they have practically no anxiety from the venous system of the lower extremities. Also, hemorrhoids, which often affects future and new mothers, did not make themselves felt. Doctors say that in order to prevent Phlebodia during pregnancy, it is rarely prescribed. Usually the drug is prescribed already in the presence of problems at present or in history.

How to use the composition

How is the drug "Flebodia 600" used? Consumer reviews and doctors' recommendations suggest that the composition is best taken in morning hours. In this case, the tablets should be written down with a small amount of pure water. The dosage of the medicinal composition is selected individually in each case. Most often, the following schemes for the use of the drug are prescribed.

• With varicose veins and its manifestations, as well as after surgical interventions the medication is prescribed 600 milligrams once a day. The term of application is up to two months.
• During hemorrhoids, the dose of the drug is 1200-1800 milligrams per day. Duration of application - up to one week.
• During pregnancy, the medication is taken one capsule per day for a month. This is followed by a short break. The pattern is then repeated.

"Flebodia 600": price, reviews, analogues

Like any other medicine, the described medicine can be replaced. Often consumers ask the question: which is better, "Detralex" or "Flebodia 600". Reviews of doctors say that both of these drugs have the same active ingredient - diosmin. However, in Detralex it is only 450 milligrams. Also in this preparation contains hesperidin in the amount of 50 mg. If the patient has an intolerance to this substance, then the Detralex medicine is not suitable for him. This is why most consumers buy original drug. One pack of 15 pieces costs about 700 rubles. If you buy a pack of 30 capsules, then it will cost you 1000 rubles. The cost of "Detralex" is somewhat different. One pack with 30 tablets will cost you 800 rubles.

Another analogue of the drug is the Russian medicine Venarus. This tool is even cheaper - 500 rubles for 30 capsules. Its composition is absolutely identical to Detralex. If we talk about substitutes with other components, but with the same effect, then Troxevasin (300 rubles), Antistax (600 rubles) and many others can be noted. According to patients, of all the compositions presented, Phlebodia is the most effective.

The effectiveness of the composition in the treatment of hemorrhoids

What is the drug "Flebodia 600" reviews for hemorrhoids? Consumers report that the composition gives a very fast effect. Convenient and its use. Since most of the compositions for the treatment of such diseases are applied topically, this creates discomfort for the patient.

Consumers say that Phlebodia helps with hemorrhoids already on the first day after application. So, the pain in the affected area goes away. The inflammatory process is also eliminated. It is worth noting that with hemorrhoids, doctors recommend re-using the drug once every six months. Such a scheme will help to avoid relapse.

Phlebodia 600 is one that has a venotonic effect: it increases the tone of the veins, reduces their extensibility and reduces venous congestion. The drug improves lymphatic drainage, that is, increases the frequency of capillary contractions and their functional density, reduces lymphatic pressure.

Phlebodia 600 is also excellent for improving microcirculation, its systematic use can lead to a decrease in vascular permeability and an increase in their resistance. Phlebodia 600 has an anti-inflammatory effect and can block the production of free radicals.

Phlebodia refers to venotonics, which include. Excipients in the composition of the drug: colloidal silicon dioxide, talc, microcrystalline cellulose, stearic acid, a protective film such as Sepifilm 002, a mixture of dyes such as Sepisperse AP 5523 (these include hypromellose, propylene glycol, titanium dioxide, cochineal red (Ponso 4R), iron oxide red, iron oxide black), Opagloss 6000.

Indications for use

The properties of the drug allow you to use it:

• for the treatment and prevention, as well as chronic lymphovenous insufficiency of the lower extremities;
• for the treatment of microcirculation disorders and edematous syndrome during pregnancy.

Mode of application

If Phlebodia 600 is used to treat lymphovenous and if there are no complications, then the drug is taken 1 tablet once a day for 2 months. This course is recommended for mild varicose veins.

With moderate severity of the disease, the drug is taken 1 tablet daily, for 3 months. With a severe degree of varicose veins, including if they are formed, the drug is taken 1 tablet every day for six months.

The drug is also used for the treatment in pregnant women, which arose against the background of lymphovenous insufficiency. According to the instructions for use, in this case, appoint 1 tablet daily. Phlebodia must be canceled 2 to 3 weeks before the birth.

Pharmacokinetics

Phlebodia is rapidly absorbed from the gastrointestinal tract. In plasma, it is detected 2 hours after direct administration. The maximum concentration is reached 5 hours after ingestion. Phlebodia is evenly distributed and accumulates in all layers of the walls of the vena cava. The smallest amount of the drug accumulates in the liver, kidneys, lungs and other tissues. The main part of the drug - 79% - is excreted in the urine, of the remaining: 11% - with feces, and with bile - 2.4%.

Contraindications and side effects

Phlebodia is not used for hypersensitivity or individual intolerance to the components. Medicine cannot be used by persons under the age of 18.

Side effects:

• headache;
• dyspepsia;
• allergic reactions associated with the presence of hypersensitivity to the components of the drug.

Phlebodia and pregnancy

It is noted that in clinical practice no side effects have been identified from the use of the drug in. Moreover, experimental studies have shown that the drug does not have a teratogenic effect on the fetus.

When breastfeeding, the drug, like a number of other venotonics, is not recommended, since it has not been studied whether it penetrates into breast milk and how it affects its composition.

Overdose of Phlebodia 600 and special instructions

Signs indicating an overdose are not described in clinical practice.

There are some special instructions. In the treatment of an acute attack of hemorrhoids, phlebodia is used in combination with other drugs. If a positive effect does not occur quickly, then an additional examination should be carried out and, based on its results, the prescribed treatment should be adjusted.

Despite the fact that the list of indications for the use of the drug was indicated above, in medical practice Phlebodia is also used for the treatment of fetoplacental insufficiency, during the period and for the prevention of bleeding resulting from the use of an intrauterine device.

Reviews about Flebodia 600

Advantages of the drug:

• no side effects with long-term use;
• the ability to use the drug as a prophylactic agent. Many women with a predisposition to varicose veins noted that after taking the drug they felt light in their legs, leg fatigue disappeared;
• the disappearance of small ones;
• reasonable price - 30 tablets cost an average of $20. Since only one tablet needs to be taken per day during treatment, a monthly course is inexpensive;
• thanks to the use of Phlebodia in the complex treatment of hemorrhoids, it was possible to avoid surgery.

Disadvantages of the drug:

• large tablet size. This disadvantage can be easily overcome by dividing the tablet into two parts;
• the presence of dyes in the preparation. It should be noted that this statement is true.

Flebodia 600 analogues

Structural analogues for the active substance	Analogues for the effect
Vasoket	Agapurin Actovegin Alprostan Aescin
Diovenor 600	Betaver Betahistine Betacentrin Betaserc Bilobil Vasonite Vasaprostan Vazoserk Vesticap
Diosmin	Ginkor fort
	Dipyridamole Dicynon
	Curantyl Xanthinol nicotinate
	A nicotinic acid
	Oksibral
	Pentoxifylline Parsedil