At what value of TSH is l thyroxine prescribed. For what reasons is increased TSH and how to return it to normal

Antipyretics for children are prescribed by a pediatrician. But there are emergency situations for fever when the child needs to be given medicine immediately. Then the parents take responsibility and use antipyretic drugs. What is allowed to give to infants? How can you bring down the temperature in older children? What medicines are the safest?

Thyroxine is an iodine-containing hormone produced by the thyroid gland under the influence of pituitary thyroid-stimulating hormone. Many diseases are known, the development of which leads to disruption of the normal functioning of the thyroid gland and, as a result, a decrease in the level of thyroid hormones circulating in the blood. Trying to balance the created imbalance, the pituitary gland "spurs" the thyroid gland with an increase in thyrotropin (TSH), but the latter is far from always able to work productively. This is where the endocrinologist comes to the aid of the body with a “magic” tablet of L-thyroxine. Everything is like in a fairy tale: the symptoms slowly but surely disappear, and the doctor acquires in the eyes of the patient an aura of holiness and genius. Think this is a happy ending? Often this is almost true, but sometimes, during a follow-up examination some time after the start of treatment, the patient receives a blood test result in which the TSH is still elevated. Why this happens, who is to blame and what to do in such a situation, we will discuss below.

For reference:

  • The thyroid gland produces hormones that control almost all types of metabolism in the body.
  • L-thyroxine - obtained synthetically, an absolute analogue natural hormone tetraiodothyronine (aka T4 or thyroxine).
  • The half-life of T4 is almost two weeks, the same figure for TSH is 2 months.
  • Women suffer from diseases thyroid gland several times more common than the male half of the population.

Where does treatment begin?

Therapy with L-thyroxine is designed to compensate for the deficiency of thyroid hormones in the human body from the outside. However, all people are different, and this statement is the best fit for substitution hormone therapy. To choose the right dosage for a particular patient, the endocrinologist evaluates many different indicators: test results, height, weight, age, gender, and so on. However, even with the current development of medicine, the dosage of this remedy requires a long selection and refinement, and sometimes this process is delayed for several months.

Due to the fact that thyrotropin reacts slowly to the intake of hormones from the outside, the doctor, after prescribing replacement therapy appoints the next appointment to the patient in 2-3 months. By this time, the clinical picture will be clear enough to understand whether this dose is suitable for a person or whether there is a need to increase or decrease it. One of the criteria for evaluating the effectiveness of treatment is TSH level, which was initially increased, and after the therapy should decrease.

Return visit to an endocrinologist

Before re-admission to the endocrinologist, it is necessary to re-donate blood for thyroid hormones and thyroid-stimulating hormone (if it is elevated, the doctor will understand, but more on that below), also depending on which thyroid disease led you to the doctor, other indicators may be prescribed blood (thyroglobulin, antibodies to thyroperoxidase, etc.).

If the TSH results are higher than normal, then do not panic ahead of time. You just need to see your doctor, who will figure out what is the cause of the problem.

Why TTG has not decreased?

The reasons why TSH is elevated and does not decrease while taking L-thyroxine can be divided into two groups:

  1. The fault of the patient.
  2. Due to medication.

Separately, I single out the process of dose selection, during which TSH is higher than normal in several cases:

  1. Too low dosage of levothyroxine was prescribed.
  2. The body's need for thyroid hormones has increased due to the progression of the underlying thyroid disease.

We drink medicine correctly!

Often, as I already mentioned, TSH is elevated, despite the ongoing treatment, through the fault of the patient himself. Levothyroxine like any other medicinal substance, has its own characteristics of application. Ignoring the instructions for use leads to the fact that it does not exert its full effect. Let's discuss the most common patient errors that reduce the effectiveness of treatment.

  1. Preparations containing thyroxine taken in the morning and in one dose! Not at lunch, and even more so not before bedtime, they can not be taken. Replacement therapy should imitate the biological rhythms of the release of the hormone in the human body, and normally the largest amount of it enters the bloodstream in the morning.
  2. Levothyroxine should not be taken with or after food. Only 30 minutes before the planned meal! It cannot be well absorbed in the intestines if the gastrointestinal tract is busy digesting the freshly eaten chop at this time. Almost half of the intake will not be absorbed, which means that the actual amount of medication that your body will receive will be half that expected by the endocrinologist.
  3. Tablets should be taken daily. Any omission reduces the level of hormones in the blood, which, as a result, does not allow the doctor to adequately assess the quality of the selected dosage even after 3 months, since the already mentioned TSH rises rapidly, but is slowly excreted. As a result, TSH will be elevated in the tests, and it will take you and your doctor even longer to select the correct dose that is right for you.
  4. Hormone replacement therapy for thyroid diseases is NOT carried out in courses. Those. it is not enough to drink the medicine for a week or a month, must be taken constantly.. After all, when the thyroid gland is working properly, it produces hormones daily, so if it is not functioning, then you yourself do its work by taking your morning pill.

For reference:

  • Receiving or changing the dose of levothyroxine can only be done by an endocrinologist. It is absolutely unacceptable to independently change the amount of the drug.
  • Elevated TSH in women taking this medicine may be detected during pregnancy.

When is the drug to blame?

I’ll clarify right away: the essence of the problem is not in the medicine itself, but in its manufacturer. Unfortunately, fakes are not uncommon in our pharmaceutical market. That's what they're talking about. Counterfeit medicines are mostly just dummies, so they will not bring the desired effect. TSH has been elevated, and remains, even if you drink the drug as described earlier. This unpleasant situation has only one way to solve it: buying a new package of the drug. It is better if you purchase an analogue of the drug you are taking at another pharmacy. There are several identical versions of levothyroxine produced by different pharmaceutical companies: Euthyrox, Bagothyrox, L-thyroxine, Levothyroxine sodium, Eferox.

How to understand that the dose was chosen correctly?

First, in terms of self-perception. Secondly, your endocrinologist will see characteristic changes in laboratory tests. If at the beginning TSH was increased, and T4 was reduced, now both of these indicators should be within the normal range, with slight allowable fluctuations. Nevertheless, even a correctly selected dose does not cancel planned trips to the endocrinologist, at least once every six months.

A qualified endocrinologist with over 10 years of experience continues to answer your questions. Ask your questions in the comments if you want to get a free answer from an endocrinologist.

Question 1 (Alyonushka)

Hello, I have been diagnosed with hypothyroidism. my analyses:
TSH-5.22 miUL
T4 GENERAL-61.46nmolL
T4 FREE-11.28 pmolL
Antibodies to TPO-0.38 uml
ANTIBODIES TO TG-4.99 uml
Also elevated prolactin-48.5

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST

Hello, you have subclinical hypothyroidism, which is manifested only by an increase in TSH. You should take L-thyroxine to correct this condition. If on the background of 25 mg of the drug TSH does not decrease, then the dose should be increased. But do it only after consultation of the internal endocrinologist. Children with abnormalities are born only in the presence of untreated hypothyroidism in a pregnant woman. If you achieve a decrease in TSH and become pregnant against this background, then the child will be born healthy. Of course, provided that you take L-thyroxine throughout your pregnancy and regularly donate blood for TSH and Free T4. Regarding the use of iodine preparations, I agree with your doctor, as it can increase the existing hypothyroidism. There are many reasons for not getting pregnant, so check with your family planning office about this. Especially if it is not possible to conceive a child within a year.

Question 2 (Olga Grigorievna)

Hello, in 2011 I was diagnosed with autoimmune hypothyroidism. ttg in 2011 was 10.35 µm ml, in 2012 4.97, in 2014 4.81. I didn’t take anything for the thyroid gland. signs of hypothyroidism were observed: a slight change in weight from 60 to 70 kg with a height of 1 m 56 cm in 10 years, hair loss and deterioration in their structure, dry skin appeared. This year, the endocrinologist prescribed me iodomarin 200 mg and metformin. Ultrasound of the thyroid gland shows a hypoechoic formation 6*6*9mm. Do I need to drink thyroid hormone Iodomarin?

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST

Hello, the normalization of the TSH level sometimes happens on its own, since AIT is also a disease that can pass. At present the endocrinologist has written out to you not hormones. Iodomarin is an iodine preparation (you get the same iodine with food, but usually it is not enough in food). It should be taken regularly, as this will prevent further problems. Metformin is prescribed for the correction of carbohydrate metabolism, and has nothing to do with the work of the thyroid gland.

Question 3 (Shugla Pavlycheva)

Hello! I am 44 years old, height - 159 cm, weight - 57 kg, gender - female. The results of the blood test: TSH - 0.190 μIU / ml, T3fl - 3.4 pg / ml, T4fl - ng / dl, ultrasound - right lobe size: 3.21 - 2.44-5.34cm, V-21.86ml. nodular formations from 0.3 cm to 1 cm, echostructure - heterogeneous, echogenicity - increased. Left lobe size: 2.98-2.28-5.3 cm, V - 18.96 ml, echostructure - heterogeneous, echogenicity - increased. hypoechoic formations up to 0.2 cm. The isthmus is 0.74 cm, blood flow is increased in the CDC. Please advise what can be said from these results
ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, according to the results of the tests, it is clear that your TSH hormone is lowered. T3 is free within the normal range, but you did not indicate free T4, apparently by chance. You also have an enlarged thyroid gland. Most likely, the diagnosis sounds like this: autoimmune thyroiditis with nodulation, hypothyroidism. To confirm the diagnosis, you should conduct an additional examination: donate blood for antibodies to TPO and puncture those nodes that are equal to or larger than 10 mm. With the results, be sure to contact an internal endocrinologist, as you need to start hormone replacement therapy (Eutirox, L-thyroxine, etc.). The doctor will prescribe the dose after examination.
Question 4 (Nailya Minnigulova)

I am 55 years old, height 142 cm, weight was 54 kg, one hundred 40 kg. What does the appearance of calcification in the nodes of the thyroid gland mean?

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST

Hello, calcifications in the nodes appear due to the deposition of calcium salts. This is typical for nodes that exist for a long time. Calcifications themselves do not affect the level of thyroid hormones and cannot be the cause of weight loss. You should take a blood test for TSH, T4 free and for antibodies to TPO. If there are nodes larger than 10 mm, then it is necessary to puncture these nodes under ultrasound control.
Question 5 (Natalia Pchelintseva)

Dear doctor! Yesterday we did an ultrasound of the thyroid gland, my son is 6 years 8 months old. weight - 30 kg, gland volume - 5 cm cube (but normally it should be 4.7 cm cube, as the doctor said), diffuse changes thyroid gland. lobe volume: right - 3.7 hypoechoic foci throughout the gland, left lobe - 1.3, vascular pattern of the gland: moderately hypervascular. We will enter a cadet school, I would like to know with such an ultrasound, is it possible physical exercise?? And what examinations still need to pass?

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST

Hello, a slight enlargement of the thyroid gland may be due to a lack of iodine in the diet. To clarify the state of health of the child, take a blood test for hormones TSH and free T4. Without these analyzes it is difficult to give an answer to your question. Only the conclusion of the ultrasound can not be a cause for concern. It is necessary to evaluate the child and the results of the survey as a whole. Visit a full-time endocrinologist when you get your hormone test results. Start taking Iodomarin, after three months, redo the ultrasound.

Question 6 (Elena Ustyuzhanina)
Hello! I am Elena - 50 years old, height 148, weight 45. Since the 8th grade, the diagnosis is hypothyroidism, respectively, I have been drinking hormones all my life. Until recently, everything was fine. Now I am tormented by such misfortunes as lack of appetite with nausea, dizziness. weakness, apathy, anxious sleep, pressure in the heart area, a heavy head and thoughts, respectively, heavy and depressive. I don’t know the norm. But getting an appointment with an endocrinologist is a whole problem in our country. Although I understand that I still need to get in. Please advise, because the treatment for vegeto does not help the vessel of dystonia. Perhaps this thyroid gland torments me so much?

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, the symptoms are similar to hypothyroidism, but it is impossible to say for sure without the results of the examination. Hormone levels vary from center to center, so they should indicate their lab's normal values ​​in parentheses. The concept of vegetative-vascular dystonia is very vague. With such a diagnosis, it is necessary to treat the nervous system, take sedatives, recommended vacation, normal sleep pattern. For high blood sugar, take a glucose tolerance test. It should be done free of charge at the clinic at the place of residence. With the results of this analysis and tests for hormones, be sure to visit an endocrinologist.

Question 7 (Galina Neuvarueva)
I have had AIT for 10 years I am 63 years old weight 73 kg height 62 cm took l-thyroxine 75 mg feel age-appropriate increase in blood pressure with weather changes due to meteosensitivity pulse tendency to bradycardia but constipation from birth sometimes swelling in the legs stopped drinking the hormone TSH -75 what to do? hormone of course I will continue!
ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, you should definitely resume taking L-thyroxine at the same dosage. As soon as possible visit the endocrinologist as such status should be kept under the control by the internal doctor. A month after the start of taking the drug, take a blood test for TSH again. Also do an ultrasound of the thyroid gland. Regarding the increase in blood pressure - you need to start taking antihypertensive drugs daily. Usually treatment begins with one drug and a small dosage. The selection of the drug is carried out by the therapist or cardiologist in the clinic. This will prevent an increase in pressure, which means it will save you from serious complications - a stroke or myocardial infarction.

Question 8
Hello. My daughter is 13 years old, height 143 cm, weight 34 kg. The results of her blood test: free T4 - 1.15 ng / dl., TSH - 2.670 μIU / ml, AT-TPO - 25.33 IU / ml. According to ultrasound: the location is typical; the capsule is preserved, uniform thin; the contours are clear, uneven, bumpy, polycyclic; dimensions Dex-15.19*16.80*47.74 mm., Sin-13.53*16.88*47.19 mm., V isthmus - 0.54 cm3 Volume: Dex-5.79 cm3, Sin-5.11 cm3, Volume 11.44 cm3, (N-3.22-11.13 cm3). The structure is heterogeneous, striatal structures are hypertogenic on the left and right. Echogenicity is uneven, areas of low echogenicity alternate with areas of higher echogenicity. Elasticity is preserved, the overall echogenicity is higher than the echogenicity of the sign glands. Vascular pattern of the parenchyma SH.Zh. in color-coded modes: symmetrical on the right and left, modified: significant gain up to 1-2 tbsp. DIC: 20-40 and more than 40%. Topographic and anatomical ratios Shch.Zh. with muscles and organs are not changed. Ouse-signs: Differentiate the autoimmune process in SH.Zh. (hypertrophic thyroiditis) with diffuse non-nodular goiter. Please advise what can be said from these results. Thank you.

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, your daughter has diffuse non-toxic goiter. If you live in an area with a low iodine content in the environment, then such a goiter is called endemic. Based on the results of the tests, the hormonal background of the girl is in order. Once every 6 months I recommend doing a blood test for TSH. If this hormone is increased or decreased, then immediately repeat the blood for T4 free and for antibodies to TPO. Pay attention to your daughter's nutrition, as goiter often occurs when there is a lack of protein and vitamins in food. You should also take iodomarin at a dose of 200 mcg daily for 6 months. Get registered with a full-time endocrinologist, as the child needs constant monitoring of his health.

QUESTION 9
Olesya Ivanova
hello, I am 20 years old, height 158 ​​weight 63 My results: Research Result Reference values ​​Comment T4 free 11.7 pmol / l 9.0 - 22.0 pmol / lTSH 1.83 mU / l 0.4 - 4.0 mU / lAT-TPO< 3.0 Ед/мл< 5.6 ,скажите что это значит???

ANSWER
Hello, your thyroid hormone levels are within normal limits. For a complete examination, do an ultrasound of the thyroid gland.

Utfkyugoijp Fuygh
Good afternoon, I am 34 years old, height 1.62, weight 58kg (before the raw food diet was 60) I passed tests for thyroid hormones, could you see what is wrong: T3 total-1.09 T3 free. 3.27 T4 total 6.54 T4 free. 1.21 TSH (Thyrotropin) 2.280 AT-TG 45.9 AT-TPO 12.36, in addition, I became very irritable, I developed severe sweating, fatigue, depression for several years (the last 2.5 years I have been taking afabozol and it has become a little easier), periodically occurs interruptions of the heart in the form of extrasystole, increased fatigue, a history of urolithiasis, hr. pyelonephritis, cystitis, I had constant constipation for as long as I can remember from childhood (now I switched to a raw food diet and there are no more constipations, but flatulence remains), at the same time I became very fussy, hyperactive, I constantly want to eat, regardless of nutrition, I have not yet contacted an endocrinologist.

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, your thyroid hormone levels are within normal limits. Slightly increased AT-TG, so redo this analysis after 6 months. You should do an ultrasound of the thyroid gland, because without it the examination cannot be considered complete. If the ultrasound reveals formations of more than 10 mm, then they will need to be punctured. The complaints you listed are often associated with thyroid disease, but they can also be symptoms of other problems. You should visit a general practitioner, a gastroenterologist, undergo an ECG or Holter ECG, talk to a psychotherapist.

Zulfira Fatikhova

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, if you have hypothyroidism, then its treatment should be under the supervision of an internal endocrinologist. For correction hormonal background use drugs L-thyroxine or Euthyrox. Their dosage depends on what your thyroid hormone test result is. If you take too much of the drug, thyrotoxicosis may begin. I do not recommend self-treatment of hypothyroidism, as this can lead to serious complications.

Question 12
Lyubov Polorusova
Removal of the thyroid gland at the age of 76 years. Is it possible?

DOCTOR'S ANSWER_ENDOCRINOLOGIST
Hello, if there are serious indications for the removal of the thyroid gland, and at the same time there are no contraindications from the side of the cardiovascular and nervous systems, then operations at this age are possible.

Question 13
Tatiana Mazurina
Hello, I am 53 years old. In October 2014, for the first time at 52, I was diagnosed with subclinical hypothyroidism, after donating blood for hormones, there were 2 results: TSH-6.3; AT-TPO-0. Weight 80 kg, height -160 cm. 7 years ago I was 60-62 kg. The endocrinologist prescribed me L-Thyroxin for 3 months at 0.25 mg - for 2 weeks, then 50 mg and a short time at 100 mg, but when tachycardia began and the electrocardiogram worsened -returned 50 mg. After 3 months, she ordered me to take only TSH. The result was 3.93 μIU / ml. I hoped that they would cancel or reduce the dose, but the doctor, on the contrary, increased it and diagnosed hyperthyroidism. Now for another 3 months I have to drink on even days - 50 mg, and on odd days - 75 mg. I would like to clarify with you whether thyroxine is prescribed for such indicators, with hyperthyroidism? Blood sugar was 5.1, now after treatment 5, 5, they say that it’s normal. During the treatment, the weight did not decrease. I don’t really want to drink hormones, but it’s inconvenient for the doctor to say, she says that it’s vital. I’m very afraid to quit hormones and get diabetes. Thank you in advance for your advice.

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, if I were you, I would visit another full-time endocrinologist, since the TSH result of 3.93 μIU / ml is the norm. With such data, you could not be diagnosed with hyperthyroidism. In addition, hyperthyroidism is treated not with thyroxine, but with tyrosol. Most likely, she wrote this diagnosis erroneously. The tactics in the management of patients with subclinical hypothyroidism is as follows: they achieve normalization of the TSH level, and then for a long time patients drink thyroxine (maintenance dose). Most likely, if you stop taking thyroxine now, your TSH will creep up again.
Regarding weight: if the weight has not decreased while taking thyroxine, then hypothyroidism is not the cause of increased body weight. Follow a diet and enter regular exercise. It will also help control blood sugar levels.

Question 14
Zulfira Fatikhova
I am 60 years old height 158 ​​weight 65 hypothyroidism how to treat correctly

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, proper treatment hypothyroidism depends on what complaints you have, what level of hormones in the blood, whether there are antibodies to TPO. Also results of US of a thyroid gland are necessary. Therefore, it is impossible to give specific recommendations for the treatment of hypothyroidism on-line consultations. One thing I can say for sure: if TSH is increased, and free T4 is reduced, then you should take L-thyroxine for a long time under the control of an endocrinologist and blood tests for hormones. The dose is selected by the doctor, based on the data of your examination.

Question 15
All Kapon
Good afternoon
I am 25 years old, I am planning a second child, I have been drinking duphaston for 3 months, since the cycle was with great delays. Donated blood serum for hormones from the 5th to the 9th day of the cycle, the result: TSH 2.390 μIU, thyroxine 83.72 nmol, luteinizing hormone 10.74 mIU, follicle-stimulating 3.83 mIU, prolactin 304.20 μIU, progesterone 1.80 nmol, dehydroepiandrosterone -sulfate 5.86, Antibodies to TP 282.80 IU. She did an ultrasound of the thyroid gland, the results: Not enlarged in size, normal location, isthmus 3 mm, right lobe 18 by 15 by 46 mm, V 5.9 ml, left lobe 16 by 12 by 44 mm, V 54.0 ml. The structure is heterogeneous with fields of reduced echogenicity without clear contours, echogenicity is evenly normal, the contours are not even, clear. No focal changes additional formations not detected, vascularization of the parenchyma within the normal range, peripheral lymph nodes are not changed. Conclusion: diffuse changes in the thyroid gland by the type of thyroiditis. Tell me what these results mean and is it possible to plan a pregnancy? I ovulate every month...

ANSWER OF THE DOCTOR-ENDOCRINOLOGIST
Hello, you have significantly increased antibodies to TPO. This suggests that in thyroid gland an autoimmune process occurs that disrupts the normal functioning of this organ. At the moment, TSH and thyroxine are within normal limits. This means that the thyroid gland copes and keeps the level of its hormones necessary for the body. You can get pregnant with this disease, you do not need to treat it yet. Every six months it is necessary to take TSH and T4 free, ultrasound once a year. At change of quantity of hormones in a blood address to the internal endocrinologist.
Also, you should be examined for an increase in dehydroepiandrosterone sulfate. The norm is 0.8-3.9 μg / ml (maybe your laboratory has other norms, but you did not indicate them). Donate blood for cortisol, do an ultrasound of the adrenal glands. This can be the cause of a violation of the cycle and the absence of pregnancy.

Endocrinologist answers your questions: 161 comments

    Good afternoon
    I am 25 years old, I am planning a second child, I have been drinking duphaston for 3 months, since the cycle was with long delays. Donated blood serum for hormones from the 5th to the 9th day of the cycle, the result: TSH 2.390 μIU, thyroxine 83.72 nmol, luteinizing hormone 10.74 mIU, follicle-stimulating 3.83 mIU, prolactin 304.20 μIU, progesterone 1.80 nmol, dehydroepiandrosterone -sulfate 5.86, Antibodies to TP 282.80 IU. I did an ultrasound of the thyroid gland, the results: It is not enlarged in size, the location is normal, the isthmus is 3 mm, the right lobe is 18 by 15 by 46 mm, V is 5.9 ml, the left lobe is 16 by 12 by 44 mm, V is 54.0 ml. The structure is heterogeneous with fields of reduced echogenicity without clear contours, echogenicity is evenly normal, the contours are not even, clear. There are no focal changes, no additional formations were found, parenchyma vascularization is within the normal range, peripheral lymph nodes are not changed. Conclusion: diffuse changes in the thyroid gland by the type of thyroiditis. Tell me what these results mean and is it possible to plan a pregnancy? I ovulate every month...

    Dear All Kapon,
    The answer of the endocrinologist to your question is posted on this page at number 15
    Thanks for the question.

    Good afternoon, I am 34 years old, height 1.62, weight 58kg (before the raw food diet was 60) I passed tests for thyroid hormones, could you see what is wrong: T3 total-1.09 T3 free. 3.27 T4 total 6.54 T4 free. 1.21 TSH (Thyrotropin) 2.280 AT-TG 45.9 AT-TPO 12.36, in addition, I became very irritable, I developed severe sweating, fatigue, depression for several years (the last 2.5 years I have been taking afabozol and it has become a little easier), periodically occurs interruptions of the heart in the form of extrasystole, increased fatigue, a history of urolithiasis, hr. pyelonephritis, cystitis, I had constant constipation for as long as I can remember from childhood (now I switched to a raw food diet and there are no more constipations, but flatulence remains), at the same time I became very fussy, hyperactive, I constantly want to eat, regardless of nutrition, I have not yet contacted an endocrinologist.

    Dear Utfkyugoijp Fuygh
    The answer of the endocrinologist to your question is posted on this page at number 10
    Thanks for the question.

    Hello, I am 53 years old. In October 2014, for the first time at 52, I was diagnosed with subclinical hypothyroidism, after donating blood for hormones, there were 2 results: TSH-6.3; AT-TPO-0. Weight 80 kg, height -160 cm. 7 years ago I was 60-62 kg. The endocrinologist prescribed me L-Thyroxin for 3 months at 0.25 mg - for 2 weeks, then 50 mg and a short time at 100 mg, but when tachycardia began and the electrocardiogram worsened -returned 50 mg. After 3 months, she ordered me to take only TSH. The result was 3.93 μIU / ml. I hoped that they would cancel or reduce the dose, but the doctor, on the contrary, increased it and diagnosed hyperthyroidism. Now for another 3 months I have to drink on even days - 50 mg, and on odd days - 75 mg. I would like to clarify with you whether thyroxine is prescribed for such indicators, with hyperthyroidism? Blood sugar was 5.1, now after treatment 5, 5, they say that it’s normal. During the treatment, the weight did not decrease. I don’t really want to drink hormones, but it’s inconvenient for the doctor to say, she says that it’s vital. I’m very afraid to quit hormones and get diabetes. Thank you in advance for your advice.

    Dear Tatyana
    The answer of the endocrinologist to your question is posted on this page at number 13
    Thanks for the question.

    Removal of the thyroid gland at the age of 76 years. Is it possible?

    Dear Love
    The answer of the endocrinologist to your question is posted on this page at number 12
    Thanks for the question.

    Good day!
    I am 15 years old, I recently started to notice dryness in my throat and pressure. I went through an ultrasound on the thyroid gland, the results showed changes (increase). They sent me to take hormones, the results are normal. (TSH 3.10ulU/ml, T3 2/20nmol/L, T4 91/0nmol/L, LH 94/24mlU/ml, FSH 5.86mlU/ml, Estradiol518).
    After that, there were no problems, maybe sometimes. But recently, I started to feel not very good. It’s like a lump in my throat, it’s very pressing and it hurts. Where to go next if good results are attributed to pretense. I repeat that there are changes in the ultrasound. Maybe there are assumptions about the disease. And is it all serious, postponed until later, or should we hurry.

    Hello, you do not write the results of the ultrasound. It is not clear how much the thyroid gland is enlarged. Maybe you live in an area that is problematic due to low thyroid iodine. Then the increase in the thyroid gland is associated with its enhanced work.
    Your complaints may be related to ENT disease, diseases of the esophagus or neurology. Consult a therapist and go through a standard general clinical examination.

    Hello! I am 40 years old. Height 153 cm, weight 70 kg. Ultrasound was diagnosed with autoimmune thyroiditis of the type of hypothyroidism (echogenicity is increased, the echostructure is heterogeneous, the contours are even). TSH 3.8 µIU/ml, free T4 19.0 pmol/l, anti-body TPO 0.3 U/ml. Q: Need treatment? Thank you in advance for your response.

    Hello, you do not need treatment, as the hormonal profile is in order. The indicator of "antibody to TPO" is also not increased. This suggests that you do not have autoimmune thyroiditis. Structural changes in the thyroid gland can be explained by a lack of iodine in the diet. Take iodomarin courses, once a year do an ultrasound scan and take a blood test for hormones. The thyroid gland can work normally for a long time even in the presence of structural changes. But this must be checked annually.

    Tell me if pregnancy and the birth of a healthy child at the age of 39 are possible with a diagnosis of aiitis with nodulation subclinical hypothyroidism

    Hello, your diagnosis is not a contraindication to bearing a child. But during pregnancy, you should follow all the doctor's recommendations and take L-thyroxine in the required dose. Before conception, thyroid nodules should be punctured if their size is more than 10 mm.

    Hello, Doctor! I'm worried about my son (13 years old), diagnosed with diffuse changes in the thyroid gland. stands from the age of 9. On ultrasound of October 2015, compared to last year, the volume of both lobes was increased (from 2.3-2.5 to 2.8-3.6). Total volume - from 4.8 ml to 6.4 ml. The follicles were 1.5-2 mm, now up to 4 mm. T4 St. - 12 (the norm is indicated - 11.5-22.7), and T3sv. - 6.73 (at the indicated rate of 2.7-6.5).
    The boy is very sweaty, his hair falls out. Concomitant diagnoses are dysmetab.nephropathy, calcium metabolism disorders, severe food allergy. He takes iodine active 100 mg for a long time. Recently discharged Calcemin. Tell me, please, why there was a sharp increase in follicles, are we being treated correctly and maybe some more examinations are needed?

    Hello, the enlargement of the thyroid gland can hardly be called pathological, since its size has not gone beyond the permissible limits. A sharp jump may be due to the hormonal changes that occur in the body of your child. A slight increase in T3 must be kept under control. I'm surprised you didn't get a TSH. If possible, go through this analysis. If the indicator is within the normal range, then hormonal treatment is not required. If it is lower or higher than the norm, then this is an occasion for an internal consultation with an endocrinologist. I can’t say anything about other diagnoses, since there are no data from laboratory and instrumental examinations. Get a blood test for parathyroid hormone. Find a competent full-time endocrinologist.

    Hello! I am 24 years old, height 167, weight 65. In September 2014, I donated blood for thyroid hormone, the result: TSH 6.11. (other parameters are normal). Complaints were of drowsiness, increased fatigue, weight gain, hair fell out badly, menstruation was very painful. The endocrinologist diagnosed me with primary subcompensation hypothyroidism, prescribed levothyroxine (during the year it varied from 12.5 to 25 mcg). During the year, the figure dropped to 5.45. November 2, 2015 donated blood, the result of TSH is 8.52. The above symptoms do not bother me at the moment, I feel good, my weight has decreased. The doctor said that “most likely the dosage turned out to be small”, diagnosed primary hypothyroidism, increased the dose of the drug to 50 mcg, repeated. A consultation was scheduled 3 months later. Please tell me why the indicator increased, because I took the medicine as prescribed, is it worth it to go through the additional. examination? As far as I understand, if the indicator has risen, the state of health should worsen, but nothing worries me.

    Hello, you should take L-thyroxine at a dose of 50 mcg. An increase in TSH levels indicates that the disease requires correction. At some point, the thyroid gland begins to produce less thyroxine and TSH increases. The absence of complaints may be due to the fact that you are taking L-thyroxine (it partially compensates for the lack of its own hormones and lubricates the overall picture). An additional examination is necessary - this is an ultrasound of the thyroid gland, a blood test for free T4 and antibodies to TPO.

    Hello! I wrote to you earlier - thank you very much for the advice! Passed extra. examination (in another hospital), as you recommended, donated blood for T4, antibodies to TPO, and also TSH. Result: TSH - 3.96 (with a norm of 0.23-3.40), T4 - 16.3 (with a norm of 10.0-23.2), antibodies to TPO - 413 (with a norm of 0.000-50.000) ; I'm waiting for my turn at the ultrasound.

    Help, please, to decipher results of analyzes (the endocrinologist at present on the sick-list). I feel good, but my voice suddenly began to disappear, my throat hurts, it tickles in it - what can I do?

    Hello, based on the results of the examination, you have a disease - autoimmune thyroiditis, subclinical hypothyroidism. At the moment, TSH is slightly elevated, but in combination with increased antibodies to TPO, this already requires treatment.

    Usually, the endocrinologist prescribes a small dose of Euthyrox. This contributes to the improvement of health status and will prevent further progression of the disease. Pass or take place US and visit or attend the internal endocrinologist.

    Hello. I am 35 years old, weight 55, height 160 cm.
    For three months I have been tormented by dizziness. Now low blood pressure 96/75 tachycardia 97. (Own 110/70). Dry skin, hair falls out and doesn't grow back. Incomprehensible trembling in the body. In my throat, when I put on a turtleneck, as if something is interfering, an incomprehensible taste appeared in my mouth. Hands and feet are cold, I get irritated, there was tearfulness for any reason.
    I did some tests and here are the results:

    TSH 1.8600 μIU / ml (after a month passed
    Ttg 1.81
    Т4 14.90 (in a month
    T4 free 13.52
    Т3 4.22
    Anti TOP 12..27 Me/co
    Prolactin 145.11
    Cortisone 19.2
    ACTH 23. Ultrasound of the thyroid gland pr. share 13.3 * 14.3 * 37.9
    Volume 3.8
    Left lobe 14*16*42 volume 5.1 isthmus 3.7 increased echogenicity. Fried. Pain in the joints in the knees. In 2001 it was Ait. Now I give birth to hypothyroidism at the beginning. Stages of teriotoxicosis and maybe Aitis?
    Answer please.

    …. HYPOTHYROISIS IS FOREVER!??
    I have hypothyroidism against the background of AIT…….. for 22 years now.
    I take Thyroxine -100 mcg. Against the background of this reception, all hormones seem to be normal; TSH-1.15 mU/l (0.4-4.0)
    T4 St.-16.4 pmol / l (9.0-22.0)
    T3-1.1pmol/l (2.6 -5.7)……RS: As far as I know, if TSH is normal and T3 is low, then it is considered a 100% laboratory error!?
    AT to TPO-159.1 (increased, but this is understandable, because AIT)

    Ultrasound: Echo-signs of diffuse changes in the structure of the thyroid gland. In the area of ​​the isthmus-nodule 2-3 mm.
    Please, doctor, tell me: 1). Such a small volume of the gland ... how bad is it? (because in 2009 she was 5.9 cm; in 2006 -16.9 cm, and now she is quite small). I did not do the operation! 2). What are my hormones and ultrasound saying?
    3). I want to drink Reduxin 10, because extra 15 kg. How do thyroxine and sibutramine interact?
    Thank you in advance, you are doing a good job, helping us understand all the intricacies of the tests ... and in general, with practical advice on what to take, where to run ....! Looking forward to your reply. Thank you!

    Hello, tell me please! Has handed over analyzes TSH, Т4 svob. due to the fact that there was weakness, tearfulness, mood swings, nervousness and tachycardia (ultrasound of the heart, kidneys and adrenal glands - normal, ECG - normal). TTG - 6.3 T4 - 15.5 Ultrasound of the thyroid gland showed CHAT. Endocrinologist's diagnosis: CHAT, subclinical hypothyroidism, first diagnosed. Has registered a L-thyroxine 25 mg. I take it for 5 days, the condition does not improve, on the contrary, weakness, low blood pressure (105/65, 95/60), internal shaking, heavy head. I called the doctor, he said it was addictive. Tell me how much days go by addiction to the drug, what are the symptoms? Maybe 25 mg is too much for me? I understand that the numbers are not very high. The first 3 days was a terrible nausea. At the moment I am taking: L-thyroskin 25 mg (in the morning on an empty stomach) Tri-regol (in the evening) Coraxan 5 mg (for tachycardia) (morning and evening).
    Today they called an ambulance, severe weakness, the head was like in a hat with earflaps (it pressed on the temples on the forehead and laid the ears), while the pressure was normal and the ECG was also (the doctor did it with the ambulance). He says that perhaps these pills do not suit me. Today I took only L thyroxine in the morning and that's it, because weakness began an hour later, I did not take Coraxan, so as not to blur the picture. What to do, I can not understand. Can I take nothing at all from the hormone?????

    Hello, lack of thyroid hormones is a serious condition that needs to be corrected. At the beginning, the symptoms are not very pronounced, but the neglected disease leads to many consequences, some of which are irreversible. My opinion is that you should continue taking L-thyroxine at the same dosage. Try to get Eutiroks. These two drugs differ in the content of excipients. The active ingredient is the same. Therefore, the dose does not need to be adjusted. Continue treatment for a month. Then you need to take a blood test for hormones, and evaluate the result. Perhaps in a month your complaints will pass, as the body adapts to the new hormonal background.

    Thanks for your reply! During this time, she stopped taking L-thyroxine altogether, as her condition only worsened. Now, for almost 10 days, I have not been taking the drug and is just starting to “let go”. It was a terrible condition: and squeezing the head, numbness of the crown, cheekbones, ringing in the ears, shaking hands. Terrible depression. I was at the appointment of an endocrinologist, they said that I had an individual intolerance to the drug. They advised me to take tests again later, and there they will already adjust the dose. Most likely I will resort to your advice and I will take Eutiroks.

    I am 26 years old, height 168, weight 55 kg. I am planning a pregnancy. I did an ultrasound of the thyroid gland, everything was normal. Has handed over analyzes TTG 4,93; T4 - 110.6; T3 - 2, 0 . Is it possible to plan a pregnancy with such tests? In connection with what such analyzes can be? And tell me, do I need to drink thyroxine and what should be the daily dose?

    Hello, your TSH is slightly increased. It is not entirely clear whether you took a blood test for T4 total or free. Based on the fact that TSH is not much more than the norm, I will assume that this is a general T4. Then it's the norm. The increase in T3 (this is most likely "free") is insignificant.
    My recommendations: retake a blood test for TSH and T4 free hormones and contact an internal endocrinologist. The most favorable course of pregnancy occurs at the level of TSH 2.0-3.0. Therefore, if the second TSH test is also higher than normal, then you should start taking small doses of L-thyroxine. This will have a beneficial effect on your health and will accelerate the onset of pregnancy.

    Good afternoon. My son is almost 7 years old, the conclusion of ultrasound is diffuse changes in the thyroid gland. How serious or dangerous is the picture? Is it possible for him to do karate until we get to the endocrinologist, how can we support the body? Right lobe 13.0mm*12.0mm*30.0mm volume 2.2cm3; left lobe 12.0mm*10.0mm*30.0mm volume 1.7cm3
    Isthmus 2.0 mm; location is normal; the contour is even, clear; the capsule is not sealed; mobility during swallowing is preserved; the echostructure is homogeneous; features: anechoic inclusions are determined in both lobes; blood supply is normal; regional lymph nodes are not enlarged

    Hello, similar changes can be in the results of ultrasound with a lack of iodine in the body. I recommend iodomarin 100 mg once a day. Also do a blood test for TSH, T4 free and antibodies to TPO. If the hormonal background is within the normal range, then drink jodomarin for a long time and repeat the examination in a year.

    Hello. Daughter is 11 years old. Independently turned to the endocrinologist. I noticed a visual enlargement of the thyroid gland. They passed the tests: T4-1.04 is normal, TSH-2.4753 is normal, an increase in AT-TPO-748.28 (at a rate of 0-6). Ultrasound: hyperplasia, diffuse changes, increased blood flow. The volume of the thyroid gland is 17.9 ml. My daughter is 11 years old, weight 38, height 156 cm. (according to WHO). Treatment: l-thyroxine 50 mcg, under the control of hormones every 2 months. Taken throughout the year. AT-TPO gradually decreased. The volume of the shield has slightly decreased. wish. Now: T4-0.94 norm, TSH-0.5975, AT-TPO-121.56. Ultrasound: hyperplasia, diffuse changes, no increase in blood flow. But the volume is a shield. wish. increased by 1 ml. The doctor prescribed a control test for hormones and ultrasound for 3 months. She said we will increase the dose of l-thyroxine to 75 mcg. My question is: Is my child treated correctly? Do I need to consult another endocrinologist? Thank you.

    Hello Svetlana.
    The treatment you are receiving is correct. In your case, L-thyroxine in small doses has some sedative effect to the thyroid gland. She does not have to “work” a lot in order to have enough hormones for all the needs of the body. So keep taking the drug. The result is positive. TSH is now at the lower limit of normal. Further increase in the dose of L-thyroxine can lead to hyperthyroidism. But at the same time to prevent further growth thyroid volume. Therefore, if the next ultrasound will increase the volume, then you can try taking 75 mg of L-thyroxine. But you need to carefully monitor the well-being of the child and immediately donate blood for TSH at the slightest change.

    Thank you. We will closely monitor our well-being. Tell me, are iodine preparations contraindicated for a child? During the year, I even bought multivitamins for my daughter Bay Yoda.

    Hello, I have never been to an endocrinologist, at the 16th week of pregnancy I passed an analysis for thyroid hormones ttg-1.74, free t3-4.47, free t4-19.31, thyroglobulin 3.86. The doctor said everything is normal. I took iodomarin 200 a month before the test, could it affect a good result? Thank you

    Hello, lack of iodine in the human body can be in the absence of obvious problems with the thyroid gland. Conversely, some diseases occur with a normal iodine content. Therefore, all pregnant women are prescribed iodomarin, even if the hormonal background is in order. This is the prevention of intrauterine fetal pathology. Your hormones are in order, you drink iodomarin. Continue taking the drug throughout your pregnancy and breastfeeding. TSH can be repeated at 30 weeks pregnant. And do not forget to regularly take a blood test for glucose - it should be no more than 5 mmol / l.

    Thank you very much! Thanks for the prompt response! All the best to you! I wish from the bottom of my heart.

    Good afternoon. I turned to the local endocrinologist, was sent for testing - as a result of TSH 5.056, free thyroxine 0.79. right lobe, hypoechoic node 8.0 * 6.0 * 7.4 in the right lobe. L-thyroxine was prescribed at a dose of 50 for the first 10 days, and then switched to a dose of 100 - 3 months, another Yosen 1 tablet at night and thyroid tea .After 2.5 months I felt weakness, dizziness, a drop in blood pressure, palpitations. We repeated the analysis of TSH - it fell to 0.014. The doctor said to switch to a dose of 75 and drink for 2 more months, if the condition does not improve, reduce the dose to 50. But the condition is now bad Are we doing everything right?

    Hello, the treatment is correct. Switch to the dosage of L-thyroxine 50 mg. Control of TSH in a month from the start of taking the drug at this dose.

    Hello! The result of TSH is 3.16 (we are planning a pregnancy), ultrasound of the thyroid gland is all normal, the doctor prescribed Thyreocomb, but it is not realistic to find it, there are no analogues for it either. What to do? What can replace it?

    Hello, you should visit the endocrinologist again in order to correct the treatment. If you are planning a pregnancy for more than a year, then you should start taking the drug as soon as possible. The ideal TSH level for conception is 2.5 mIU/L.

    Hello! I am 31 years old, height 169cm, weight 106kg. The thyroid gland was enlarged at school, but there were no problems with weight. I recovered in 2008 with my first child up to 100 kg, then I lost weight to 80 kg. After the second child, I can not lose weight, constant weakness, frequent dizziness. The endocrinologist put D / z: Autoimmune thyroid, goiter 2 st., Hypothyroidism, obesity 2 tbsp.
    Latest analyzes: TSH - 4.90; T4sv - 11.20, T3 total. - 1.49; ATkTPO - 234; Prolactin -242, glucose - 6.44. Hemoglobin - 98. Help with treatment (now I do not take anything, the second child is a year and a half)

    Hello, your TSH is slightly increased, which indicates the presence of hypothyroidism. These TSH numbers rarely lead to significant weight gain, since your thyroid levels are not yet reduced. You need to start taking hormone replacement therapy. Only an internal endocrinologist can prescribe a dose of hormones. Watch your diet, try to move more. Losing weight is impossible without diet and exercise.
    Low hemoglobin levels are the cause of your dizziness. You should take sorbifer 1 t twice a day for a long time.

    Hello!
    I had an enlarged thyroid when I was a child. She was registered, iodomarin was prescribed. Now we are planning a pregnancy, but not yet. Passed tests, ultrasound. The doctor said that everything is normal. Can conception not occur if it was enlarged in childhood, but now it is not? Thank you!

    Hello, if the thyroid gland was enlarged without changes in the hormonal background, then this cannot be the cause of infertility. Now you need to take a blood test for TSH, T 4 free and antibodies to TPO. This will clarify the situation with your hormones. You can also be examined for LH, FSH, estradiol, progesterone, prolactin and cortisol (it makes sense to pass these tests if pregnancy does not occur for more than 6 months).

    Hello! My mother is 76 years old. With TSH readings of 3.4, the endocrinologist prescribed l-thyroxine at a dose of 0.25. Ultrasound results, nodular goiter on the background of thyroiditis. Please tell me your opinion about the prescribed treatment? Thank you.

    Hello, there is an opinion that small doses of thyroid hormones can prevent a further inflammatory process, which in any case will lead to hypothyroidism (it is difficult to say the timing, everyone has a disease in different ways). The dose is very small, supportive. Therefore, there should be no undesirable effects from taking hormone replacement therapy. Visit another full-time endocrinologist, since full-fledged advice can only be given after examining the patient and getting to know her medical history.
    You do not write what size the node in the thyroid gland is. If it is more than 10 mm, then I recommend to puncture the node with a biopsy.

    Hello, I am 29 years old, weight 55 kg, height 168. I am preparing for pregnancy and therefore I took hormones. Results in August antibodies to thyroid peroxidase 12.5 (normal 0-30); ttg 3.64 (normal 0.23-3.4); svT3 4.42 (norm 2.5-7.5); LG 5.4 (norm 1.1-8.7); FSH 7.7 (normal 1.8-11.3); Prolactin 406.2 (normal 67-726); estradiol 101.6 (norm 15-120); free testosterone 0.7; fT4 9.5 (norm 7.86-14.41) progesterone 20.20 (norm 1.2-15.90). It seems that everything is fine with the tests, TSH and progesterone are slightly increased. But progesterone can be increased due to hormones (drank proginova and Divigel), as there were problems with the cycle and planning pregnancy. But the doctor also prescribed me Euthyrox 25 ml to drink 1 tablet in two days. In September, she drank only Euthyrox and vitamins and iodine 100 ml, passed tests in early October and TSH 6.72 (normal 0.23-3.4) and progesterone 94.3 (normal 16.4-59). Please tell me Why TSH almost doubled in a month? And how to plan pregnancy now? Whether it is necessary to continue to drink Eutiroks? And iodomarin in combination with euthyrox could not complicate the situation? Thanks in advance for your reply.

    Hello, you should do an ultrasound of the thyroid gland and visit an internal endocrinologist. An increase in TSH while taking Euthyrox indicates that the thyroid gland produces an insufficient amount of hormones, and the dose of the drug is not enough to compensate for your condition. You need a correction of the treatment (increase in the amount of Euthyrox) after the examination and additional examination. It is impossible to plan a pregnancy against the background of high TSH, as this can lead to serious intrauterine pathology in the fetus. There is evidence that iodomarin should not be taken with autoimmune thyroiditis. You need additional examination to decide whether to continue taking Iodomarin.

    Good afternoon. The diagnosis is primary subclinical hypothyroidism. Pregnant 7 weeks. Before pregnancy, I had a TSH of 2.33, I drank l. thyroxine 50, now, after I found out that I was pregnant, I increased the dose of l. thyroxine by 2 times. Ttg 1.45 (this is what the endocrinologist said to do). The gynecologist prescribed Duphaston 1 tab 2 times a day. Tell me, is the TSH not low (according to the laboratory parameters, the norm is 0.1-2.5), is it possible to drink duphaston?

    Hello, an increase in the dosage of L-thyroxine is justified, since during pregnancy the need for hormones increases. You should retake a blood test for TSH in a month so as not to overlook hyperthyroidism (it is also dangerous for the fetus).
    Regarding the use of duphaston - this is medicinal product with specific indications for use. It has nothing to do with the treatment of hypothyroidism. It is used for threatened miscarriage, recurrent miscarriage and other conditions. Discuss with your gynecologist the purpose of taking the drug, since without a personal examination and questioning, I cannot comment on the prescription of the drug.

    Hello, at the 12th week of pregnancy TSH 3.53, T4sv 8.93. How serious are these discrepancies, is it worth worrying too much? Before that, I had never taken an analysis for these hormones. In addition to vitamins, I take iodomarin, and at week 15 I was prescribed l thyroxine 50 mg. Until I started taking it. I have never dealt with hormone preparations before. Will I be able to stop drinking this hormone later, or as I read in some sources, it is for life.

    Hello, pregnancy is a special state of a woman's body that requires increased work. internal organs and systems, which is necessary for the normal development of the fetus. In your case, an increase in the level of TSH above 2.5 indicates that the thyroid gland is not coping with its function. This leads to the fact that the child develops in conditions of subclinical hypothyroidism. The lack of horions of the thyroid gland can adversely affect the development of its nervous system and the whole organism as a whole. You should visit a full-time endocrinologist to decide on the appointment of replacement therapy, dosage of the drug and further monitoring of health throughout pregnancy.
    Do an ultrasound of the thyroid gland, as well as general analysis s blood and urine before visiting a doctor.

    Hello, I am 27 years old, an endocrinologist diagnosed me with autoimmune thyroiditis, hypothyroidism. test results:
    AT to TPO - 125.4 IU / ml
    TSH- 101.8 µMe/ml
    T4- 4.14 pmol / l
    Tell me, is this condition of the thyroid gland possible after childbirth (7 months ago) and can there be further normalization of hormones after treatment?

    Hello, autoimmune diseases often found after childbirth, since during pregnancy there is a significant restructuring of the body. The immune system also suffers. You definitely need to take hormone replacement therapy, because the level of TSH is very high. Hypothyroidism is chronic illness requiring long-term treatment. It is not necessary to cancel hormones on your own in any case. Normal level TSH against the background of treatment suggests that the dose of hormones is well chosen. But this does not mean that the thyroid gland has restored its work.
    Pay attention to the health of the child. Most likely, hypothyroidism began during pregnancy, and this could affect the functioning of the baby's thyroid gland.

    Hello! I am 45 years old, height 164 cm, weight 67 kg. For several years I have been living with a diagnosis of autoimmune thyroiditis. In June, hormones: TSH -1.36, AT TG -54.2. Last ultrasound results a week ago: right lobe 1.8 * 1.5 * 2.9 V -1.3 echo structure is heterogeneous, echo density is uneven, nodal pattern 0.7 * 0.5 mm is visualized in the structure 4*1.3*3.6 there was no nodule), left lobe 1.4* 1.1* 2.2 V-1.8 Isthmus 0.37 Volume 3.1 increased echogenicity. Conclusion: Hypoplasia of the thyroid gland Differential changes in the parinchyma. The doctor prescribed L-teroxin from a dose of 50 to 25, at the same time Iodomarin 100 and endocrinol 2 tablets during breakfast. How do you think? Thank you. I want to add: there is uterine fibroids with progression

    Hello, dear doctors) for a child of 8 years old, the volume of thyroid gland is normal, increased by 1 unit TSH, cholesterol, T3 and T4 St. are normal. The doctor prescribed Iodomarin 150 for 2 months, repeat TSH, give another 4 months and do ultrasound and TSH. His weight is 32, height 135. What do you think, should I give iodomarin or not? Maybe it's worth giving 100? By the way, the antibodies are normal.

    Hello, you should take a second blood test for TSH, since the June one is no longer informative. The situation with treatment is not absolutely clear. You had a dosage of L-thyroxine 50 micrograms and the doctor lowered you to 25 micrograms? Correction of hormonal treatment could be carried out only on the basis of fresh analyzes for TSH. The appearance of a node is not a reason to reduce the dose. This is a reason to do an ultrasound once a year to monitor the growth of the nodule. When it reaches 10 mm, it will be necessary to undergo a puncture under ultrasound control. Take Iodomarin, and Endocrinol is a dietary supplement. So, its effectiveness and safety has not been proven.

    Hello, iodomarin will definitely not harm a child, especially if you live in an area with a reduced amount of iodine in the environment. The only question is whether an increase in the amount of iodine in the body can compensate for the reduced amount of thyroid hormones. If hypothyroidism is caused by a lack of iodine, then iodomarin is the only way to help the patient. In other cases, it will not be effective.
    If the patient has non-specific complaints (drowsiness, decreased performance, weight gain, constipation), then these are signs of subclinical gyrothyroidism. Then you should think about the appointment of hormone replacement therapy. If there are no symptoms of the disease, then you can take iodomarin and control TSH.

    Thank you! Today retaken TTG, by results I will unsubscribe.

    Good afternoon.
    I am 30 years old. I am breastfeeding a 4 month old. From the very beginning, there was a little lack of milk, now it has become even less. No advice from breastfeeding experts helps.
    But 2 times there were cases when milk flowed like a river (the first time - ovulation by ultrasound, the second time - 40 days after the first). There is a lot of milk for 2 days, and then again it is not enough. I'm guessing prolactin deficiency. Drugs that enhance lactation help, but they give me a wild headache.
    Can I take Utrozhestan or duphaston to maintain lactation?

    Good day! TSH 5.07 IU/L, FT4 13.86 pmol/L, FT3 3.57 pmol/L. I feel bad at a dose of 25 mcg, suffocation in the thyroid gland, headache, weakness. What do you think, go back to the dose of 50? Thank you.

    Hello, Utrozhestan and Duphaston are contraindicated during breastfeeding, as they pass into breast milk. These are hormonal drugs, so their presence in the baby's body will harm his health. If you last 4 months, then there is a chance that you will breastfeed your baby for up to a year. If you are formula feeding your baby, then I recommend stopping for a while. Offer your baby only the breast, and do it as often as possible. Night feedings must be present, and the amount of fluid you drink is at least 2 liters.
    Your attitude shows that you want to keep breastfeeding. It is very important not to lose hope. After two months, you will be able to start complementary foods, which will make your life much easier.

    Hello, TSH is clearly less than normal. You should increase the dosage of L-thyroxine to 50 mcg and repeat the TSH in a month.

    Thanks for the answer.
    Tell me, is it possible now, when breastfeeding, to undergo an examination and find out the cause of reduced Prolactin (if there is still a decrease)? Does it make sense to take an analysis for the level of Prolactin? I have read that sometimes low prolactin levels are due to specific health problems.
    I breastfed my first child with no problems.
    Thank you in advance

    Hello, you can take a blood test for prolactin. But even with its decrease, it will be difficult for you to pass a full examination. Most often, problems with breastfeeding occur due to stress, lack of sleep and fatigue. This affects the hormonal system in general, and in particular, the level of prolactin. Contact your local physician and undergo standard tests (complete blood count, urinalysis, biochemical analysis blood). Together with prolactin, you can check the thyroid gland (hormone TSH).

    Thanks a lot

    Hello, Doctor. I am 32, height 168, weight 63, I plan to do IVF. I passed an analysis for TSH, the result: 3.65, I took iodamarin, after 1.5 months: TSH 3.45. My gynecologist said that for IVF it is necessary that TSH be no more than 2.
    Eutirox 25mg was prescribed. From this drug, an allergy began: the whole face was covered with acne, Euthyrox was replaced with L-Thyroxin 25, and this started to constantly hurt my head, and I feel constant drowsiness. Please tell me what should I do?

    Hello, did you have allergic reaction not on the component itself, but on the additional substances that make up the tablet. Therefore, when you changed the drug, you no longer had a rash.
    There may be slight discomfort at the beginning of treatment with L-Thyroxine. Do a blood test for TSH in a month from the start of treatment. During this time, the body adapts to the new hormonal background.

    Good afternoon Tell me please. I am 27. weight 60 height 168. I am planning a pregnancy TSH 2.96 (the norm is supposedly up to 4), but the doctor said that 2.50 would be necessary. while 17 alpha oxyprogesterone is 0.91 (the norm is up to 0.8). do these indications require further treatment or is my doctor (gynecologist-reproductologist) insured?

    Hello, the doctor must respond to changes in the analyzes, since this is precisely what examinations are for. Especially when it comes to reproduction. In your case, if you are not preparing for IVF, if you have not had “failed” pregnancies or have not conceived for last year, then you can plan a pregnancy. If the gynecologist prescribes further tests, then he has the right, especially with respect to 17 alpha oxyprogesterone.

    Hello! My daughter is 17 years old, irregular menstrual cycle, in June 2016 she was sick infectious mononucleosis. They passed the tests on the 11th day of the cycle on January 13, 2017: TSH - 4.53; free T4 - 1.14; free T3 - 3.34; anti-TG, 17.1; FSH - 6.77; progesterone - 0.20; prolactin - 17.46; estradiol - 67.54; cortisol - 13.4; total testosterone - 1.83; HCG - 1.00. The endocrinologist immediately prescribed to take L-thyroxine 25 mcg. Is it correct? Answer please!

    Hello, the tactics of the endocrinologist are correct. Your daughter needs treatment because her TSH is higher than normal. This may be the cause of her menstrual problems. Postponed mononucleosis does not affect the functioning of the thyroid gland.

    Hello. My daughter is 15 years old, irregular menstrual cycle, cyst of the left ovary, prescribed treatment and tests for hormones. TSH-3.74, prolactin-15.67, testosterone 1.12. The indicators seem to be normal, but on the verge. worries about TSH, since I have hypothyroidism myself. How not to miss it.

    one more question. my TSH from August 2015 to April 2016 at a dose of Euthyrox 50 fell from 9.22 to 2.5. Increased the dose to 75. Now TSH-0.73. whether to return the dose of 50?

    Hello, if you have AIT, then your daughter may also develop this disease, since genetic predisposition matters. But more than once a year, you should not check TSH (provided that you feel well and there are no complaints).
    Regarding your health - if there are complaints (heartbeat, bad dream, irritability, etc.), then it is necessary to reduce the dosage of the drug. If there are no complaints, then you can continue to take 75 mcg. Three months later, TSH control.

    Hello! I am 28 years old, trying to conceive, ovulation tests are negative. TSH-5.96. According to gynecology, everything is normal. A diagnosis of hypothyroidism was made. I have been taking Euthyrox-25 for 2 weeks. Now are favorable days for conception. Should I try to conceive a child and do foloiculometry, or is it better to wait? Thank you in advance for your attention!

    Hello, it's better for you to do a blood test for TSH in a month on the background of treatment. If the result is within the normal range, then you can safely plan a pregnancy. But you should not stop taking the drug, as the TSH will return to the previous numbers again. It is necessary to take L-thyroxine throughout pregnancy and breastfeeding, and always under the control of TSH once every three months.

    Thanks for the answer! I am very worried about the lack of ovulation (negative tests). In gynecology, everything is fine: both tests and OMT ultrasound, no infections. Can hypothyroidism cause a lack of ovulation?

    Hello, it is not for nothing that gynecologists prescribe a blood test for thyroid hormones to all planning and already pregnant women. Even a slight hypothyroidism that does not cause serious complaints in the patient (weakness, drowsiness, constipation, weight gain, memory loss, etc.) can lead to infertility. And in pregnant women, this condition can lead to a missed pregnancy, intrauterine growth retardation, and serious abnormalities in the nervous system of the fetus. Therefore, it is important to know the level of TSH and T4 free in preparation for pregnancy, and even more so in case of problems with conception.

    Hello, they said to take euthyrox 25 mcg, and after 4-6 weeks, do a TSH control and come with the results, if you take tests and stop drinking euthyrox a week before the doctor's trip, is that possible?

    Hello, if you stop taking the drug, then the TSH will return to the previous numbers that were before the treatment.
    The point of monitoring TSH is to see if 25 mcg of ectirox is enough for you. If TSH during treatment is higher than 4, then the doctor will increase the dosage of the drug.
    It should be remembered that l-thyroxine is hormone replacement therapy. It does not affect the cause of the disease and does not restore the functioning of the body. Therefore, it is not worth expecting that the thyroid gland will suddenly work on its own against the background of euthyrox.

    Hello, I am 26 years old, I recently underwent an ultrasound of the thyroid gland, it turned out that there are nodules on the right side. I passed tests for hormones TSH - 14.10, Free T4 - 1.05, Anti TPO - 404.2, before that I did not take tests for hormones and now .... married, 1.5 years I can not get pregnant. The endocrinologist prescribed L-teraxin 50 - 2 weeks, and 3 months L-teraxin 75 without explaining anything. Whether tell or say please I can reduce hormones for such period of time? the question that worries me the most after I bring my hormones back to normal will I be able to get pregnant? Thanks a lot.

    Hello, most likely, the cause of infertility is hypothyroidism. At the moment, you should use protection, as an accidental pregnancy on the background of hypothyroidism can end unfavorably (spontaneous miscarriage, intrauterine growth retardation).
    Treatment is based on hormone replacement therapy with L-thyroxine. It is necessary because your thyroid gland has stopped producing its own hormones. This happened due to the fact that an autoimmune process is going on in the tissue of the gland, which gradually destroys the structure of the organ. This leads to a decrease in the production of the main hormones - thyroxine and triiodothyronine. As a result, many body functions are disrupted, in particular, the ability to conceive.
    The hormonal background will return to normal if the dose of L-thyroxine is chosen correctly. It is difficult to immediately “guess” the correct dosage, so the doctor prescribed you a control after three months. If TSH is normal by this time, then you can safely plan a pregnancy. In no case should you stop taking L-thyroxine when the level of hormones is normal, since TSH will rise again, and T4 will fall.

    Hello! I mistakenly gave a 3-year-old child L-teroxin instead of glycine, what will happen now?

    Good afternoon,
    I am planning a pregnancy, I visited a gynecologist-endocrinologist,
    Donated blood. Results:
    TSH 1,650 mIU/L
    Т4 sv 8.95 pmol/l
    AntTPO 1 IU/ml
    Prolactin 12.3 µg/l
    Estradiol 23 ng/l
    The doctor prescribed L-thyroxtine 25 for 3 months.
    Then I went to the clinic and the doctor says that everything is normal and you don’t need to drink anything.
    I have been taking the drug for 3 weeks. My condition has improved a lot. Your advice: stop taking or follow the appointment of a gynecologist.
    Thank you in advance

    Hello, in such cases, you need to call ambulance or independently organize a gastric lavage.
    If you didn’t do this right away, then watch the child ( arterial pressure, pulse, mood, sleep). The reaction depends on the weight of the child and the dosage of the drug. If you see changes in health, then call an ambulance.

    Hello! Thank you! I didn’t notice any changes - on the contrary, my mood is good, I sleep well, although it seemed to me that she became calmer - she was nervous, hysterical all the time - therefore she gave glycine, and then for two days a miracle child.

    child weight 15 kg and dosage 50

    Good afternoon! Height 1.50 weight-43
    I am planning a pregnancy, in December TSH-5.42, the doctor diagnosed hypothyroidism and prescribed eutiroks 25. After 2 months in March, on March 7, 2017, I passed TSH-3.50 μIU / ml (at a rate of 0.40-3.77),
    T4 free-1.19 (at a rate of 1.00-1.60), Anti TPO-6.72 (at a rate of 34).
    Ultrasound of the thyroid gland: The contours are even and clear. The location of the gland is typical. Echogenicity is normal. The capsule is continuous. The isthmus is 0.3 cm not thickened. The right lobe is 4.3 * 1.2 * 10 cm.
    left share size 4.2 * 1.4 * 1.1. Volume 3.8 cm cubed.
    Conclusion ultrasound of the thyroid glands: Echographically small cysts with calcification of both lobes of the thyroid gland. Nodular formation of the left lobe of the thyroid gland (According to WHO, the norm for women is from 4.4-18 cm cubed).

    Hello, tell me, if TSH is elevated, can this lead to an increase in cholesterol levels?

    Hello, tell me please. Nothing worries except for the temperature of 37, which has been holding on for more than a month after a decrease in immunity and frequent colds. Lymphocytes are increased and neutrophils are lowered as a percentage, in the unit of measure 10-9 / L, these same indicators are normal, as the doctor said, this is a sign inflammatory process in the body, from it and the temperature. Platelets are increased -373 at a rate of 180-320 (although in many laboratories the norm is up to 400). Other analyzes (biochemistry and urine) in norm or rate. I haven’t taken hormones yet, I did an ultrasound of the thyroid gland (the therapist recommended contacting an endocrinologist). Description:
    Isthmus 2 mm. The structure is moderately heterogeneous, the echogenicity is normal, the nodes are not located. The right lobe is 21x17x53 (volume 9.1 ml). The structure is moderately heterogeneous, the echogenicity is normal. In the central parts of the lobe, a hypoechoic node 8x4x7mm in size with clear contours is located along the posterior surface. The blood flow in the parenchyma of the gland is not increased. The left lobe is 21x14x51 (volume 7.2 ml). The tissue structure of the lobe is pronouncedly heterogeneous with the formation of a pseudonodal transformation, echogenicity is normal. True nodes are not located. The total volume of the thyroid gland is 16.3 ml. Regional lymph nodes: the lymph nodes of the jugular groups are not enlarged, with a typical echostructure. In the paratracheal region, hypoechoic lymph nodes sized 7x7x12mm, 11x4mm, 12x4mm, 8x3mm are visualized predominantly on the left. Cervical lymphadenopathy. Recommended: blood test for TSH, free T4, calcitonin, ionized calcium, parathyroid hormone, antibodies to thyroglobulin, antibodies to thyroperoxidase. Can you please tell me why there are so many tests? Usually, they only give TSH and it seems to be T3 and T4, but I have such a set, is it really necessary to pass all these tests in my situation or, for a start, can I get by with some specific tests and not in such quantity? And can there be a temperature due to problems with the thyroid gland, given that the temperature appeared with frequent colds after a decrease in immunity and has remained and is holding on? Thank you in advance and I look forward to your reply. Sorry if there is a lot of text, I wanted to describe the situation in full.

    Hello,
    My daughter is 21 years old. Height 162, weight 63. Menstruation from the very beginning (from the age of 13) was irregular. 4 years ago, after the appointment of dysmenorm, the cycle was adjusted, a year ago the cycle was disturbed again, the examination revealed polycystic ovaries, they prescribed Jess + (he still takes it), then testosterone was increased, the rest of the hormones are normal. The cycle returned to normal, on ultrasound the ovaries are already normal without traces of polycystic, there are no side effects, testosterone was retaken - the norm. Six months ago, noticed a constant increase in body temperature. All sorts of examinations were carried out, which did not reveal anything. Two months ago, they passed hormones - TSH 4.02 FT4 16.42 TSH 3.61. The endocrinologist prescribed L-thyroxine 25 mg for 2 months, but said that low-grade fever could be associated with the thyroid gland and after 2 weeks of taking the temperature may decrease, but this did not happen. 2 months passed, tachycardia appeared, TSH was retaken 3.96, it practically did not decrease. The endocrinologist increased the dose to 50 mg and said to retake after 6 weeks. Tell me, please, is such treatment adequate and is there a need for additional examinations or may I need to turn to another endocrinologist?

    Hello, you can plan pregnancy, as TSH is currently within the normal range. You can not stop taking the drug, because TSH will increase again. It is necessary to continue taking the drug throughout pregnancy and breastfeeding. If pregnancy does not occur within three months, then it is worth taking a blood test for TSH again. Conception is best when TSH is less than 2.5 mU/L.
    When pregnancy occurs, it will be necessary to immediately do a TSH (make sure that the result is within the normal range), and then take an analysis once every three months for control.
    With regard to ultrasound - control once a year with monitoring the growth of the nodule (in this conclusion you did not indicate its size). If they are more than 10 mm, then a puncture of the formation should be made under ultrasound control.

    Hello, a change in TSH indicates a malfunction endocrine system. And she is responsible for many processes in the body, including lipid metabolism. An increase in TSH occurs with hypothyroidism, and the main problem of this disease is a slowdown in metabolic processes. Cholesterol, which comes from food and is formed in the liver, should normally perform its physiological functions (embedded in the cell membrane, participates in the synthesis of sex hormones, etc.). With a decrease in metabolism, cell renewal processes slow down, respectively, its consumption decreases, which leads to its increase in the blood. Very high cholesterol numbers are rarely caused by gyrothyroidism alone, so you need to adjust the TSH level, review your diet and lifestyle.
    If hypercholesterolemia persists, it is necessary to resort to medical correction with statins. High cholesterol leads to damage to the vascular wall, which increases the risk of strokes and heart attacks. It is easier to prevent serious health problems than to treat them.

    Hello, changes in the blood (lymphocytosis) and an increase in lymph nodes indicates the need to undergo an examination to exclude the Epstein-Barr virus. To do this, do an ELISA of blood Ig G and Ig M on EBV. Also hand over ELISA for cytomegalovirus and virus herpes simplex. Contact an infectious disease specialist with the results.
    Regarding the thyroid gland: calcitonin, ionized calcium, parathyroid hormone - these are hormones that are given to clarify the work of the parathyroid glands. The need for examination should be due to the presence of complaints and the corresponding clinical picture. Discuss this question with the internal endocrinologist.
    TSH, T4 and antibodies to TPO should be taken, as this is included in comprehensive examination thyroid gland. Ultrasound should be done once a year to monitor the growth of the nodule in the right lobe.
    Without an additional examination, it is difficult to say whether thyroid disease is the cause of the temperature increase. Sometimes, against the background of hypothyroidism, a decrease in immunity occurs, and as a result, the addition of EBV infection and other problems.

    Hello, there is a complex examination, which is prescribed for subfebrile temperature. It includes abdominal ultrasound, endoscopy, colonoscopy, general blood and urine tests, blood for infection (HIV, RW, hepatitis, viral infections-VEB, CMVI, HSV), X-ray of the lungs, Mantoux test and others.
    Hypothyroidism can lead to subfebrile temperature, but to confirm this, all other organs and systems must be fully examined.
    An increase in the dosage of the drug is justified, since your daughter did not have a significant decrease in TSH levels on 25 micrograms of l-thyroxine. Treat hypothyroidism, even if it is not associated with subfebrile temperature. Keep an eye on your daughter's health. If tachycardia increases, then immediately retake blood for TSH.

    Hello. I'm 22. I'm worried about constant irritability and headaches .. Donated blood for hormones, result: T3 free 6.34. T4 free 20. TSH 1.27. What do you think? T3 seems to be exceeded.

    Hello, a slight increase in T3 is abnormal if TSH is normal. According to the results of the analyzes, you have no data for the pathology of the thyroid gland. For a complete examination it is necessary to do an ultrasound of the thyroid gland. Address to the internal neurologist for the decision of your question.

    I passed the analysis for a period of about 9 weeks, it turned out to be elevated TSH - 4.31. The gynecologist prescribed euthyrox 25 mcg a day immediately and a consultation with an endocrinologist. Due to a tight record, I was at the endocrinologist at 14 weeks and retaken the analysis. Today I took the result - 1.64 mIU / ml. I was instructed to increase the dose to 50 mcg per day. And a second test at 22-26 weeks. I didn't understand why to increase.
    TTG has not fallen enough, time have appointed or nominated increase in a dose? Maybe go to another doctor? I feel good, I do not understand the reasons for the increase.

    Hello, in order to find out the reason for the increase in the dosage of L-thyroxine, it is advisable for you to get to the endocrinologist who prescribed it. Most likely, the doctor was guided by the fact that the period is short and TSH should be even lower. But usually this is typical for the first trimester, and you have already moved into the second. At the moment, you have the right to visit another specialist to get a second opinion.

    Good afternoon I have thyroid-stimulating hormone 13.161 and antibodies to thyroperoxidase - 425. Appointed
    L-thyroxine (dosage 75). They didn't really explain anything. will that be enough. I also take iodine active. I'm waiting for the answer.

    Hello, my daughter is 17 years old. Ultrasound-diffuse changes in the thyroid gland, blood and urine for sugar are normal. Ttg. -0.96. , m4 -11.66, antibodies to thyrocyte peroxidase less than 0.25. Constant irritability (ahead of the exam), hair falls out, rashes on the body. Only a week later to see an endocrinologist, the pediatrician prescribed only iodomarin. What diagnosis can be assumed and what treatment is needed? Thanks for the answer.

    Hello, you have hypothyroidism (a decrease in thyroid hormones) due to autoimmune thyroiditis. This condition occurs due to a malfunction immune system, so it is difficult to eliminate the cause of the disease. Hormone replacement therapy is necessary because TSH is very high. TSH control should be carried out after three months, or earlier if there are changes in the state of health (heartbeat, nervousness, changes in appetite, weight, sleep patterns). You should refuse to take iodine preparations, since the cause of AIT is not a lack of iodine, but an autoimmune process.

    Hello, there are no deviations in the analyzes provided by you, but you can visit a full-time endocrinologist for further examination. These complaints may be symptoms of problems with the central nervous system or with the digestive tract. Pass a full examination at the local therapist (biochemical blood test, abdominal ultrasound, if possible, EGDS, coprogram, etc.)

    Hello, I am 61 years old, according to the results of ultrasound, diffuse-focal changes in the thyroid gland, nodes 7x6 mm, 4x4mm, 13x2mm were found. norm 12-22), ATPO = 2.5 (norm 1-30). The doctor prescribed thyroxine 75 mcg, iodomarin 100 mg, cardiomagnyl 75 mg. But if the tests are normal, why all these drugs? I did not make any complaints to the doctor. I will be very grateful for the answer.

    Good afternoon. I didn't get pregnant for a year. They found problems with the thyroid gland, prescribed l-thyroxine50 (ttg 4.56). From the first cycle, it turns out to get pregnant, retaken TSH - 1.2, the doctor waved his hand and said to leave a dose of 50. The gynecologist prescribed Iodomarin 200. At 7 weeks - a miscarriage. Could the thyroid gland be the cause? Whether to continue to drink a dose of 50?

    Hello, you should re-contact a doctor for a consultation so that he explains the need for hormone replacement therapy. Nodular goiter is not an indication for the appointment of L-thyroxine. Cardiomagnyl should also be used only for certain diseases. You should puncture a nodule that is more than 10 mm long. But this issue should be resolved with uzists, because its width is only 2 mm, that is, it may be too narrow for puncture.

    Hello, the TSH result for the first trimester is very good, so it is unlikely that thyroid problems were the cause of the miscarriage. It is necessary to be well examined for infections, check the blood coagulation system. And it should be remembered that a miscarriage is, first of all, natural selection. Continue to take L-thyroxine at the indicated dose and find a good reproductive gynecologist.

    Good afternoon Please tell me what TSH means - 42.5325, if T4 is free - 7.49 and T3 is free - 2.16. While the thyroid gland was killed by radioactive iodine 6 years ago.
    Please tell me what needs to be done. I made an appointment, but the queue is very long.

    Hello. I am 9 weeks pregnant. Has handed over the analysis TSH - 2,28. Does it need to be lowered? Or is this a normal result for the first trimester?

    Hello, judging by the information provided, you were treated with radioactive iodine in connection with diffuse toxic goiter. This condition is characterized by increased levels of the hormone thyroxine (T4) and decreased TSH (hyperthyroidism). At the moment, the situation is completely opposite - TSH has increased, and free T4 is reduced (hypothyroidism). These are the consequences that have arisen due to radioactive iodine therapy. The meaning of the treatment of hypothyroidism is hormone replacement therapy with L-thyroxine. It is important to choose the right dose of the drug depending on the age and weight of the patient. This should be done by a full-time endocrinologist after a thorough examination and evaluation of the test results provided.

    Hello, in the first trimester, lower TSH numbers are usually observed, but your version of the tode is also a normal variant. You can retest in a month. If TTG grows, then it is necessary to visit or attend the endocrinologist.

    Hello. Two months ago I was diagnosed with primary hypothyroidism. ttg 9.15. the endocrinologist prescribed euthyrox 88 mg (I have been drinking it for almost two months). Today I received a new analysis of TSH 3.74. Haven't been to the doctor yet. please tell me why the symptoms do not go away. they worry me a lot (low pressure 100\70. dizziness. ringing in the ears. weakness. fear. hands are shaking (((

    Good evening, please tell me what does TSH mean - 2.670 μIU / ml, AT-TPO - 16.50 IU / ml, and ultrasound showed the right lobe 35 * 13 * 8 mm, V 1.94 ml, the left lobe 31 * 8 * 9 mm, V 1.11 ml, smooth contours, fine-grained structure

    Good afternoon. I am 36 years old.husband. An ultrasound revealed a multinodular goiter. The dimensions of the formations are from 5 to 13 mm in the right lobe and in the left lobe the formation is 48 mm in diameter. Test results: thyroid-stimulating hormone 1.072 mcU/ml
    Triiodothyronine free 3.21 pg/ml
    Calcium ionized 1.23mmol/l
    That's all the doctor told me to get tested.
    The question is what these indicators indicate and for what purpose the doctor prescribed to use L thyroxine 50, one table each. I Iodomarin 100
    Thank you in advance for your response.

    Hello! I have primary hypothyroidism, the doctor always prescribes me an analysis only for TSH, when I asked why I was not prescribed tests for T3, T4, antibodies to thyroglobulin, antibodies to TP, she answered me that the diagnosis had been made and it was enough to check only TSH. I wanted to know if this is true? Before that, I had another doctor (changed in connection with the move), who diagnosed me, she always prescribed all the tests for me and my readings jumped a lot, they picked up the dosage of the drug for a long time. Thank you in advance!

    Hello, the symptoms of the disease, especially if it started a long time ago, rarely disappear in the first months from the start of treatment. Also, we should not forget that the signs you listed can be associated not only with thyroid disease, but also with problems of other internal organs.
    You do not write your age and weight. Perhaps you can slightly increase the dose of the drug. But it should be remembered that with an overdose, signs of thyrotoxicosis may appear. This will adversely affect the entire body as a whole, especially the nervous and cardiovascular systems.

    Hello, my hormonal levels are within normal limits. According to ultrasound, deviations in the structure of the thyroid gland are quite common. The main thing is that there are no nodal formations.
    You should take iodine preparations in courses of two to three months. Especially if you live in an area that contains little iodine in the environment.

    Hello, it is difficult to comment on the appointment of L-thyroxine, as another doctor recommended it. It is usually used if TSH is above normal. You do not indicate the norm of the laboratory in which you took the blood test. Usually the upper limit is 4.0 mcU/ml. You should discuss with the doctor the reason for the appointment of L-thyroxine, or visit another full-time endocrinologist for a personal examination and resolution of this issue.
    You also need to puncture those nodules that are larger than 10 mm.

    Good afternoon. I am 23 years old. 3 months ago I had a sonography of the thyroid gland, I was diagnosed with diffuse hyperplasia of the thyroid gland within 1 degree. I passed the tests TSH-3.9 (normal 0.5-4.1), T4 free-1.2 (normal 0.85-1.85), antibodies to thyroglobulin 238.6 (normal up to 100). After that, the doctor prescribed l-teroxin 25 mg. I gained about 10 kg in 2 months. Again she passed the tests TSH-2.9 (normal 0.5-4.1), T4 free-1.55 (normal 0.85-1.85). After that, the doctor prescribed to drink l-teroxin 50 mg. After 15 days, she again tested TSH-0.314 (normal 0.27-4.2), and T4 free-1.78 (normal 0.93-1.7). Now the doctor has prescribed to drink 3/4 part of 50 mg l-teriksin. But due to the fact that my free T4 hormone has increased, I am afraid to take the medicine. I haven’t drunk for 10 days, can I start drinking again, or is it not worth it? Not knowing what to do, please help.

    Hello, primary hypothyroidism occurs by different reasons, but is treated in the same way - with the help of hormone replacement therapy with L-thyroxine. And we can control the dosage of this drug only with the help of a blood test for TSH. If you are calmer, you can do a general hormonal profile and those indicators that were previously deviated from the norm. But it will not affect the correction of treatment.

    Hello, you should visit another full-time endocrinologist in order to hear the opinion of a second specialist on your issue. At the moment, I would prescribe you tests on a clean background without L-thyroxine (TSH supersensitive and T4 free). And with fresh results, make an appointment with a doctor.

    Hello. A 4-year-old child, congenital hypothyroidism, we drink L-thyroxine at a dosage of 100, they donated blood for TSH, at a rate of 0.66, she has a result of 0.0143. What to do and how to be? Thank you in advance

    Hello, you need a correction of treatment, but an endocrinologist should deal with this issue after a personal examination of the child.

    Hello. Can a pediatric endocrinologist prescribe L-thyroxine to a child (7 years old) without first taking tests for thyroid hormones?

    Hello, hormone replacement therapy has strict indications, so it is not recommended to prescribe L-thyroxine without examination. You need to do a blood test for TSH, T4 free and antibodies to TPO. Apart from laboratory methods Still it is necessary to pass or take place US of a thyroid gland.

    Good afternoon
    I have hypothyroidism, the endocrinologist prescribed l-thyroxine to start with 25mcg / day. Before I go for a second examination, I need to send tests for TSH, free T4 and antibodies to TPO.
    Tell me, is it necessary to stop taking the drug 1 week before the test? Or does it need to be continued?
    Doctor none special instructions did not give in this respect.

    Good afternoon! child 2 years 10 months. fasting tests were prescribed for antibodies to the TSH receptor 0.4 t4-12.78, t4 total-112.6, t3 total-3.5, t3-free - 6.93, insulin-4.7, c-peptide -1.210, with a load (after eating) insulin-3.6, s -peptide-1.280, m3 free-7.22. Thyroid ultrasound is normal. Increased only t3 free. What could it be? the child quickly gets tired, there is sweating, tearfulness, we do not gain weight and height. started in January 2017 after acetonomia. Do I need to give iodomarin? to the doctor in two weeks.

    Hello, I am 29 years old, height 164, vaga 54.5 kg. I take quetixol (50 mg antipsychotic). consultation with an endocrinologist - the diagnosis is subclinical hypothyroidism, all hormones and antibodies are normal, except for TSH - level 4.2. elevated. ultrasound of the thyroid gland - deshcho changed in size. Conclusion hypoplasia 1 stage. Before taking quetixol in 03 2016, she did tests for thyroid hormones TSH was normal 1.7

    The doctor prescribed yo-sen 1 tablet after meals.

    Hello! Diagnosis: subclinical hypothyroidism, ttg-6.4; St. T4-16.5; St. t-7.3; filed a complaint: sharply gained weight by 12 kg, swelling of the face and legs. 51 years old, 78kg (was weight 66kg) height-156. The doctor quit, there was no treatment ... Can you advise me something in this case? Thank you in advance!

    Good afternoon
    Mom is 80 years old.
    Ultrasound of the thyroid gland - without pathologies.
    TSH = 7.81 μMO / ml at the norm = 0.27 - 4.2 μMO / ml
    ST4 \u003d 0.904 at the rate (indicated in the laboratory sheet) \u003d 0.93 - 1.70
    But! at the rate indicated in the information articles = 0.70 - 1.71
    Separately, I will mention that Creatinine is also increased = 147 at a norm = 44.0-80.0
    Interested in your qualified opinion. Is it subclinical hypothyroidism or already manifest? With such borderline values ​​and at this age, is it necessary to start taking hormones or to abstain? Thanks in advance.

    Good afternoon I am very excited about the question about the hormone TSH and free T4. My TSH is 2.81, and free T4 is 12.1. I take iodamarin 200 once a day. Pregnancy 13.6 weeks. This normal performance And how does it affect the child?

    Hello, TSH is within normal limits, and T4 is free at the lower limit. In such cases, it is imperative to visit a full-time endocrinologist to assess the general state of health and all risk factors. If necessary, the doctor will prescribe hormone replacement therapy.

    Hello, in patients of the older age group, the TSH rate is slightly higher than in other categories of citizens. This is due to the fact that the use of hormone replacement therapy in them can cause complications from the cardiovascular system. Therefore, drugs are prescribed strictly according to indications with a long-term elevated TSH, a clear decrease in free T4 and if there are complaints from the patient (by the way, you do not write why you went to take tests).
    Consult with a full-time endocrinologist regarding management tactics. Usually, control tests are prescribed after three months or earlier if the condition worsens.

    Good afternoon I feel bad, my heart hurts, weakness, I sweat terribly. I am a woman, 60 years old. Problems with the thyroid gland - I'm on L-thyroxine. It is terribly difficult to make an appointment with a doctor, even for a paid endocrinologist. Here are the tests:
    Biochemistry of blood
    Atherogenic coefficient - 5.7
    High density lipoproteins - 0.95 mmol / l
    Low density lipoproteins - 5.05 mmol / l
    Triglycerides - 1.59 mmol / l
    Cholesterol - 6.39 mmol / l
    Hormones and tumor markers
    Thyroid-stimulating hormone - 8.7000 µIU / ml (for the first time so high)
    Tell me, is it necessary to increase the dosage of L-thyroxine and how much?

    Hello, you do not write the level of free T4, and do not voice the dose of l-thyroxine. Therefore, it is difficult to give specific recommendations.
    Increased cholesterol and high density lipoproteins require attention. For further examination, you should do an ultrasound scan of the brachiocephalic arteries. Also, if you have hypertension, close relatives have had strokes or heart attacks, then you should start taking statins at a dose that the doctor will prescribe after a full consultation.

    Hello. I am 25 years old, height 170, weight 48 (it is very difficult to gain weight). On May 16, 2017, after undergoing ultrasound of the thyroid gland, I received the following result: Echogenicity: the parenchyma is isoechoic. Echostructure: heterogeneous due to isoechoic nodes with cystic degeneration in the right lobe 12 mm, 2.6 mm. Conclusion: echo signs of nodular goiter. The result of the puncture is a nodular predominantly colloid goiter with the manifestation of cystic degeneration. Then the doctor did not prescribe an analysis for hormones to me and treatment too. After half a year, I go through the ultrasound again, the result is about the same: in the right lobe isoechogen. node, without active krovosn. 13mm-8mm-12mm, nodular goiter. This time I went to another endocrinologist and I was prescribed a hormone test. I have the following results on December 15, 2017: ttg 3.8 (0.27-4.2 mOd / l), at-tpo 7.58 (up to 34 MOD / ml), t4 free 15.77 (12-22 pmol / l), prolactin 886 ,9 (at a rate of 60-600 in the follicular phase (handed over on the first day of mc). I went to my gynecologist with the problem of elevated prolactin, the doctor prescribed me alactin (half a tablet 0.25 mcg per week for 4 weeks). I drank alactin and re-passed analysis for prolactin (result 158 ​​(normal 109-557), and TSH) since it was close to the upper limit) (result 1.82 (normal 0.4-4.0). I turned to the gynecologist again, and she extended the course of treatment with alactin for another 6 months, advised to take times ttg, since he changed so dramatically and, if necessary, drink L-thyroxine) And the endocrinologist, who initially prescribed an analysis for hormones, said the opposite: “I would not advise you to drink alactin, this is a hormone, why do you need it, drink better Tazalok to maintain prolactin normal and yo-sen for the thyroid gland for 3 months. And I have a dilemma, what to do, who to listen to? Please advise

    Hello, regarding nodular goiter, an annual control is needed. As long as TSH is normal, no treatment is required. In connection with increased level prolactin should continue to take alactin. This is not a hormone, but a drug that lowers the level of the hormone (prolactin). The course of treatment is three months minimum. To exclude problems with the pituitary gland, it is better to do an MRI of the brain. Tazalok is a herbal preparation. Whether it will keep prolactin levels is not known.

    I am 57 years old, weight 86 kg, I drink l-thyroxine 100 for 2 months. In 2017, in November, the thyroid gland was completely removed. I passed on the hormones ltg-0.08, t3-4.6 and t4-19.9, now my health has worsened, nausea, poor sleep, a little tremor, constipation, throws me into a fever. What should I do? maybe a higher dose? waiting for an answer

    Hello, a blood test for TSH shows that it has become less than normal. Usually in such cases, the dose of L-thyroxine is reduced, but for this you should visit an internal endocrinologist. If you have had your thyroid gland removed due to oncology, then endocrinologists always prescribe high doses of L-thyroxine to prevent relapse. Therefore, I do not recommend experimenting on your own.

    analysis of the biopsy showed that there is no oncology, thank God, but I had severe sweating before the operation, so it is now. if the doctor reduces the dosage, is there a chance to get rid of this sweating, is it worse for me both in winter and summer? and is it bad that a blood test for TSH shows less than normal?

    My baby girl is 1 year 11 months old. TSH-2.44 μME / ml (the norm is written 0.61-2.2). T4-norm-0.93. She has Sind.Down. Should I be worried?

    Hello, sweating can be not only due to thyroid disease. But if your TSH is less than normal, then it makes sense to first adjust this indicator (reduce the dose of L-thyroxine). Also ask the endocrinologist for additional examination of sex hormones (especially testosterone). Do an ultrasound gynecological, examined by a neurologist.

    Hello, such situations require control (usually prescribed after three months to do TSH again). Hormones are rarely prescribed right away. You should visit a full-time endocrinologist in order for the doctor to evaluate general state child's health.

    Hello! Prompt, please, and that after the last reception of the endocrinologist I have absolutely got confused. Three years ago I was diagnosed with autoimmune teroiditis, I take L-thyroxine. The doctor who made the diagnosis explained to me that the level of TSH should be from 0.4 to 4. Every 3-4 months I take TSH, it stays at the level of 2-3. A week ago I was at an appointment with another endocrinologist (besides, who made the diagnosis could not get in). The doctor, seeing my analysis of TSH equal to 2 (handed over in March), said that this was a bad analysis, explaining that the analysis of TSH should be approximately 0.1-0.2, thereby increasing the dose of L-thyroxine by 1.5 times . What should I do, tell me?

    Hello, the second endocrinologist is not quite right, since the numbers indicated by him are too small and indicate the presence of hyperthyroidism (too high hormone levels). Such TSH numbers are recommended for patients who have undergone surgery to remove the thyroid gland due to oncology. You should stick to numbers from 0.4 to 4. If you are planning a pregnancy, then the ideal TSH is up to about 2.5. Permalink

    Hello, you definitely need hormone replacement therapy. It is worth starting treatment with 50 or 75 mcg of L-thyroxine. But this should be done under the supervision of an endocrinologist. TSH control after 3 months.

    Good afternoon, I am 39 years old. Male. Height 188 cm. Weight 128 kg.
    Recently, he began to feel unwell, constant headaches, problems with the gastrointestinal tract (flatulence, porridge-shaped stools, aching pain abdominal cavity).
    I turned to the Endocrinologist for a fee before doing an ultrasound of the thyroid (enlarged like a sponge) and donated blood for free T4 hormones - 9.9 and TSH - 10.10. The doctor diagnosed Hypothyroidism, prescribed L-thyroxine 50, 1 tablet in the morning on an empty stomach for 30-40 minutes. before meals. When taking it on the first day, I felt what it means to breathe oxygen, my ankle swelling disappeared, drowsiness disappeared (when you feel that your brains are in porridge, you want to close your eyes and not move), in 1.5 hours I easily passed with ups and downs with launches of 10 km., didn’t pass, but flew, fluttered, while breathing freely through the nose, and not through the mouth, for the first time in my life. The mood improved significantly, became calmer, there are no rheumatic pains in the lower back, knees after walking. I calmly began to do push-ups from the floor , doing the press does not bother me with muscle pain from classes, there are no nightly calf cramps.
    Eight days later, I re-tested free T4 - 15.8 (normal) and TSH - 6.53, the doctor said she was striving for 1.5 - 2.5. Yes, I also began to brew and drink oats, and make a clove of garlic spread with a knife blade and let it lie for 5 minutes, then eat and drink half a glass of whey or kefir. There will be no problems with dysbacteriosis. Garlic for the night, oats three times a day before food. Here is a story. Be healthy, we need to live until retirement 🙂

    Dobryi den. Podskazhite please became dizzy. L Thyroxine I take 50 mg, day 15, can reduce the dosage to 25 mg (half a tablet)? And then a very expensive appointment with a doctor.

    Hello, it is unlikely that the head is spinning from taking L-thyroxine. You do not indicate how long you have been drinking it, what are the last numbers of TSH. Dose adjustment of the drug without a fresh analysis for TSH is not carried out. You should see a neurologist about dizziness and get tested for TSH.

    Thank you. I drink this hormone L-thyroxine for 18 days. From the first day, before taking this drug, the indications were: free T4 - 9.9, and TSH - 10.10, passed on an empty stomach. After 8 days, I did it again, it became free T4 - 15.8, and TSH - 6.53, I also passed it on an empty stomach. This is fine?
    Pressure 130*80 pulse 65

    My son is 27 years old, has been registered with an endocrinologist since the age of 13 with a diagnosis of hypothyroidism. Drinks L-thyroxine dosage -125. 05/28/2018 for a periodic visit to the endocrinologist, in the laboratory of the endocrinological dispensary, I passed an analysis for TSH, the result was -0.153. Transferred to L-thyroxine 100. Today, 05/16/2018, I passed TSH -15.22. Can there be such a difference in such a short time?

    Hello, you should return the previous dose of L-thyroxine, since now TSH is much higher than normal. Your question most likely has the dates mixed up. I so understand, that the difference between analyzes of 12 days. I think that the body reacted in this way to a decrease in the dose of L-thyroxine. For your peace of mind, you can redo the analysis in another laboratory.

    Hello, the result of your tests is still not normal. Since you have been taking L-thyroxine for a short time, you should not change the dosage for now. Although 75 mg can be prescribed for your weight. Give the next analysis in a month. If it is above 4, then the dose should be increased. TSH is used for control. It is not necessary to take T4 free.

    Hello! I had my left thyroid lobe removed in March 2018. After the operation, a month later, TSH was normal, and after three months it showed 5.65. Is this a very high result? And do I need to take pills? Thanks in advance!

Good evening. I am 59 years old, in April 2015 my thyroid gland was completely removed, everything is benign, now I am taking Euthyrox 100. My TSH level is 0.458. Is this normal or do I need to further reduce the dose of the medication?

Thyroid hormones are vital for the body. If there is not enough thyroxine and triiodothyronine, then hypothyroidism develops. This condition is manifested by metabolic disorders and dysfunction of many organ systems. The most dangerous manifestation of hypothyroidism is the appearance and progression of atherosclerosis, anemia, and neuropathy.

One of the most common causes deficiency of thyroid hormones - thyroid surgery. Hypothyroidism is usually caused by thyroidectomy or subtotal resection. These operations remove almost all of the glandular tissue, which means that they sharply reduce the synthesis of thyroid hormones.

IN postoperative period patients are given replacement therapy. Almost all patients are recommended a synthetic analogue of thyroxine (levothyroxine). Pharmacologists produce this hormone in the form of tablets for a single daily dose. Trade names the drug may be different. It depends on the manufacturer. But the composition of the tablets always indicates the main active ingredient - levothyroxine.

Dose selection of levothyroxine

The dose of the drug is selected individually. It is believed that the total requirement in adults is up to 1.75 micrograms per kg of body weight. Pregnant women need even more hormone - up to 2.25 mcg for every kg of weight.

When choosing a dosage, take into account:

  • patient's age;
  • concomitant diseases;
  • the remaining amount of glandular tissue.

More thyroxine is required after the treatment of thyroid cancer, less - after the removal of euthyroid nodular goiter. Carefully dose the drug in patients with heart disease. An excess of thyroxin can worsen the condition of the myocardium and provoke ischemia.

The first dose of the drug is on average from 25 to 150 mcg. Most patients receive 75-100 micrograms of levothyroxine for treatment.

Dose adjustment

The endocrinologist adjusts the hormone dose 6-8 weeks after the start of replacement therapy. Before visiting a specialist, the patient needs to donate blood for thyrotropin (TSH).

When adjusting the dose, the doctor pays attention to the patient's well-being and the level of TSH.

Target values ​​of thyrotropin:

  • in patients after removal of thyroid cancer - 0.1-1 mU / l;
  • in pregnant women - up to 2.5 mU / l in the 1st and 2nd trimesters, up to 3 mU / l in the 3rd trimester;
  • in women planning pregnancy - 0.4-2.5 mU / l;
  • in young and middle-aged patients - 0.4-4 mU / l;
  • in patients with heart disease (primarily coronary artery disease) - up to 10 mU / l;
  • in elderly patients - up to 10 mU / l.

The lower limit of TSH in the elderly and in people with coronary artery disease is set individually. Usually it is enough to achieve a thyrotropin level of 1 mU / l.

All decisions to increase or decrease the dose of the drug are made by the doctor during a personal examination of a patient with hypothyroidism.

Name: Elena, Kharkov.

Question: I am 57 years old. TSH - 6.3. Antibodies to TPO - 205.4. I took L-thyroxine at 50, but what should I do now with such indicators?

Answer:

Your TSH readings are very slightly off the mark.

Thyrotropic hormone is produced by the pituitary gland, its task is to promote the synthesis of thyroxine (T3) and triiodothyronine (T4).

Doctor's explanations about T3, T4, TSH, AT TPO

This process is important for normal metabolism, protein production and energy resources. Therefore, for a complete picture, one would need to know the parameters of these two hormones at the moment.

If the level of T3 and T4 is normal, most likely, we will talk about subclinical hypothyroidism, and with it the symptoms are weak or absent.

As for the analysis of antibodies to TPO, it depends on how the testing was carried out.

If it was an ELISA technique, the normal rate in women over the age of 50 should not exceed 50 IU / ml.

With immunoluminescent analysis, the value can reach up to 100 IU / ml.

Your limit has been exceeded. This effect occurs when the antibodies of the immune system as a result various factors begin to perceive thyroid enzymes as alien and dangerous and try to fight them.

In women during menopause and menopause, a similar phenomenon is not uncommon, and the reason for this is hormonal changes.

- This is a drug whose main active ingredient (levothyroxine) performs the same functions as T3 and T4.

The activity of this element depends on the prescribed dose - in small quantities it provides an anabolic effect.

At higher levels, it stimulates metabolism, stimulates oxidative reactions, accelerates the breakdown of fats, proteins and carbohydrates.

The question is, how long have you been taking the drug, and what were your readings before taking it?

Usually, the doctor adjusts the dosage every two months until the indicators are normal.

The most severe form of hypothyroidism in adults is myxedema, in childhood- cretinism.

The thyroid gland is the most important link in the endocrine system, the result of which is the synthesis of the iodine-containing thyroid hormones thyroxine and triiodothyronine and the hormone calcitonin that regulates calcium metabolism. The normal functioning of the thyroid gland is a necessary condition for the normal functioning of the heart, brain, muscles, reproductive system, support metabolism.

The balance of thyroid hormones is necessary for the body to:

  • uptake of oxygen by cells
  • protein formation (material for new cells),
  • stimulation of the breakdown of fat cells,
  • reproductive stability,
  • development of a healthy nervous system,
  • the formation of mental abilities,
  • improving the release of body heat, etc.

This list does not include all body functions that are affected by thyroid hormones. But he also convincingly shows that with a lack of hormones, their violation occurs.

The balance of thyroid hormones ensures the full development of the body.

How are hormones formed?

main role plays the hormone thyroxine (T4), the formation of which requires a weekly norm of iodine (approximately from the iodine-containing substances entering the body. Substances enter the digestive tract, iodine is absorbed into the blood, from the bloodstream into the thyroid cells, and the latter synthesize the hormone T4 (norm 0 - 22.0 nmol/l free T4).From some part of T4, triiodothyronine (T3) is subsequently formed (norm 2.6 - 5.7 nmol/l free T3).The blood flow carries thyroid hormones throughout the body.

The work of the thyroid gland is controlled by the pituitary hormone - thyroid-stimulating hormone (TSH). Deviation in the production of T4 from the norm leads to an increase or decrease in the hormone TSH, thyroid cells receive a signal about a failure in the system. With a lack of the required concentration of thyroxine and triiodothyronine in the blood, the synthesis of thyroid-stimulating hormone increases sharply, which leads to additional production of thyroid hormones. Analysis of the TSH indicator accurately determines the health status of patients with primary hyperthyroidism. Norm TTG excludes, as a rule, the diagnosis. Diagnosis of the disease and the appointment of treatment begins with a blood test for hormones. Treatment of hypothyroidism is always focused on improving the hormonal background.

The consequences of a lack of thyroid hormones

Deficiency and disturbance of the hormonal balance of a number of T4, T3 and TSH cause:

  1. depressed state of mind
  2. chills,
  3. lethargy, hypersomnia,
  4. mental retardation,
  5. weakening of memory and attention,
  6. dyspnea,
  7. spasms and pain in the muscles,
  8. brittle hair, nails, dry skin,
  9. predisposition to constipation,
  10. propensity for obesity.

Among non-communicable human diseases, iodine deficiency diseases are common. These include an enlarged thyroid gland - endemic goiter (diffuse non-toxic goiter). The presence in the body of thyroid hormones below the norm causes not only the appearance of goiter, but can cause irreversible harm to health.

Iodine deficiency in the developing fetus and children early age could lead to a decline mental development(from oligophrenia to cretinism), speech and hearing disorders, impaired physical development.

Women suffer from anomalies in the action of the reproductive function, accompanied by miscarriages and the birth of dead children.

Adults experience disturbances in the thought process, a sharp loss of cognitive function, and other abnormalities. The most negative traces of iodine deficiency affect the early stages of the formation of a child, starting from intrauterine development.

On the planet, more than a quarter of people from the entire population of the Earth have an unnaturally low level of iodine intake, this increases the likelihood of thyroid diseases.

The main source of iodine for the body is food, only a tenth of the need comes from water and air. The daily requirement for "babies" is 50 mcg, for children under six years old - 90 mcg, up to twelve years -120 mcg, for adolescents and adults - 150 mcg, for pregnant and lactating women - about 200 mcg. It is useful to introduce foods enriched with iodine into the diet. Red caviar, persimmon, buckwheat, cod liver, sea kale is an incomplete list of such products.

For all his life, a person consumes about one teaspoon of iodine.

How does the body react to iodine deficiency?

A whole reform is being carried out in the work of the thyroid gland. A decrease in the synthesis of thyroxine and triiodothyronine is followed by a sharp activation of the secretion of thyroid-stimulating hormone. Elevated levels of the hormone TSH contribute to adaptation to iodine deficiency. The iodine replenishment of the thyroid gland is activated, the processing of thyroid hormones is accelerated, the thyroid gland grows, and goiter appears. This is how the body's compensatory abilities are manifested, focused on stabilizing the homeostasis of thyroid hormones in the thyroid gland.

When the body's compensatory resources run out in a constant mode of iodine deficiency, the stage of development of hypothyroidism sets in, causing a disorder in mental and physical development. Hyperthyroidism manifests itself with the formation of thyrotoxic adenoma, diffuse toxic goiter, some forms of autoimmune thyroiditis. modern medicine all iodine deficiency diseases, considered as a manifestation of hypothyroidism, are included in the list of the most important problems. Health care in all countries is focused on the treatment and prevention of diseases.

Treatment

Currently, replacement therapy with levothyroxine, a synthetic analogue of thyroid hormones, is used to treat hypothyroidism. The use of drugs that act as hormones should be with an absolute or relative insufficiency of the “thyroid gland” function. They stimulate the vital activity of those cells that are affected by hormones synthesized in the body. These analogs act on cells with which hormones synthesized in the thyroid gland interact.

One of these drugs, L-thyroxine (levothyroxine sodium), which is based on a synthetic analogue of the thyroid hormone, is widely used for replacement and suppressive therapy. If hypothyroidism is diagnosed, how to drink L-thyroxine?

What you need to know about the drug?

  1. Official name and manufacturer: L-Thyroxine 50 Berlin-Chemie and L-Thyroxine 100 Berlin-Chemie.
  2. Name active substance: levothyroxine sodium.
  3. Composition: 1 tablet L-Thyroxin 50 Berlin-Chemie contains sodium levothyroxine 50 mcg; 25 pieces in a blister, 2 blisters in a box. 1 tablet L-Thyroxine 100 Berlin-Chemie - 100 mcg; in a blister 25 pieces, in a box of 2 or 4 blisters.
  4. It is prescribed to eliminate the lack of thyroid hormones.
  5. The result comes in treatment in three to five days. Take on an empty stomach, absorption occurs in small intestine by 80%. The drug has an optimal plasma concentration on average six hours after administration. Almost completely combines with plasma proteins (99%). Decomposes in the liver, muscles, brain.
  6. It is prescribed for all types of hypothyroidism; recommended for eutheriod goiter. It is permissible to use women when carrying and breastfeeding a baby.
  7. The drug is dangerous to use in hyperthyroidism, angina pectoris, myocarditis, acute myocardial infarction, elderly patients with goiter, adrenal disease.
  8. It is not recommended to take with ischemia of the heart, tachycardia, heart failure, with a severe form of hypothyroidism.
  9. Rules for admission and dosage. In the morning, before eating, take the tablet with a small amount of water. The initial dose per day for adults is in the range of 25-100 mcg, to maintain a constant level - 125-250 mcg; children are given at the beginning daily dose- 12, 5-50 mcg, supporting is calculated per 1 m 2 of body surface - 100-150 mcg.
  10. Possible complications. Very rarely, a transient increase in body weight is observed, with large doses in children - a disorder of kidney function.
  11. Overdose. There are signs of thyrotoxicosis. Counteracts the use of beta-blockers.
  12. Consistency with other drugs. It blunts the action of insulin and antidiabetic agents, increases the effect of indirect anticoagulants. Furosemide, salicylates, phenytoin increase the concentration in the blood. Cholestyramine reduces absorption.
  13. Storage method. In a dark place.

Bibliography

  1. Restoration of the thyroid gland - Ushakov A.V. – Patient Guide
  2. Diseases of the thyroid gland - Valdina E.A. – Practical guide
  3. Diseases of the thyroid gland. - Moscow: Mashinostroenie, 2007. - 432 p.
  4. Diseases of the thyroid gland. error-free treatment. - M.: AST, Owl, VKT, 2007. - 128 p.
  5. Henry, M. Cronenberg Diseases of the thyroid gland / Henry M. Cronenberg et al. - M .: Reed Elsiver, 2010. - 392 p.
  6. Grekova, T. Everything you didn't know about the thyroid gland / T. Grekova, N. Meshcheryakova. – M.: Tsentrpoligraf, 2014. – 254 p.
  7. Danilova, N.A. Diseases of the thyroid gland. Effective Methods treatment and prevention / N.A. Danilova. – M.: Vector, 2012. – 160 p.

⚕️ Olga Alexandrovna Melikhova - endocrinologist, 2 years of experience.

Deals with issues of prevention, diagnosis and treatment of diseases of the endocrine system: thyroid gland, pancreas, adrenal glands, pituitary gland, gonads, parathyroid glands, thymus etc.



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